134 related articles for article (PubMed ID: 15327314)
1. Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine a: design, synthesis, and activity studies leading to a potent simplified derivative.
Romo D; Choi NS; Li S; Buchler I; Shi Z; Liu JO
J Am Chem Soc; 2004 Sep; 126(34):10582-8. PubMed ID: 15327314
[TBL] [Abstract][Full Text] [Related]
2. Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product Pateamine A.
Low WK; Dang Y; Schneider-Poetsch T; Shi Z; Choi NS; Rzasa RM; Shea HA; Li S; Park K; Ma G; Romo D; Liu JO
Methods Enzymol; 2007; 431():303-24. PubMed ID: 17923240
[TBL] [Abstract][Full Text] [Related]
3. Investigation of the mechanism of action of a potent pateamine A analog, des-methyl, des-amino pateamine A (DMDAPatA).
Kommaraju SS; Aulicino J; Gobbooru S; Li J; Zhu M; Romo D; Low WK
Biochem Cell Biol; 2020 Aug; 98(4):502-510. PubMed ID: 32008367
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of eukaryotic translation initiation by the marine natural product pateamine A.
Low WK; Dang Y; Schneider-Poetsch T; Shi Z; Choi NS; Merrick WC; Romo D; Liu JO
Mol Cell; 2005 Dec; 20(5):709-22. PubMed ID: 16337595
[TBL] [Abstract][Full Text] [Related]
5. Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A.
Kuznetsov G; Xu Q; Rudolph-Owen L; Tendyke K; Liu J; Towle M; Zhao N; Marsh J; Agoulnik S; Twine N; Parent L; Chen Z; Shie JL; Jiang Y; Zhang H; Du H; Boivin R; Wang Y; Romo D; Littlefield BA
Mol Cancer Ther; 2009 May; 8(5):1250-60. PubMed ID: 19417157
[TBL] [Abstract][Full Text] [Related]
6. Stopping trouble before it starts.
Clardy J
ACS Chem Biol; 2006 Feb; 1(1):17-9. PubMed ID: 17163634
[TBL] [Abstract][Full Text] [Related]
7. Substrate-dependent targeting of eukaryotic translation initiation factor 4A by pateamine A: negation of domain-linker regulation of activity.
Low WK; Dang Y; Bhat S; Romo D; Liu JO
Chem Biol; 2007 Jun; 14(6):715-27. PubMed ID: 17584618
[TBL] [Abstract][Full Text] [Related]
8. Synthesis of a simplified triazole analogue of pateamine A.
Hemi Cumming A; Brown SL; Tao X; Cuyamendous C; Field JJ; Miller JH; Harvey JE; Teesdale-Spittle PH
Org Biomol Chem; 2016 Jun; 14(22):5117-27. PubMed ID: 27180995
[TBL] [Abstract][Full Text] [Related]
9. Creating novel translation inhibitors to target pro-survival proteins in chronic lymphocytic leukemia.
Chen R; Zhu M; Chaudhari RR; Robles O; Chen Y; Skillern W; Qin Q; Wierda WG; Zhang S; Hull KG; Romo D; Plunkett W
Leukemia; 2019 Jul; 33(7):1663-1674. PubMed ID: 30700841
[TBL] [Abstract][Full Text] [Related]
10. Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A.
Naineni SK; Liang J; Hull K; Cencic R; Zhu M; Northcote P; Teesdale-Spittle P; Romo D; Nagar B; Pelletier J
Cell Chem Biol; 2021 Jun; 28(6):825-834.e6. PubMed ID: 33412110
[TBL] [Abstract][Full Text] [Related]
11. Novel inhibitors of human histone deacetylases: design, synthesis, enzyme inhibition, and cancer cell growth inhibition of SAHA-based non-hydroxamates.
Suzuki T; Nagano Y; Kouketsu A; Matsuura A; Maruyama S; Kurotaki M; Nakagawa H; Miyata N
J Med Chem; 2005 Feb; 48(4):1019-32. PubMed ID: 15715470
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis, and biological evaluation of artificial macrosphelides in the search for new apoptosis-inducing agents.
Matsuya Y; Kobayashi Y; Kawaguchi T; Hori A; Watanabe Y; Ishihara K; Ahmed K; Wei ZL; Yu DY; Zhao QL; Kondo T; Nemoto H
Chemistry; 2009 Jun; 15(23):5799-813. PubMed ID: 19370747
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of simplified tedanolide analogues--connecting tedanolide to myriaporone and gephyronic acid.
Diaz N; Naini A; Muthukumar Y; Sasse F; Kalesse M
ChemMedChem; 2012 May; 7(5):771-5. PubMed ID: 22383258
[TBL] [Abstract][Full Text] [Related]
14. Catalysis-Based Total Syntheses of Pateamine A and DMDA-Pat A.
Zhuo CX; Fürstner A
J Am Chem Soc; 2018 Aug; 140(33):10514-10523. PubMed ID: 30056701
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and biological evaluation of benzothiazole derivatives as potent antitumor agents.
Yoshida M; Hayakawa I; Hayashi N; Agatsuma T; Oda Y; Tanzawa F; Iwasaki S; Koyama K; Furukawa H; Kurakata S; Sugano Y
Bioorg Med Chem Lett; 2005 Jul; 15(14):3328-32. PubMed ID: 15955697
[TBL] [Abstract][Full Text] [Related]
16. Discovery and potency optimization of 2-amino-5-arylmethyl-1,3-thiazole derivatives as potential therapeutic agents for prostate cancer.
Krasavin M; Karapetian R; Konstantinov I; Gezentsvey Y; Bukhryakov K; Godovykh E; Soldatkina O; Lavrovsky Y; Sosnov AV; Gakh AA
Arch Pharm (Weinheim); 2009 Jul; 342(7):420-7. PubMed ID: 19544302
[TBL] [Abstract][Full Text] [Related]
17. In-depth study of tripeptide-based alpha-ketoheterocycles as inhibitors of thrombin. Effective utilization of the S1' subsite and its implications to structure-based drug design.
Costanzo MJ; Almond HR; Hecker LR; Schott MR; Yabut SC; Zhang HC; Andrade-Gordon P; Corcoran TW; Giardino EC; Kauffman JA; Lewis JM; de Garavilla L; Haertlein BJ; Maryanoff BE
J Med Chem; 2005 Mar; 48(6):1984-2008. PubMed ID: 15771442
[TBL] [Abstract][Full Text] [Related]
18. Total synthesis of rapamycin.
Ley SV; Tackett MN; Maddess ML; Anderson JC; Brennan PE; Cappi MW; Heer JP; Helgen C; Kori M; Kouklovsky C; Marsden SP; Norman J; Osborn DP; Palomero MA; Pavey JB; Pinel C; Robinson LA; Schnaubelt J; Scott JS; Spilling CD; Watanabe H; Wesson KE; Willis MC
Chemistry; 2009; 15(12):2874-914. PubMed ID: 19204960
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological evaluation of α,β-unsaturated lactones as potent immunosuppressive agents.
Lee SM; Lee WG; Kim YC; Ko H
Bioorg Med Chem Lett; 2011 Oct; 21(19):5726-9. PubMed ID: 21873054
[TBL] [Abstract][Full Text] [Related]
20. RNA-mediated sequestration of the RNA helicase eIF4A by Pateamine A inhibits translation initiation.
Bordeleau ME; Cencic R; Lindqvist L; Oberer M; Northcote P; Wagner G; Pelletier J
Chem Biol; 2006 Dec; 13(12):1287-95. PubMed ID: 17185224
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
