206 related articles for article (PubMed ID: 1533576)
1. Novel diazinone derivatives separate myofilament Ca2+ sensitization and phosphodiesterase III inhibitory effects in guinea pig myocardium.
Ventura C; Miller R; Wolf HP; Beier N; Jonas R; Klockow M; Lues I; Hano O; Spurgeon HA; Lakatta EG
Circ Res; 1992 Jun; 70(6):1081-90. PubMed ID: 1533576
[TBL] [Abstract][Full Text] [Related]
2. A novel positive inotropic substance enhances contractility without increasing the Ca2+ transient in rat myocardium.
Ferroni C; Hano O; Ventura C; Lakatta EG; Klockow M; Spurgeon H; Capogrossi MC
J Mol Cell Cardiol; 1991 Mar; 23(3):325-31. PubMed ID: 1880816
[TBL] [Abstract][Full Text] [Related]
3. The two mechanisms of action of racemic cardiotonic EMD 53998, calcium sensitization and phosphodiesterase inhibition, reside in different enantiomers.
Lues I; Beier N; Jonas R; Klockow M; Haeusler G
J Cardiovasc Pharmacol; 1993 Jun; 21(6):883-92. PubMed ID: 7687712
[TBL] [Abstract][Full Text] [Related]
4. Ca2+ sensitization in idiopathic dilated human myocardium. Differential in vitro effects of (+)-(5-methyl-6-phenyl)-1,3,5,6-tetrahydro-3,6-methano-1,5-benzodiazoci ne-2,4-dione, a novel purely Ca2+sensitizing agent, and (+)-5-(1-(3,4-dimethoxybenzoyl)-1,2,3,4-tetrahydroquinolin-6-yl)-6-meth yl-3, 6-dihydro-2H-1,3,4-thiadiazin-2-one on skinned fibres and isolated ventricular strips.
Herzig JW; Chiesi M; Depersin H; Grüninger S; Hasenfuss G; Kubalek R; Leutert T; Pieske B; Pioch K; Wenk P; Holubarsch C
Arzneimittelforschung; 1996 Jun; 46(6):586-93. PubMed ID: 8767348
[TBL] [Abstract][Full Text] [Related]
5. The novel cardiotonic agent EMD 53 998 is a potent "calcium sensitizer".
Beier N; Harting J; Jonas R; Klockow M; Lues I; Haeusler G
J Cardiovasc Pharmacol; 1991 Jul; 18(1):17-27. PubMed ID: 1719287
[TBL] [Abstract][Full Text] [Related]
6. Stereoselective actions of thiadiazinones on canine cardiac myocytes and myofilaments.
Solaro RJ; Gambassi G; Warshaw DM; Keller MR; Spurgeon HA; Beier N; Lakatta EG
Circ Res; 1993 Dec; 73(6):981-90. PubMed ID: 8222092
[TBL] [Abstract][Full Text] [Related]
7. Differential effects of the optical isomers of EMD 53998 on contraction and cytoplasmic Ca2+ in isolated ferret cardiac muscle.
White J; Lee JA; Shah N; Orchard CH
Circ Res; 1993 Jul; 73(1):61-70. PubMed ID: 8508534
[TBL] [Abstract][Full Text] [Related]
8. Enantiomeric dissection of the effects of the inotropic agent, EMD 53998, in single cardiac myocytes.
Gambassi G; Capogrossi MC; Klockow M; Lakatta EG
Am J Physiol; 1993 Mar; 264(3 Pt 2):H728-38. PubMed ID: 8384421
[TBL] [Abstract][Full Text] [Related]
9. In vivo evidence of positive inotropism of EMD 57033 through calcium sensitization.
Haeusler G; Jonas R; Minck KO; Schliep HJ; Schelling P; Weygandt H; Lues I
J Cardiovasc Pharmacol; 1997 May; 29(5):647-55. PubMed ID: 9213208
[TBL] [Abstract][Full Text] [Related]
10. The effect of a thiadiazinone derived Ca2+ sensitizer on the responsiveness of Mg(2+)-ATPase to Ca2+ in myofibrils isolated from stunned and nonstunned porcine and human myocardium.
