162 related articles for article (PubMed ID: 15320728)
1. The application of x-ray, NMR, and molecular modeling in the design of MMP inhibitors.
Rush TS; Powers R
Curr Top Med Chem; 2004; 4(12):1311-27. PubMed ID: 15320728
[TBL] [Abstract][Full Text] [Related]
2. The design and synthesis of aryl hydroxamic acid inhibitors of MMPs and TACE.
Levin JI
Curr Top Med Chem; 2004; 4(12):1289-310. PubMed ID: 15320727
[TBL] [Abstract][Full Text] [Related]
3. Design strategies for the identification of MMP-13 and Tace inhibitors.
Skotnicki JS; DiGrandi MJ; Levin JI
Curr Opin Drug Discov Devel; 2003 Sep; 6(5):742-59. PubMed ID: 14579524
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis and evaluation of novel azasugar-based MMP/ADAM inhibitors.
Moriyama H; Tsukida T; Inoue Y; Kondo H; Yoshino K; Nishimura S
Bioorg Med Chem Lett; 2003 Aug; 13(16):2741-4. PubMed ID: 12873505
[TBL] [Abstract][Full Text] [Related]
5. Structure--activity relationships of azasugar-based MMP/ADAM inhibitors.
Moriyama H; Tsukida T; Inoue Y; Kondo H; Yoshino K; Nishimura S
Bioorg Med Chem Lett; 2003 Aug; 13(16):2737-40. PubMed ID: 12873504
[TBL] [Abstract][Full Text] [Related]
6. A comparison of the binding sites of matrix metalloproteinases and tumor necrosis factor-alpha converting enzyme: implications for selectivity.
Lukacova V; Zhang Y; Kroll DM; Raha S; Comez D; Balaz S
J Med Chem; 2005 Apr; 48(7):2361-70. PubMed ID: 15801829
[TBL] [Abstract][Full Text] [Related]
7. Chromen-based TNF-alpha converting enzyme (TACE) inhibitors: design, synthesis, and biological evaluation.
Chun K; Park SK; Kim HM; Choi Y; Kim MH; Park CH; Joe BY; Chun TG; Choi HM; Lee HY; Hong SH; Kim MS; Nam KY; Han G
Bioorg Med Chem; 2008 Jan; 16(1):530-5. PubMed ID: 17936631
[TBL] [Abstract][Full Text] [Related]
8. Beta-aryl-succinic acid hydroxamates as dual inhibitors of matrix metalloproteinases and tumor necrosis factor alpha converting enzyme.
Kottirsch G; Koch G; Feifel R; Neumann U
J Med Chem; 2002 May; 45(11):2289-93. PubMed ID: 12014967
[TBL] [Abstract][Full Text] [Related]
9. Benzodiazepine inhibitors of the MMPs and TACE.
Nelson FC; Delos Santos E; Levin JI; Chen JM; Skotnicki JS; DiJoseph JF; Sharr MA; Sung A; Killar LM; Cowling R; Jin G; Roth CE; Albright JD
Bioorg Med Chem Lett; 2002 Oct; 12(20):2867-70. PubMed ID: 12270165
[TBL] [Abstract][Full Text] [Related]
10. Non-hydroxamate 5-phenylpyrimidine-2,4,6-trione derivatives as selective inhibitors of tumor necrosis factor-alpha converting enzyme.
Duan JJ; Lu Z; Wasserman ZR; Liu RQ; Covington MB; Decicco CP
Bioorg Med Chem Lett; 2005 Jun; 15(12):2970-3. PubMed ID: 15908214
[TBL] [Abstract][Full Text] [Related]
11. Discovery of selective phosphonamide-based inhibitors of tumor necrosis factor-alpha converting enzyme (TACE).
Sawa M; Kurokawa K; Inoue Y; Kondo H; Yoshino K
Bioorg Med Chem Lett; 2003 Jun; 13(12):2021-4. PubMed ID: 12781187
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and structure-activity relationship of N-substituted 4-arylsulfonylpiperidine-4-hydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritis.
