177 related articles for article (PubMed ID: 15341931)
1. Novel pyrazinone inhibitors of mast cell tryptase: synthesis and SAR evaluation.
Hopkins C; Neuenschwander K; Scotese A; Jackson S; Nieduzak T; Pauls H; Liang G; Sides K; Cramer D; Cairns J; Maignan S; Mathieu M
Bioorg Med Chem Lett; 2004 Oct; 14(19):4819-23. PubMed ID: 15341931
[TBL] [Abstract][Full Text] [Related]
2. Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors.
Sutton JC; Bolton SA; Davis ME; Hartl KS; Jacobson B; Mathur A; Ogletree ML; Slusarchyk WA; Zahler R; Seiler SM; Bisacchi GS
Bioorg Med Chem Lett; 2004 May; 14(9):2233-9. PubMed ID: 15081015
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and evaluation of 4-substituted benzylamine derivatives as beta-tryptase inhibitors.
Miyazaki Y; Kato Y; Manabe T; Shimada H; Mizuno M; Egusa T; Ohkouchi M; Shiromizu I; Matsusue T; Yamamoto I
Bioorg Med Chem Lett; 2006 Jun; 16(11):2986-90. PubMed ID: 16540315
[TBL] [Abstract][Full Text] [Related]
4. Synthesis of potent and highly selective nonguanidine azetidinone inhibitors of human tryptase.
Bisacchi GS; Slusarchyk WA; Bolton SA; Hartl KS; Jacobs G; Mathur A; Meng W; Ogletree ML; Pi Z; Sutton JC; Treuner U; Zahler R; Zhao G; Seiler SM
Bioorg Med Chem Lett; 2004 May; 14(9):2227-31. PubMed ID: 15081014
[TBL] [Abstract][Full Text] [Related]
5. Combinatorial approaches towards the discovery of new tryptase inhibitors.
del Fresno M; Fernández-Forner D; Miralpeix M; Segarra V; Ryder H; Royo M; Albericio F
Bioorg Med Chem Lett; 2005 Mar; 15(6):1659-64. PubMed ID: 15745817
[TBL] [Abstract][Full Text] [Related]
6. Neutrophil myeloperoxidase is a potent and selective inhibitor of mast cell tryptase.
Cregar L; Elrod KC; Putnam D; Moore WR
Arch Biochem Biophys; 1999 Jun; 366(1):125-30. PubMed ID: 10334872
[TBL] [Abstract][Full Text] [Related]
7. Design, parallel synthesis, and crystal structures of pyrazinone antithrombotics as selective inhibitors of the tissue factor VIIa complex.
Parlow JJ; Case BL; Dice TA; Fenton RL; Hayes MJ; Jones DE; Neumann WL; Wood RS; Lachance RM; Girard TJ; Nicholson NS; Clare M; Stegeman RA; Stevens AM; Stallings WC; Kurumbail RG; South MS
J Med Chem; 2003 Sep; 46(19):4050-62. PubMed ID: 12954058
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of human beta-tryptase by Bowman-Birk inhibitor derived peptides: creation of a new tri-functional inhibitor.
Scarpi D; McBride JD; Leatherbarrow RJ
Bioorg Med Chem; 2004 Dec; 12(23):6045-52. PubMed ID: 15519150
[TBL] [Abstract][Full Text] [Related]
9. Design, synthesis, and biological activity of potent and selective inhibitors of mast cell tryptase.
Hopkins CR; Czekaj M; Kaye SS; Gao Z; Pribish J; Pauls H; Liang G; Sides K; Cramer D; Cairns J; Luo Y; Lim HK; Vaz R; Rebello S; Maignan S; Dupuy A; Mathieu M; Levell J
Bioorg Med Chem Lett; 2005 Jun; 15(11):2734-7. PubMed ID: 15911249
[TBL] [Abstract][Full Text] [Related]
10. 1,2,5-Thiadiazolidin-3-one 1,1-dioxide-based heterocyclic sulfides are potent inhibitors of human tryptase.
