BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

160 related articles for article (PubMed ID: 15331050)

  • 1. Design of a gene family screening library targeting G-protein coupled receptors.
    Lamb ML; Bradley EK; Beaton G; Bondy SS; Castellino AJ; Gibbons PA; Suto MJ; Grootenhuis PD
    J Mol Graph Model; 2004 Sep; 23(1):15-21. PubMed ID: 15331050
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The 7 TM G-protein-coupled receptor target family.
    Jacoby E; Bouhelal R; Gerspacher M; Seuwen K
    ChemMedChem; 2006 Aug; 1(8):761-82. PubMed ID: 16902930
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Strategies for designing GPCR-focused libraries and screening sets.
    Jimonet P; Jäger R
    Curr Opin Drug Discov Devel; 2004 May; 7(3):325-33. PubMed ID: 15216936
    [TBL] [Abstract][Full Text] [Related]  

  • 4. G-protein-coupled receptor affinity prediction based on the use of a profiling dataset: QSAR design, synthesis, and experimental validation.
    Rolland C; Gozalbes R; Nicolaï E; Paugam MF; Coussy L; Barbosa F; Horvath D; Revah F
    J Med Chem; 2005 Oct; 48(21):6563-74. PubMed ID: 16220973
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ligand identification for G-protein-coupled receptors: a lead generation perspective.
    Bleicher KH; Green LG; Martin RE; Rogers-Evans M
    Curr Opin Chem Biol; 2004 Jun; 8(3):287-96. PubMed ID: 15183327
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Are target-family-privileged substructures truly privileged?
    Schnur DM; Hermsmeier MA; Tebben AJ
    J Med Chem; 2006 Mar; 49(6):2000-9. PubMed ID: 16539387
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The synergy between combinatorial chemistry and high-throughput screening.
    Diller DJ
    Curr Opin Drug Discov Devel; 2008 May; 11(3):346-55. PubMed ID: 18428088
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development and virtual screening of target libraries.
    Rognan D
    J Physiol Paris; 2006; 99(2-3):232-44. PubMed ID: 16459061
    [TBL] [Abstract][Full Text] [Related]  

  • 9. G-protein-coupled receptor-focused drug discovery using a target class platform approach.
    Heilker R; Wolff M; Tautermann CS; Bieler M
    Drug Discov Today; 2009 Mar; 14(5-6):231-40. PubMed ID: 19121411
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A screening library for peptide activated G-protein coupled receptors. 1. The test set.
    Lavrador K; Murphy B; Saunders J; Struthers S; Wang X; Williams J
    J Med Chem; 2004 Dec; 47(27):6864-74. PubMed ID: 15615535
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Click chemistry on solid phase: parallel synthesis of N-benzyltriazole carboxamides as super-potent G-protein coupled receptor ligands.
    Loaiza PR; Löber S; Hübner H; Gmeiner P
    J Comb Chem; 2006; 8(2):252-61. PubMed ID: 16529521
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Virtual screening of biogenic amine-binding G-protein coupled receptors: comparative evaluation of protein- and ligand-based virtual screening protocols.
    Evers A; Hessler G; Matter H; Klabunde T
    J Med Chem; 2005 Aug; 48(17):5448-65. PubMed ID: 16107144
    [TBL] [Abstract][Full Text] [Related]  

  • 13. GPCR targeted library design: novel dopamine D3 receptor ligands.
    Böcker A; Sasse BC; Nietert M; Stark H; Schneider G
    ChemMedChem; 2007 Jul; 2(7):1000-5. PubMed ID: 17477344
    [No Abstract]   [Full Text] [Related]  

  • 14. Structural diversity of G protein-coupled receptors and significance for drug discovery.
    Lagerström MC; Schiöth HB
    Nat Rev Drug Discov; 2008 Apr; 7(4):339-57. PubMed ID: 18382464
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Generalization of a targeted library design protocol: application to 5-HT7 receptor ligands.
    Nordling E; Homan E
    J Chem Inf Comput Sci; 2004; 44(6):2207-15. PubMed ID: 15554691
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Sequence-derived three-dimensional pharmacophore models for G-protein-coupled receptors and their application in virtual screening.
    Klabunde T; Giegerich C; Evers A
    J Med Chem; 2009 May; 52(9):2923-32. PubMed ID: 19374402
    [TBL] [Abstract][Full Text] [Related]  

  • 17. From astemizole to a novel hit series of small-molecule somatostatin 5 receptor antagonists via GPCR affinity profiling.
    Guba W; Green LG; Martin RE; Roche O; Kratochwil N; Mauser H; Bissantz C; Christ A; Stahl M
    J Med Chem; 2007 Dec; 50(25):6295-8. PubMed ID: 18020391
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Focused library design in GPCR projects on the example of 5-HT(2c) agonists: comparison of structure-based virtual screening with ligand-based search methods.
    Bissantz C; Schalon C; Guba W; Stahl M
    Proteins; 2005 Dec; 61(4):938-52. PubMed ID: 16224780
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design and synthesis of a G-protein-coupled receptor antagonist library of aryloxyalkanolamines using a polymer-supported acyclic acetal linker.
    Roberge JY; Harikrishnan LS; Kamau MG; Ruan Z; Van Kirk K; Liu Y; Cooper CB; Poss MA; Dickson JK; Gavai AV; Chao ST; Leith LW; Bednarz MS; Mathur A; Kakarla R; Schnur DM; Vaz R; Lawrence RM
    J Comb Chem; 2009; 11(1):72-82. PubMed ID: 19086798
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ligand-based combinatorial design of selective purinergic receptor (A2A) antagonists using self-organizing maps.
    Schneider G; Nettekoven M
    J Comb Chem; 2003; 5(3):233-7. PubMed ID: 12739938
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.