BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

289 related articles for article (PubMed ID: 15345369)

  • 1. Valproic acid teratogenicity: a toxicogenomics approach.
    Kultima K; Nyström AM; Scholz B; Gustafson AL; Dencker L; Stigson M
    Environ Health Perspect; 2004 Aug; 112(12):1225-35. PubMed ID: 15345369
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Short-time gene expression response to valproic acid and valproic acid analogs in mouse embryonic stem cells.
    Jergil M; Forsberg M; Salter H; Stockling K; Gustafson AL; Dencker L; Stigson M
    Toxicol Sci; 2011 Jun; 121(2):328-42. PubMed ID: 21427059
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Valproic acid-induced deregulation in vitro of genes associated in vivo with neural tube defects.
    Jergil M; Kultima K; Gustafson AL; Dencker L; Stigson M
    Toxicol Sci; 2009 Mar; 108(1):132-48. PubMed ID: 19136453
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New molecular bioassays for the estimation of the teratogenic potency of valproic acid derivatives in vitro: activation of the peroxisomal proliferator-activated receptor (PPARdelta).
    Lampen A; Siehler S; Ellerbeck U; Göttlicher M; Nau H
    Toxicol Appl Pharmacol; 1999 Nov; 160(3):238-49. PubMed ID: 10544058
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ribonucleotide reductase subunit R1: a gene conferring sensitivity to valproic acid-induced neural tube defects in mice.
    Craig JC; Bennett GD; Miranda RC; Mackler SA; Finnell RH
    Teratology; 2000 Apr; 61(4):305-13. PubMed ID: 10716750
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of early-responsive genes correlated to valproic acid-induced neural tube defects in mice.
    Okada A; Kushima K; Aoki Y; Bialer M; Fujiwara M
    Birth Defects Res A Clin Mol Teratol; 2005 Apr; 73(4):229-38. PubMed ID: 15799026
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Polycomb homologs are involved in teratogenicity of valproic acid in mice.
    Okada A; Aoki Y; Kushima K; Kurihara H; Bialer M; Fujiwara M
    Birth Defects Res A Clin Mol Teratol; 2004 Nov; 70(11):870-9. PubMed ID: 15523661
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Teratogenicity of valproate conjugates with anticonvulsant activity in mice.
    Spiegelstein O; Chatterjie N; Alexander G; Finnell RH
    Epilepsy Res; 2003 Dec; 57(2-3):145-52. PubMed ID: 15013055
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Association of valproate-induced teratogenesis with histone deacetylase inhibition in vivo.
    Gurvich N; Berman MG; Wittner BS; Gentleman RC; Klein PS; Green JB
    FASEB J; 2005 Jul; 19(9):1166-8. PubMed ID: 15901671
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Folic acid and pantothenic acid protection against valproic acid-induced neural tube defects in CD-1 mice.
    Dawson JE; Raymond AM; Winn LM
    Toxicol Appl Pharmacol; 2006 Mar; 211(2):124-32. PubMed ID: 16112698
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Valproic acid increases formation of reactive oxygen species and induces apoptosis in postimplantation embryos: a role for oxidative stress in valproic acid-induced neural tube defects.
    Tung EW; Winn LM
    Mol Pharmacol; 2011 Dec; 80(6):979-87. PubMed ID: 21868484
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Early transcriptional responses in mouse embryos as a basis for selection of molecular markers predictive of valproic acid teratogenicity.
    Kultima K; Jergil M; Salter H; Gustafson AL; Dencker L; Stigson M
    Reprod Toxicol; 2010 Nov; 30(3):457-68. PubMed ID: 20546886
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolite profiling of whole murine embryos reveals metabolic perturbations associated with maternal valproate-induced neural tube closure defects.
    Akimova D; Wlodarczyk BJ; Lin Y; Ross ME; Finnell RH; Chen Q; Gross SS
    Birth Defects Res; 2017 Jan; 109(2):106-119. PubMed ID: 27860192
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Prediction of embryotoxic effects of valproic acid-derivatives with molecular in vitro methods.
    Lampen A; Göttlicher M; Nau H
    ALTEX; 2001; 18(2):123-6. PubMed ID: 11378687
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Multiple point action mechanism of valproic acid-teratogenicity alleviated by folic acid, vitamin C, and N-acetylcysteine in chicken embryo model.
    Hsieh CL; Wang HE; Tsai WJ; Peng CC; Peng RY
    Toxicology; 2012 Jan; 291(1-3):32-42. PubMed ID: 22051200
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Valproic acid-induced alterations in growth and neurotrophic factor gene expression in murine embryos [corrected].
    Bennett GD; Wlodarczyk B; Calvin JA; Craig JC; Finnell RH
    Reprod Toxicol; 2000; 14(1):1-11. PubMed ID: 10689198
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Teratogenic effects mediated by inhibition of histone deacetylases: evidence from quantitative structure activity relationships of 20 valproic acid derivatives.
    Eikel D; Lampen A; Nau H
    Chem Res Toxicol; 2006 Feb; 19(2):272-8. PubMed ID: 16485903
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel targets for valproic acid: up-regulation of melatonin receptors and neurotrophic factors in C6 glioma cells.
    Castro LM; Gallant M; Niles LP
    J Neurochem; 2005 Dec; 95(5):1227-36. PubMed ID: 16313512
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Myo-inositol enhances teratogenicity of valproic acid in the mouse.
    Massa V; Wlodarczyk B; Giavini E; Finnell RH
    Birth Defects Res A Clin Mol Teratol; 2006 Mar; 76(3):200-4. PubMed ID: 16511884
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Valproic acid-induced neural tube defects in mouse and human: aspects of chirality, alternative drug development, pharmacokinetics and possible mechanisms.
    Nau H; Hauck RS; Ehlers K
    Pharmacol Toxicol; 1991 Nov; 69(5):310-21. PubMed ID: 1803343
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.