BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

161 related articles for article (PubMed ID: 15342418)

  • 1. P21Cip1 is a critical mediator of the cytotoxic action of thymidylate synthase inhibitors in colorectal carcinoma cells.
    Geller JI; Szekely-Szucs K; Petak I; Doyle B; Houghton JA
    Cancer Res; 2004 Sep; 64(17):6296-303. PubMed ID: 15342418
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Interferon-gamma-induced sensitization of colon carcinomas to ZD9331 targets caspases, downstream of Fas, independent of mitochondrial signaling and the inhibitor of apoptosis survivin.
    Geller J; Petak I; Szucs KS; Nagy K; Tillman DM; Houghton JA
    Clin Cancer Res; 2003 Dec; 9(17):6504-15. PubMed ID: 14695155
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.
    Yin MB; Guo B; Panadero A; Frank C; Wrzosek C; Slocum HK; Rustum YM
    Exp Cell Res; 1999 Feb; 247(1):189-99. PubMed ID: 10047461
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Serine/threonine protein phosphatase inhibition enhances the effect of thymidylate synthase inhibition.
    Sakoff JA; Howitt IJ; Ackland SP; McCluskey A
    Cancer Chemother Pharmacol; 2004 Mar; 53(3):225-32. PubMed ID: 14648018
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interferon-alpha-induced G1 phase arrest through up-regulated expression of CDK inhibitors, p19Ink4D and p21Cip1 in mouse macrophages.
    Matsuoka M; Tani K; Asano S
    Oncogene; 1998 Apr; 16(16):2075-86. PubMed ID: 9572488
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA damage and p53 induction do not cause ZD1694-induced cell cycle arrest in human colon carcinoma cells.
    Matsui SI; Arredondo MA; Wrzosek C; Rustum YM
    Cancer Res; 1996 Oct; 56(20):4715-23. PubMed ID: 8840989
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Deregulation of p53/p21Cip1/Waf1 pathway contributes to polyploidy and apoptosis of E1A+cHa-ras transformed cells after gamma-irradiation.
    Bulavin DV; Tararova ND; Aksenov ND; Pospelov VA; Pospelova TV
    Oncogene; 1999 Oct; 18(41):5611-9. PubMed ID: 10523840
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Fas-dependent component in 5-fluorouracil/leucovorin-induced cytotoxicity in colon carcinoma cells.
    Tillman DM; Petak I; Houghton JA
    Clin Cancer Res; 1999 Feb; 5(2):425-30. PubMed ID: 10037193
    [TBL] [Abstract][Full Text] [Related]  

  • 9. UVB radiation induces p21Cip1/WAF1 and mediates G1 and S phase checkpoints.
    Petrocelli T; Poon R; Drucker DJ; Slingerland JM; Rosen CF
    Oncogene; 1996 Apr; 12(7):1387-96. PubMed ID: 8622854
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p53/p21(CIP1) cooperate in enforcing rapamycin-induced G(1) arrest and determine the cellular response to rapamycin.
    Huang S; Liu LN; Hosoi H; Dilling MB; Shikata T; Houghton PJ
    Cancer Res; 2001 Apr; 61(8):3373-81. PubMed ID: 11309295
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phenoxodiol, a novel isoflavone, induces G1 arrest by specific loss in cyclin-dependent kinase 2 activity by p53-independent induction of p21WAF1/CIP1.
    Aguero MF; Facchinetti MM; Sheleg Z; Senderowicz AM
    Cancer Res; 2005 Apr; 65(8):3364-73. PubMed ID: 15833870
    [TBL] [Abstract][Full Text] [Related]  

  • 12. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
    Akiyama T; Yoshida T; Tsujita T; Shimizu M; Mizukami T; Okabe M; Akinaga S
    Cancer Res; 1997 Apr; 57(8):1495-501. PubMed ID: 9108451
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tetrandrine induces early G1 arrest in human colon carcinoma cells by down-regulating the activity and inducing the degradation of G1-S-specific cyclin-dependent kinases and by inducing p53 and p21Cip1.
    Meng LH; Zhang H; Hayward L; Takemura H; Shao RG; Pommier Y
    Cancer Res; 2004 Dec; 64(24):9086-92. PubMed ID: 15604277
    [TBL] [Abstract][Full Text] [Related]  

  • 14. F9 embryonal carcinoma cells fail to stop at G1/S boundary of the cell cycle after gamma-irradiation due to p21WAF1/CIP1 degradation.
    Malashicheva AB; Kislyakova TV; Aksenov ND; Osipov KA; Pospelov VA
    Oncogene; 2000 Aug; 19(34):3858-65. PubMed ID: 10951579
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of the melanoma cell cycle and regulation at the G1/S transition by 12-O-tetradecanoylphorbol-13-acetate (TPA) by modulation of CDK2 activity.
    Coppock DL; Buffolino P; Kopman C; Nathanson L
    Exp Cell Res; 1995 Nov; 221(1):92-102. PubMed ID: 7589260
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Enhanced sensitivity to irinotecan by Cdk1 inhibition in the p53-deficient HT29 human colon cancer cell line.
    Abal M; Bras-Goncalves R; Judde JG; Fsihi H; De Cremoux P; Louvard D; Magdelenat H; Robine S; Poupon MF
    Oncogene; 2004 Mar; 23(9):1737-44. PubMed ID: 15001986
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Relationships between G1 arrest and stability of the p53 and p21Cip1/Waf1 proteins following gamma-irradiation of human lymphoma cells.
    Bae I; Fan S; Bhatia K; Kohn KW; Fornace AJ; O'Connor PM
    Cancer Res; 1995 Jun; 55(11):2387-93. PubMed ID: 7757991
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells.
    Di Gennaro E; Barbarino M; Bruzzese F; De Lorenzo S; Caraglia M; Abbruzzese A; Avallone A; Comella P; Caponigro F; Pepe S; Budillon A
    J Cell Physiol; 2003 Apr; 195(1):139-50. PubMed ID: 12599217
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TGF-beta mediated G1 arrest in a human melanoma cell line lacking p15INK4B: evidence for cooperation between p21Cip1/WAF1 and p27Kip1.
    Flørenes VA; Bhattacharya N; Bani MR; Ben-David Y; Kerbel RS; Slingerland JM
    Oncogene; 1996 Dec; 13(11):2447-57. PubMed ID: 8957087
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular mechanisms underlying interferon-alpha-induced G0/G1 arrest: CKI-mediated regulation of G1 Cdk-complexes and activation of pocket proteins.
    Sangfelt O; Erickson S; Castro J; Heiden T; Gustafsson A; Einhorn S; Grandér D
    Oncogene; 1999 May; 18(18):2798-810. PubMed ID: 10362250
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.