BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

366 related articles for article (PubMed ID: 15326314)

  • 1. The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
    Bergt C; Pennathur S; Fu X; Byun J; O'Brien K; McDonald TO; Singh P; Anantharamaiah GM; Chait A; Brunzell J; Geary RL; Oram JF; Heinecke JW
    Proc Natl Acad Sci U S A; 2004 Aug; 101(35):13032-7. PubMed ID: 15326314
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tyrosine 192 in apolipoprotein A-I is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport.
    Shao B; Bergt C; Fu X; Green P; Voss JC; Oda MN; Oram JF; Heinecke JW
    J Biol Chem; 2005 Feb; 280(7):5983-93. PubMed ID: 15574409
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein A-I.
    Shao B; Oda MN; Bergt C; Fu X; Green PS; Brot N; Oram JF; Heinecke JW
    J Biol Chem; 2006 Apr; 281(14):9001-4. PubMed ID: 16497665
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Site-specific oxidation of apolipoprotein A-I impairs cholesterol export by ABCA1, a key cardioprotective function of HDL.
    Shao B
    Biochim Biophys Acta; 2012 Mar; 1821(3):490-501. PubMed ID: 22178192
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
    Hazen SL; Heinecke JW
    J Clin Invest; 1997 May; 99(9):2075-81. PubMed ID: 9151778
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species.
    Pennathur S; Bergt C; Shao B; Byun J; Kassim SY; Singh P; Green PS; McDonald TO; Brunzell J; Chait A; Oram JF; O'brien K; Geary RL; Heinecke JW
    J Biol Chem; 2004 Oct; 279(41):42977-83. PubMed ID: 15292228
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Pathways for oxidation of high-density lipoprotein in human cardiovascular disease.
    Shao B; Oda MN; Vaisar T; Oram JF; Heinecke JW
    Curr Opin Mol Ther; 2006 Jun; 8(3):198-205. PubMed ID: 16774039
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oxidation of apolipoprotein A-I by myeloperoxidase impairs the initial interactions with ABCA1 required for signaling and cholesterol export.
    Shao B; Tang C; Heinecke JW; Oram JF
    J Lipid Res; 2010 Jul; 51(7):1849-58. PubMed ID: 20064972
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Impact of HDL oxidation by the myeloperoxidase system on sterol efflux by the ABCA1 pathway.
    Shao B; Heinecke JW
    J Proteomics; 2011 Oct; 74(11):2289-99. PubMed ID: 21501700
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Humans with atherosclerosis have impaired ABCA1 cholesterol efflux and enhanced high-density lipoprotein oxidation by myeloperoxidase.
    Shao B; Tang C; Sinha A; Mayer PS; Davenport GD; Brot N; Oda MN; Zhao XQ; Heinecke JW
    Circ Res; 2014 May; 114(11):1733-42. PubMed ID: 24647144
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acrolein impairs ATP binding cassette transporter A1-dependent cholesterol export from cells through site-specific modification of apolipoprotein A-I.
    Shao B; Fu X; McDonald TO; Green PS; Uchida K; O'Brien KD; Oram JF; Heinecke JW
    J Biol Chem; 2005 Oct; 280(43):36386-96. PubMed ID: 16126721
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lysine residues direct the chlorination of tyrosines in YXXK motifs of apolipoprotein A-I when hypochlorous acid oxidizes high density lipoprotein.
    Bergt C; Fu X; Huq NP; Kao J; Heinecke JW
    J Biol Chem; 2004 Feb; 279(9):7856-66. PubMed ID: 14660678
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease.
    Zheng L; Nukuna B; Brennan ML; Sun M; Goormastic M; Settle M; Schmitt D; Fu X; Thomson L; Fox PL; Ischiropoulos H; Smith JD; Kinter M; Hazen SL
    J Clin Invest; 2004 Aug; 114(4):529-41. PubMed ID: 15314690
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions.
    Shao B; Pennathur S; Heinecke JW
    J Biol Chem; 2012 Feb; 287(9):6375-86. PubMed ID: 22219194
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein.
    Shao B; Oda MN; Oram JF; Heinecke JW
    Chem Res Toxicol; 2010 Mar; 23(3):447-54. PubMed ID: 20043647
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Myeloperoxidase: an inflammatory enzyme for generating dysfunctional high density lipoprotein.
    Shao B; Oda MN; Oram JF; Heinecke JW
    Curr Opin Cardiol; 2006 Jul; 21(4):322-8. PubMed ID: 16755201
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Localization of nitration and chlorination sites on apolipoprotein A-I catalyzed by myeloperoxidase in human atheroma and associated oxidative impairment in ABCA1-dependent cholesterol efflux from macrophages.
    Zheng L; Settle M; Brubaker G; Schmitt D; Hazen SL; Smith JD; Kinter M
    J Biol Chem; 2005 Jan; 280(1):38-47. PubMed ID: 15498770
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Myeloperoxidase-derived oxidants modify apolipoprotein A-I and generate dysfunctional high-density lipoproteins: comparison of hypothiocyanous acid (HOSCN) with hypochlorous acid (HOCl).
    Hadfield KA; Pattison DI; Brown BE; Hou L; Rye KA; Davies MJ; Hawkins CL
    Biochem J; 2013 Jan; 449(2):531-42. PubMed ID: 23088652
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Immunohistochemical evidence for the myeloperoxidase/H2O2/halide system in human atherosclerotic lesions: colocalization of myeloperoxidase and hypochlorite-modified proteins.
    Malle E; Waeg G; Schreiber R; Gröne EF; Sattler W; Gröne HJ
    Eur J Biochem; 2000 Jul; 267(14):4495-503. PubMed ID: 10880973
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lipid-bound apolipoproteins in tyrosyl radical-oxidized HDL stabilize ABCA1 like lipid-free apolipoprotein A-I.
    Hossain MA; Ngeth S; Chan T; Oda MN; Francis GA
    BMC Biochem; 2012 Jan; 13():1. PubMed ID: 22248050
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.