These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

869 related articles for article (PubMed ID: 15322239)

  • 1. DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.
    Caporali S; Falcinelli S; Starace G; Russo MT; Bonmassar E; Jiricny J; D'Atri S
    Mol Pharmacol; 2004 Sep; 66(3):478-91. PubMed ID: 15322239
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Abrogation of the Chk1-mediated G(2) checkpoint pathway potentiates temozolomide-induced toxicity in a p53-independent manner in human glioblastoma cells.
    Hirose Y; Berger MS; Pieper RO
    Cancer Res; 2001 Aug; 61(15):5843-9. PubMed ID: 11479224
    [TBL] [Abstract][Full Text] [Related]  

  • 3. CHK1 and CHK2 are differentially involved in mismatch repair-mediated 6-thioguanine-induced cell cycle checkpoint responses.
    Yan T; Desai AB; Jacobberger JW; Sramkoski RM; Loh T; Kinsella TJ
    Mol Cancer Ther; 2004 Sep; 3(9):1147-57. PubMed ID: 15367709
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase.
    Stojic L; Mojas N; Cejka P; Di Pietro M; Ferrari S; Marra G; Jiricny J
    Genes Dev; 2004 Jun; 18(11):1331-44. PubMed ID: 15175264
    [TBL] [Abstract][Full Text] [Related]  

  • 5. AKT is activated in an ataxia-telangiectasia and Rad3-related-dependent manner in response to temozolomide and confers protection against drug-induced cell growth inhibition.
    Caporali S; Levati L; Starace G; Ragone G; Bonmassar E; Alvino E; D'Atri S
    Mol Pharmacol; 2008 Jul; 74(1):173-83. PubMed ID: 18413665
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human monocytes undergo excessive apoptosis following temozolomide activating the ATM/ATR pathway while dendritic cells and macrophages are resistant.
    Bauer M; Goldstein M; Heylmann D; Kaina B
    PLoS One; 2012; 7(6):e39956. PubMed ID: 22768182
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ATM-dependent CHK2 activation induced by anticancer agent, irofulven.
    Wang J; Wiltshire T; Wang Y; Mikell C; Burks J; Cunningham C; Van Laar ES; Waters SJ; Reed E; Wang W
    J Biol Chem; 2004 Sep; 279(38):39584-92. PubMed ID: 15269203
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Cadmium-induced DNA damage triggers G(2)/M arrest via chk1/2 and cdc2 in p53-deficient kidney proximal tubule cells.
    Bork U; Lee WK; Kuchler A; Dittmar T; Thévenod F
    Am J Physiol Renal Physiol; 2010 Feb; 298(2):F255-65. PubMed ID: 19923412
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage.
    Helt CE; Cliby WA; Keng PC; Bambara RA; O'Reilly MA
    J Biol Chem; 2005 Jan; 280(2):1186-92. PubMed ID: 15533933
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cytotoxic effects of temozolomide and radiation are additive- and schedule-dependent.
    Chalmers AJ; Ruff EM; Martindale C; Lovegrove N; Short SC
    Int J Radiat Oncol Biol Phys; 2009 Dec; 75(5):1511-9. PubMed ID: 19931733
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mismatch repair-mediated G2/M arrest by 6-thioguanine involves the ATR-Chk1 pathway.
    Yamane K; Taylor K; Kinsella TJ
    Biochem Biophys Res Commun; 2004 May; 318(1):297-302. PubMed ID: 15110787
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
    Tyagi A; Singh RP; Agarwal C; Siriwardana S; Sclafani RA; Agarwal R
    Carcinogenesis; 2005 Nov; 26(11):1978-87. PubMed ID: 15975956
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
    Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
    Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
    [TBL] [Abstract][Full Text] [Related]  

  • 14. ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis.
    Pabla N; Huang S; Mi QS; Daniel R; Dong Z
    J Biol Chem; 2008 Mar; 283(10):6572-83. PubMed ID: 18162465
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites.
    Das KC; Dashnamoorthy R
    Am J Physiol Lung Cell Mol Physiol; 2004 Jan; 286(1):L87-97. PubMed ID: 12959929
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ATM inhibitor KU-55933 increases the TMZ responsiveness of only inherently TMZ sensitive GBM cells.
    Nadkarni A; Shrivastav M; Mladek AC; Schwingler PM; Grogan PT; Chen J; Sarkaria JN
    J Neurooncol; 2012 Dec; 110(3):349-57. PubMed ID: 23054561
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Early Chk1 phosphorylation is driven by temozolomide-induced, DNA double strand break- and mismatch repair-independent DNA damage.
    Ito M; Ohba S; Gaensler K; Ronen SM; Mukherjee J; Pieper RO
    PLoS One; 2013; 8(5):e62351. PubMed ID: 23667469
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2.
    Adamson AW; Beardsley DI; Kim WJ; Gao Y; Baskaran R; Brown KD
    Mol Biol Cell; 2005 Mar; 16(3):1513-26. PubMed ID: 15647386
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Genistein induces G2/M cell cycle arrest and apoptosis of human ovarian cancer cells via activation of DNA damage checkpoint pathways.
    Ouyang G; Yao L; Ruan K; Song G; Mao Y; Bao S
    Cell Biol Int; 2009 Dec; 33(12):1237-44. PubMed ID: 19732843
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.
    Gatei M; Sloper K; Sorensen C; Syljuäsen R; Falck J; Hobson K; Savage K; Lukas J; Zhou BB; Bartek J; Khanna KK
    J Biol Chem; 2003 Apr; 278(17):14806-11. PubMed ID: 12588868
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 44.