Wong T; Groutas CS; Mohan S; Lai Z; Alliston KR; Vu N; Schechter NM; Groutas WC
Arch Biochem Biophys; 2005 Apr; 436(1):1-7. PubMed ID: 15752703
[TBL] [Abstract][Full Text] [Related]
11. Novel, potent, selective, and orally bioavailable human betaII-tryptase inhibitors.
Sperandio D; Tai VW; Lohman J; Hirschbein B; Mendonca R; Lee CS; Spencer JR; Janc J; Nguyen M; Beltman J; Sprengeler P; Scheerens H; Lin T; Liu L; Gadre A; Kellogg A; Green MJ; McGrath ME
Bioorg Med Chem Lett; 2006 Aug; 16(15):4085-9. PubMed ID: 16725321
[TBL] [Abstract][Full Text] [Related]
12. Structure-guided design of peptide-based tryptase inhibitors.
McGrath ME; Sprengeler PA; Hirschbein B; Somoza JR; Lehoux I; Janc JW; Gjerstad E; Graupe M; Estiarte A; Venkataramani C; Liu Y; Yee R; Ho JD; Green MJ; Lee CS; Liu L; Tai V; Spencer J; Sperandio D; Katz BA
Biochemistry; 2006 May; 45(19):5964-73. PubMed ID: 16681368
[TBL] [Abstract][Full Text] [Related]
13. 1,2-Benzisothiazol-3-one 1,1-dioxide inhibitors of human mast cell tryptase.
Combrink KD; Gülgeze HB; Meanwell NA; Pearce BC; Zulan P; Bisacchi GS; Roberts DG; Stanley P; Seiler SM
J Med Chem; 1998 Nov; 41(24):4854-60. PubMed ID: 9822554
[TBL] [Abstract][Full Text] [Related]
14. Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone.
Costanzo MJ; Yabut SC; Almond HR; Andrade-Gordon P; Corcoran TW; De Garavilla L; Kauffman JA; Abraham WM; Recacha R; Chattopadhyay D; Maryanoff BE
J Med Chem; 2003 Aug; 46(18):3865-76. PubMed ID: 12930148
[TBL] [Abstract][Full Text] [Related]
15. Dibasic inhibitors of human mast cell tryptase. Part 1: synthesis and optimization of a novel class of inhibitors.
Rice KD; Gangloff AR; Kuo EY; Dener JM; Wang VR; Lum R; Newcomb WS; Havel C; Putnam D; Cregar L; Wong M; Warne RL
Bioorg Med Chem Lett; 2000 Oct; 10(20):2357-60. PubMed ID: 11055355
[TBL] [Abstract][Full Text] [Related]
16. Syntheses and evaluation of amidinobenzofuran derivatives as tryptase inhibitors.
Ono S; Kuwahara S; Takeuchi M; Sakashita H; Naito Y; Kondo T
Bioorg Med Chem Lett; 1999 Dec; 9(23):3285-90. PubMed ID: 10612586
[TBL] [Abstract][Full Text] [Related]
17. Pyrrolidinyl pyridone and pyrazinone analogues as potent inhibitors of prolyl oligopeptidase (POP).
Haffner CD; Diaz CJ; Miller AB; Reid RA; Madauss KP; Hassell A; Hanlon MH; Porter DJ; Becherer JD; Carter LH
Bioorg Med Chem Lett; 2008 Aug; 18(15):4360-3. PubMed ID: 18606544
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis and biological activity of a targeted library of potential tryptase inhibitors.
García M; del Rio X; Silvestre S; Rubiralta M; Lozoya E; Segarra V; Fernández D; Miralpeix M; Aparici M; Diez A
Org Biomol Chem; 2004 Jun; 2(11):1633-42. PubMed ID: 15162216
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of potent and highly selective inhibitors of human tryptase.
Slusarchyk WA; Bolton SA; Hartl KS; Huang MH; Jacobs G; Meng W; Ogletree ML; Pi Z; Schumacher WA; Seiler SM; Sutton JC; Treuner U; Zahler R; Zhao G; Bisacchi GS
Bioorg Med Chem Lett; 2002 Nov; 12(21):3235-8. PubMed ID: 12372541
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and evaluation of diphenyl phosphonate esters as inhibitors of the trypsin-like granzymes A and K and mast cell tryptase.
Jackson DS; Fraser SA; Ni LM; Kam CM; Winkler U; Johnson DA; Froelich CJ; Hudig D; Powers JC
J Med Chem; 1998 Jun; 41(13):2289-301. PubMed ID: 9632362
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