Bezstarosti K; Soei LK; Krams R; Ten Cate FJ; Verdouw PD; Lamers JM
Biochem Pharmacol; 1996 May; 51(9):1211-20. PubMed ID: 8645345
[TBL] [Abstract][Full Text] [Related]
11. EMD 53998 acts as Ca(2+)-sensitizer and phosphodiesterase III-inhibitor in human myocardium.
Uhlmann R; Schwinger RH; Lues I; Erdmann E
Basic Res Cardiol; 1995; 90(5):365-71. PubMed ID: 8585857
[TBL] [Abstract][Full Text] [Related]
12. The positive inotropic calcium sensitizer EMD 53998 antagonizes phosphate action on cross-bridges in cardiac skinned fibers.
Strauss JD; Zeugner C; Rüegg JC
Eur J Pharmacol; 1992 Dec; 227(4):437-41. PubMed ID: 1446713
[TBL] [Abstract][Full Text] [Related]
13. Effects of Ca2+ sensitizers on contraction, [Ca2+]i transient and myofilament Ca2+ sensitivity in diabetic rat myocardium: potential usefulness as inotropic agents.
Ishitani T; Hattori Y; Sakuraya F; Onozuka H; Makino T; Matsuda N; Gando S; Kemmotsu O
J Pharmacol Exp Ther; 2001 Aug; 298(2):613-22. PubMed ID: 11454923
[TBL] [Abstract][Full Text] [Related]
14. CGP-48506 increases contractility of ventricular myocytes and myofilaments by effects on actin-myosin reaction.
Wolska BM; Kitada Y; Palmiter KA; Westfall MV; Johnson MD; Solaro RJ
Am J Physiol; 1996 Jan; 270(1 Pt 2):H24-32. PubMed ID: 8769730
[TBL] [Abstract][Full Text] [Related]
15. Effects of EMD 57033 on contraction and relaxation in isolated rabbit hearts.
Hgashiyama A; Watkins MW; Chen Z; LeWinter MM
Circulation; 1995 Nov; 92(10):3094-104. PubMed ID: 7586281
[TBL] [Abstract][Full Text] [Related]
16. Effects of calcium sensitizers on intracellular calcium handling and myocardial energetics.
Hasenfuss G; Pieske B; Kretschmann B; Holubarsch C; Alpert NR; Just H
J Cardiovasc Pharmacol; 1995; 26 Suppl 1():S45-51. PubMed ID: 8907130
[TBL] [Abstract][Full Text] [Related]
17. Cardiovascular effects of the novel Ca2+-sensitiser EMD 57033 in pigs at rest and during treadmill exercise.
Stubenitsky R; van der Weerd RW; Haitsma DB; Verdouw PD; Duncker DJ
Br J Pharmacol; 1997 Dec; 122(7):1257-70. PubMed ID: 9421271
[TBL] [Abstract][Full Text] [Related]
18. EMD 53998 sensitizes the contractile proteins to calcium in intact ferret ventricular muscle.
Lee JA; Allen DG
Circ Res; 1991 Oct; 69(4):927-36. PubMed ID: 1934345
[TBL] [Abstract][Full Text] [Related]
19. Different chronotropic and inotropic effects of EMD 57033 and EMD 53998, Ca2+ sensitizers, on isolated, blood-perfused dog heart preparations.
Lakhe M; Furukawa Y; Yonezawa T; Hirose M; Nagashima Y; Miyashita Y; Chiba S
Jpn J Pharmacol; 1998 Apr; 76(4):435-9. PubMed ID: 9623723
[TBL] [Abstract][Full Text] [Related]
20. Sensitization of dog and guinea pig heart myofilaments to Ca2+ activation and the inotropic effect of pimobendan: comparison with milrinone.
Fujino K; Sperelakis N; Solaro RJ
Circ Res; 1988 Nov; 63(5):911-22. PubMed ID: 2846200
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]