225 related articles for article (PubMed ID: 15342248)
1. Crystal structure of human ABAD/HSD10 with a bound inhibitor: implications for design of Alzheimer's disease therapeutics.
Kissinger CR; Rejto PA; Pelletier LA; Thomson JA; Showalter RE; Abreo MA; Agree CS; Margosiak S; Meng JJ; Aust RM; Vanderpool D; Li B; Tempczyk-Russell A; Villafranca JE
J Mol Biol; 2004 Sep; 342(3):943-52. PubMed ID: 15342248
[TBL] [Abstract][Full Text] [Related]
2. Molecular dynamics simulations of the amyloid-beta binding alcohol dehydrogenase (ABAD) enzyme.
Marques AT; Fernandes PA; Ramos MJ
Bioorg Med Chem; 2008 Nov; 16(21):9511-8. PubMed ID: 18835182
[TBL] [Abstract][Full Text] [Related]
3. Hydroxysteroid (17β) dehydrogenase X in human health and disease.
Yang SY; He XY; Miller D
Mol Cell Endocrinol; 2011 Aug; 343(1-2):1-6. PubMed ID: 21708223
[TBL] [Abstract][Full Text] [Related]
4. Crystal structure of yeast peroxisomal multifunctional enzyme: structural basis for substrate specificity of (3R)-hydroxyacyl-CoA dehydrogenase units.
Ylianttila MS; Pursiainen NV; Haapalainen AM; Juffer AH; Poirier Y; Hiltunen JK; Glumoff T
J Mol Biol; 2006 May; 358(5):1286-95. PubMed ID: 16574148
[TBL] [Abstract][Full Text] [Related]
5. Comparative evolutionary genomics of the HADH2 gene encoding Abeta-binding alcohol dehydrogenase/17beta-hydroxysteroid dehydrogenase type 10 (ABAD/HSD10).
Marques AT; Antunes A; Fernandes PA; Ramos MJ
BMC Genomics; 2006 Aug; 7():202. PubMed ID: 16899120
[TBL] [Abstract][Full Text] [Related]
6. Biochemical characterization and crystal structure determination of human heart short chain L-3-hydroxyacyl-CoA dehydrogenase provide insights into catalytic mechanism.
Barycki JJ; O'Brien LK; Bratt JM; Zhang R; Sanishvili R; Strauss AW; Banaszak LJ
Biochemistry; 1999 May; 38(18):5786-98. PubMed ID: 10231530
[TBL] [Abstract][Full Text] [Related]
7. Recognition of structurally diverse substrates by type II 3-hydroxyacyl-CoA dehydrogenase (HADH II)/amyloid-beta binding alcohol dehydrogenase (ABAD).
Powell AJ; Read JA; Banfield MJ; Gunn-Moore F; Yan SD; Lustbader J; Stern AR; Stern DM; Brady RL
J Mol Biol; 2000 Oct; 303(2):311-27. PubMed ID: 11023795
[TBL] [Abstract][Full Text] [Related]
8. Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment.
Hroch L; Benek O; Guest P; Aitken L; Soukup O; Janockova J; Musil K; Dohnal V; Dolezal R; Kuca K; Smith TK; Gunn-Moore F; Musilek K
Bioorg Med Chem Lett; 2016 Aug; 26(15):3675-8. PubMed ID: 27287370
[TBL] [Abstract][Full Text] [Related]
9. Identification of small-molecule inhibitors of the Abeta-ABAD interaction.
Xie Y; Deng S; Chen Z; Yan S; Landry DW
Bioorg Med Chem Lett; 2006 Sep; 16(17):4657-60. PubMed ID: 16781151
[TBL] [Abstract][Full Text] [Related]
10. Multiple functions of type 10 17beta-hydroxysteroid dehydrogenase.
Yang SY; He XY; Schulz H
Trends Endocrinol Metab; 2005; 16(4):167-75. PubMed ID: 15860413
[TBL] [Abstract][Full Text] [Related]
11. Synthesis and evaluation of frentizole-based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer's disease treatment.
Hroch L; Guest P; Benek O; Soukup O; Janockova J; Dolezal R; Kuca K; Aitken L; Smith TK; Gunn-Moore F; Zala D; Ramsay RR; Musilek K
Bioorg Med Chem; 2017 Feb; 25(3):1143-1152. PubMed ID: 28082069
[TBL] [Abstract][Full Text] [Related]
12. Surface plasmon resonance and nuclear magnetic resonance studies of ABAD-Abeta interaction.
Yan Y; Liu Y; Sorci M; Belfort G; Lustbader JW; Yan SS; Wang C
Biochemistry; 2007 Feb; 46(7):1724-31. PubMed ID: 17253767
[TBL] [Abstract][Full Text] [Related]
13. Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment.
Schmidt M; Benek O; Vinklarova L; Hrabinova M; Zemanova L; Chribek M; Kralova V; Hroch L; Dolezal R; Lycka A; Prchal L; Jun D; Aitken L; Gunn-Moore F; Kuca K; Musilek K
Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32192199
[TBL] [Abstract][Full Text] [Related]
14. [Mitochondrial enzyme ABAD and its role in the development and treatment of Alzheimer's disease].
Benek O; Musílek K; Kuca K
Ceska Slov Farm; 2012 Aug; 61(4):144-9. PubMed ID: 23251955
[TBL] [Abstract][Full Text] [Related]
15. Crystal structure and amide H/D exchange of binary complexes of alcohol dehydrogenase from Bacillus stearothermophilus: insight into thermostability and cofactor binding.
Ceccarelli C; Liang ZX; Strickler M; Prehna G; Goldstein BM; Klinman JP; Bahnson BJ
Biochemistry; 2004 May; 43(18):5266-77. PubMed ID: 15122892
[TBL] [Abstract][Full Text] [Related]
16. Roles of Mitochondrial 17β-Hydroxysteroid Dehydrogenase Type 10 in Alzheimer's Disease.
He XY; Isaacs C; Yang SY
J Alzheimers Dis; 2018; 62(2):665-673. PubMed ID: 29480196
[TBL] [Abstract][Full Text] [Related]
17. Expression and purification of His-tagged rat mitochondrial short-chain 3-hydroxyacyl-CoA dehydrogenase wild-type and Ser137 mutant proteins.
Liu X; Chu X; Yu W; Li P; Li D
Protein Expr Purif; 2004 Oct; 37(2):344-51. PubMed ID: 15358356
[TBL] [Abstract][Full Text] [Related]
18. 3-Hydroxyacyl-CoA dehydrogenase and short chain 3-hydroxyacyl-CoA dehydrogenase in human health and disease.
Yang SY; He XY; Schulz H
FEBS J; 2005 Oct; 272(19):4874-83. PubMed ID: 16176262
[TBL] [Abstract][Full Text] [Related]
19. ABAD: a potential therapeutic target for Abeta-induced mitochondrial dysfunction in Alzheimer's disease.
Marques AT; Fernandes PA; Ramos MJ
Mini Rev Med Chem; 2009 Jul; 9(8):1002-8. PubMed ID: 19601895
[TBL] [Abstract][Full Text] [Related]
20. Harnessing functional plasticity of enzymes: a fluorogenic probe for imaging 17beta-HSD10 dehydrogenase, an enzyme involved in Alzheimer's and Parkinson's diseases.
Froemming MK; Sames D
J Am Chem Soc; 2007 Nov; 129(46):14518-22. PubMed ID: 17958419
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]