Aranapakam V; Davis JM; Grosu GT; Baker J; Ellingboe J; Zask A; Levin JI; Sandanayaka VP; Du M; Skotnicki JS; DiJoseph JF; Sung A; Sharr MA; Killar LM; Walter T; Jin G; Cowling R; Tillett J; Zhao W; McDevitt J; Xu ZB
J Med Chem; 2003 Jun; 46(12):2376-96. PubMed ID: 12773042
[TBL] [Abstract][Full Text] [Related]
13. Novel thiol-based TACE inhibitors. Part 2: Rational design, synthesis, and SAR of thiol-containing aryl sulfones.
Bandarage UK; Wang T; Come JH; Perola E; Wei Y; Rao BG
Bioorg Med Chem Lett; 2008 Jan; 18(1):44-8. PubMed ID: 18054488
[TBL] [Abstract][Full Text] [Related]
14. Sulfonate ester hydroxamic acids as potent and selective inhibitors of TACE enzyme.
Levin JI; Du MT
Drug Des Discov; 2003; 18(4):123-6. PubMed ID: 15553924
[TBL] [Abstract][Full Text] [Related]
15. Identification of a selectivity determinant for inhibition of tumor necrosis factor-alpha converting enzyme by comparative modeling.
Wasserman ZR; Duan JJ; Voss ME; Xue CB; Cherney RJ; Nelson DJ; Hardman KD; Decicco CP
Chem Biol; 2003 Mar; 10(3):215-23. PubMed ID: 12670535
[TBL] [Abstract][Full Text] [Related]
16. Discovery of gamma-lactam hydroxamic acids as selective inhibitors of tumor necrosis factor alpha converting enzyme: design, synthesis, and structure-activity relationships.
Duan JJ; Chen L; Wasserman ZR; Lu Z; Liu RQ; Covington MB; Qian M; Hardman KD; Magolda RL; Newton RC; Christ DD; Wexler RR; Decicco CP
J Med Chem; 2002 Nov; 45(23):4954-7. PubMed ID: 12408705
[TBL] [Abstract][Full Text] [Related]
17. Pronounced diversity in electronic and chemical properties between the catalytic zinc sites of tumor necrosis factor-alpha-converting enzyme and matrix metalloproteinases despite their high structural similarity.
Solomon A; Rosenblum G; Gonzales PE; Leonard JD; Mobashery S; Milla ME; Sagi I
J Biol Chem; 2004 Jul; 279(30):31646-54. PubMed ID: 15102849
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and structure-activity relationship of alpha-sulfonylhydroxamic acids as novel, orally active matrix metalloproteinase inhibitors for the treatment of osteoarthritis.
Aranapakam V; Grosu GT; Davis JM; Hu B; Ellingboe J; Baker JL; Skotnicki JS; Zask A; DiJoseph JF; Sung A; Sharr MA; Killar LM; Walter T; Jin G; Cowling R
J Med Chem; 2003 Jun; 46(12):2361-75. PubMed ID: 12773041
[TBL] [Abstract][Full Text] [Related]
19. N-O-isopropyl sulfonamido-based hydroxamates: design, synthesis and biological evaluation of selective matrix metalloproteinase-13 inhibitors as potential therapeutic agents for osteoarthritis.
Nuti E; Casalini F; Avramova SI; Santamaria S; Cercignani G; Marinelli L; La Pietra V; Novellino E; Orlandini E; Nencetti S; Tuccinardi T; Martinelli A; Lim NH; Visse R; Nagase H; Rossello A
J Med Chem; 2009 Aug; 52(15):4757-73. PubMed ID: 19606871
[TBL] [Abstract][Full Text] [Related]
20. Matrix metalloproteinase target family landscape: a chemometrical approach to ligand selectivity based on protein binding site analysis.
Pirard B; Matter H
J Med Chem; 2006 Jan; 49(1):51-69. PubMed ID: 16392792
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]