These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

175 related articles for article (PubMed ID: 15338951)

  • 1. Microwave-enhanced medicinal chemistry: a high-speed opportunity for convenient preparation of protease inhibitors.
    Ersmark K; Larhed M; Wannberg J
    Curr Opin Drug Discov Devel; 2004 Jul; 7(4):417-27. PubMed ID: 15338951
    [TBL] [Abstract][Full Text] [Related]  

  • 2. High-speed optimization of inhibitors of the malarial proteases plasmepsin I and II.
    Nöteberg D; Schaal W; Hamelink E; Vrang L; Larhed M
    J Comb Chem; 2003; 5(4):456-64. PubMed ID: 12857114
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C.
    Gising J; Odell LR; Larhed M
    Org Biomol Chem; 2012 Apr; 10(14):2713-29. PubMed ID: 22227602
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High-speed synthesis of potent C2-symmetric HIV-1 protease inhibitors by in-situ aminocarbonylations.
    Wannberg J; Kaiser NF; Vrang L; Samuelsson B; Larhed M; Hallberg A
    J Comb Chem; 2005; 7(4):611-7. PubMed ID: 16004505
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design of new plasmepsin inhibitors: a virtual high throughput screening approach on the EGEE grid.
    Kasam V; Zimmermann M; Maass A; Schwichtenberg H; Wolf A; Jacq N; Breton V; Hofmann-Apitius M
    J Chem Inf Model; 2007; 47(5):1818-28. PubMed ID: 17727268
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The impact of microwave synthesis on drug discovery.
    Kappe CO; Dallinger D
    Nat Rev Drug Discov; 2006 Jan; 5(1):51-63. PubMed ID: 16374514
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Recent applications of microwave irradiation to medicinal chemistry.
    Alcázar J; Oehlrich D
    Future Med Chem; 2010 Feb; 2(2):169-76. PubMed ID: 21426184
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design and synthesis of plasmepsin I and plasmepsin II inhibitors with activity in Plasmodium falciparum-infected cultured human erythrocytes.
    Nöteberg D; Hamelink E; Hultén J; Wahlgren M; Vrang L; Samuelsson B; Hallberg A
    J Med Chem; 2003 Feb; 46(5):734-46. PubMed ID: 12593654
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and activity of tetrapeptidic HTLV-I protease inhibitors possessing different P3-cap moieties.
    Zhang M; Nguyen JT; Kumada HO; Kimura T; Cheng M; Hayashi Y; Kiso Y
    Bioorg Med Chem; 2008 May; 16(10):5795-802. PubMed ID: 18400502
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A new structural theme in C2-symmetric HIV-1 protease inhibitors: ortho-substituted P1/P1' side chains.
    Wannberg J; Sabnis YA; Vrang L; Samuelsson B; Karlén A; Hallberg A; Larhed M
    Bioorg Med Chem; 2006 Aug; 14(15):5303-15. PubMed ID: 16621572
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Easy-to-execute carbonylations: microwave synthesis of acyl sulfonamides using Mo(CO)(6) as a solid carbon monoxide source.
    Wu X; Rönn R; Gossas T; Larhed M
    J Org Chem; 2005 Apr; 70(8):3094-8. PubMed ID: 15822969
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Microwave-accelerated synthesis of P1'-extended HIV-1 protease inhibitors encompassing a tertiary alcohol in the transition-state mimicking scaffold.
    Ekegren JK; Ginman N; Johansson A; Wallberg H; Larhed M; Samuelsson B; Unge T; Hallberg A
    J Med Chem; 2006 Mar; 49(5):1828-32. PubMed ID: 16509598
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Achiral oligoamines as versatile tool for the development of aspartic protease inhibitors.
    Blum A; Böttcher J; Sammet B; Luksch T; Heine A; Klebe G; Diederich WE
    Bioorg Med Chem; 2008 Sep; 16(18):8574-86. PubMed ID: 18760609
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates.
    Liang FS; Brik A; Lin YC; Elder JH; Wong CH
    Bioorg Med Chem; 2006 Feb; 14(4):1058-62. PubMed ID: 16275107
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel nonpeptidic inhibitors of HIV-1 protease obtained via a new multicomponent chemistry strategy.
    Yehia NA; Antuch W; Beck B; Hess S; Schauer-Vukasinović V; Almstetter M; Furer P; Herdtweck E; Dömling A
    Bioorg Med Chem Lett; 2004 Jun; 14(12):3121-5. PubMed ID: 15149657
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Design of inhibitors against HIV, HTLV-I, and Plasmodium falciparum aspartic proteases.
    Abdel-Rahman HM; Kimura T; Hidaka K; Kiso A; Nezami A; Freire E; Hayashi Y; Kiso Y
    Biol Chem; 2004 Nov; 385(11):1035-9. PubMed ID: 15576323
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The potential of P1 site alterations in peptidomimetic protease inhibitors as suggested by virtual screening and explored by the use of C-C-coupling reagents.
    Weik S; Luksch T; Evers A; Böttcher J; Sotriffer CA; Hasilik A; Löffler HG; Klebe G; Rademann J
    ChemMedChem; 2006 Apr; 1(4):445-57. PubMed ID: 16892380
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Toward rapid, "green", predictable microwave-assisted synthesis.
    Roberts BA; Strauss CR
    Acc Chem Res; 2005 Aug; 38(8):653-61. PubMed ID: 16104688
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Macrocyclic inhibitors of the malarial aspartic proteases plasmepsin I, II, and IV.
    Ersmark K; Nervall M; Gutiérrez-de-Terán H; Hamelink E; Janka LK; Clemente JC; Dunn BM; Gogoll A; Samuelsson B; Qvist J; Hallberg A
    Bioorg Med Chem; 2006 Apr; 14(7):2197-208. PubMed ID: 16307884
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Lysine derivatives as potent HIV protease inhibitors. Discovery, synthesis and structure-activity relationship studies.
    Bouzide A; Sauvé G; Yelle J
    Bioorg Med Chem Lett; 2005 Mar; 15(5):1509-13. PubMed ID: 15713418
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.