226 related articles for article (PubMed ID: 15341734)
1. Crystal structure of 7,8-dihydropteroate synthase from Bacillus anthracis: mechanism and novel inhibitor design.
Babaoglu K; Qi J; Lee RE; White SW
Structure; 2004 Sep; 12(9):1705-17. PubMed ID: 15341734
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action.
Baca AM; Sirawaraporn R; Turley S; Sirawaraporn W; Hol WG
J Mol Biol; 2000 Oct; 302(5):1193-212. PubMed ID: 11007651
[TBL] [Abstract][Full Text] [Related]
3. Dihydropteroate synthase from Streptococcus pneumoniae: structure, ligand recognition and mechanism of sulfonamide resistance.
Levy C; Minnis D; Derrick JP
Biochem J; 2008 Jun; 412(2):379-88. PubMed ID: 18321242
[TBL] [Abstract][Full Text] [Related]
4. Crystal structure of the anthrax drug target, Bacillus anthracis dihydrofolate reductase.
Bennett BC; Xu H; Simmerman RF; Lee RE; Dealwis CG
J Med Chem; 2007 Sep; 50(18):4374-81. PubMed ID: 17696333
[TBL] [Abstract][Full Text] [Related]
5. Structural studies of pterin-based inhibitors of dihydropteroate synthase.
Hevener KE; Yun MK; Qi J; Kerr ID; Babaoglu K; Hurdle JG; Balakrishna K; White SW; Lee RE
J Med Chem; 2010 Jan; 53(1):166-77. PubMed ID: 19899766
[TBL] [Abstract][Full Text] [Related]
6. Structure-based design of a potent and selective small peptide inhibitor of Mycobacterium tuberculosis 6-hydroxymethyl-7, 8-dihydropteroate synthase: a computer modelling approach.
Rao GS; Kumar M
Chem Biol Drug Des; 2008 Jun; 71(6):540-5. PubMed ID: 18482337
[TBL] [Abstract][Full Text] [Related]
7. Elucidation of sulfadoxine resistance with structural models of the bifunctional Plasmodium falciparum dihydropterin pyrophosphokinase-dihydropteroate synthase.
de Beer TA; Louw AI; Joubert F
Bioorg Med Chem; 2006 Jul; 14(13):4433-43. PubMed ID: 16517168
[TBL] [Abstract][Full Text] [Related]
8. Crystal structures of Burkholderia cenocepacia dihydropteroate synthase in the apo-form and complexed with the product 7,8-dihydropteroate.
Morgan RE; Batot GO; Dement JM; Rao VA; Eadsforth TC; Hunter WN
BMC Struct Biol; 2011 May; 11():21. PubMed ID: 21554707
[TBL] [Abstract][Full Text] [Related]
9. The three-dimensional structure of the bifunctional 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase/dihydropteroate synthase of Saccharomyces cerevisiae.
Lawrence MC; Iliades P; Fernley RT; Berglez J; Pilling PA; Macreadie IG
J Mol Biol; 2005 May; 348(3):655-70. PubMed ID: 15826662
[TBL] [Abstract][Full Text] [Related]
10. Biochemical and structural characterization of the putative dihydropteroate synthase ortholog Rv1207 of Mycobacterium tuberculosis.
Gengenbacher M; Xu T; Niyomrattanakit P; Spraggon G; Dick T
FEMS Microbiol Lett; 2008 Oct; 287(1):128-35. PubMed ID: 18680522
[TBL] [Abstract][Full Text] [Related]
11. Examination of intrinsic sulfonamide resistance in Bacillus anthracis: a novel assay for dihydropteroate synthase.
Valderas MW; Andi B; Barrow WW; Cook PF
Biochim Biophys Acta; 2008 May; 1780(5):848-53. PubMed ID: 18342015
[TBL] [Abstract][Full Text] [Related]
12. Development of a pterin-based fluorescent probe for screening dihydropteroate synthase.
Zhao Y; Hammoudeh D; Lin W; Das S; Yun MK; Li Z; Griffith E; Chen T; White SW; Lee RE
Bioconjug Chem; 2011 Oct; 22(10):2110-7. PubMed ID: 21916405
[TBL] [Abstract][Full Text] [Related]
13. Structural adaptation of an interacting non-native C-terminal helical extension revealed in the crystal structure of NAD+ synthetase from Bacillus anthracis.
McDonald HM; Pruett PS; Deivanayagam C; Protasevich II; Carson WM; DeLucas LJ; Brouillette WJ; Brouillette CG
Acta Crystallogr D Biol Crystallogr; 2007 Aug; 63(Pt 8):891-905. PubMed ID: 17642516
[TBL] [Abstract][Full Text] [Related]
14. Structure-based design of novel pyrimido[4,5-c]pyridazine derivatives as dihydropteroate synthase inhibitors with increased affinity.
Zhao Y; Hammoudeh D; Yun MK; Qi J; White SW; Lee RE
ChemMedChem; 2012 May; 7(5):861-70. PubMed ID: 22416048
[TBL] [Abstract][Full Text] [Related]
15. 8-Mercaptoguanine Derivatives as Inhibitors of Dihydropteroate Synthase.
Dennis ML; Lee MD; Harjani JR; Ahmed M; DeBono AJ; Pitcher NP; Wang ZC; Chhabra S; Barlow N; Rahmani R; Cleary B; Dolezal O; Hattarki M; Aurelio L; Shonberg J; Graham B; Peat TS; Baell JB; Swarbrick JD
Chemistry; 2018 Feb; 24(8):1922-1930. PubMed ID: 29171692
[TBL] [Abstract][Full Text] [Related]
16. Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents.
Zhao Y; Shadrick WR; Wallace MJ; Wu Y; Griffith EC; Qi J; Yun MK; White SW; Lee RE
Bioorg Med Chem Lett; 2016 Aug; 26(16):3950-4. PubMed ID: 27423480
[TBL] [Abstract][Full Text] [Related]
17. Dihydropteroate synthase from Streptococcus pneumoniae: characterization of substrate binding order and sulfonamide inhibition.
Vinnicombe HG; Derrick JP
Biochem Biophys Res Commun; 1999 May; 258(3):752-7. PubMed ID: 10329458
[TBL] [Abstract][Full Text] [Related]
18. Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding.
Kosinska U; Carnrot C; Sandrini MP; Clausen AR; Wang L; Piskur J; Eriksson S; Eklund H
FEBS J; 2007 Feb; 274(3):727-37. PubMed ID: 17288553
[TBL] [Abstract][Full Text] [Related]
19. Crystal structure of Bacillus anthracis ThiI, a tRNA-modifying enzyme containing the predicted RNA-binding THUMP domain.
Waterman DG; Ortiz-LombardÃa M; Fogg MJ; Koonin EV; Antson AA
J Mol Biol; 2006 Feb; 356(1):97-110. PubMed ID: 16343540
[TBL] [Abstract][Full Text] [Related]
20. Genetic basis for sulfonamide resistance in Bacillus anthracis.
Valderas MW; Bourne PC; Barrow WW
Microb Drug Resist; 2007; 13(1):11-20. PubMed ID: 17536929
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]