BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

364 related articles for article (PubMed ID: 15345587)

  • 1. Expression of hepcidin is down-regulated in TfR2 mutant mice manifesting a phenotype of hereditary hemochromatosis.
    Kawabata H; Fleming RE; Gui D; Moon SY; Saitoh T; O'Kelly J; Umehara Y; Wano Y; Said JW; Koeffler HP
    Blood; 2005 Jan; 105(1):376-81. PubMed ID: 15345587
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Iron uptake from plasma transferrin by a transferrin receptor 2 mutant mouse model of haemochromatosis.
    Chua AC; Delima RD; Morgan EH; Herbison CE; Tirnitz-Parker JE; Graham RM; Fleming RE; Britton RS; Bacon BR; Olynyk JK; Trinder D
    J Hepatol; 2010 Mar; 52(3):425-31. PubMed ID: 20133002
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Iron absorption and hepatic iron uptake are increased in a transferrin receptor 2 (Y245X) mutant mouse model of hemochromatosis type 3.
    Drake SF; Morgan EH; Herbison CE; Delima R; Graham RM; Chua AC; Leedman PJ; Fleming RE; Bacon BR; Olynyk JK; Trinder D
    Am J Physiol Gastrointest Liver Physiol; 2007 Jan; 292(1):G323-8. PubMed ID: 16935854
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis.
    Fleming RE; Ahmann JR; Migas MC; Waheed A; Koeffler HP; Kawabata H; Britton RS; Bacon BR; Sly WS
    Proc Natl Acad Sci U S A; 2002 Aug; 99(16):10653-8. PubMed ID: 12134060
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Global loss of Tfr2 with concomitant induced iron deficiency greatly ameliorates the phenotype of a murine thalassemia intermedia model.
    Schmidt PJ; Fitzgerald K; Butler JS; Fleming MD
    Am J Hematol; 2021 Feb; 96(2):251-257. PubMed ID: 33180328
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Iron regulation of hepcidin despite attenuated Smad1,5,8 signaling in mice without transferrin receptor 2 or Hfe.
    Corradini E; Rozier M; Meynard D; Odhiambo A; Lin HY; Feng Q; Migas MC; Britton RS; Babitt JL; Fleming RE
    Gastroenterology; 2011 Nov; 141(5):1907-14. PubMed ID: 21745449
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice.
    Delima RD; Chua AC; Tirnitz-Parker JE; Gan EK; Croft KD; Graham RM; Olynyk JK; Trinder D
    Hepatology; 2012 Aug; 56(2):585-93. PubMed ID: 22383097
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis.
    Fleming RE; Migas MC; Holden CC; Waheed A; Britton RS; Tomatsu S; Bacon BR; Sly WS
    Proc Natl Acad Sci U S A; 2000 Feb; 97(5):2214-9. PubMed ID: 10681454
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice.
    Ramos E; Kautz L; Rodriguez R; Hansen M; Gabayan V; Ginzburg Y; Roth MP; Nemeth E; Ganz T
    Hepatology; 2011 Apr; 53(4):1333-41. PubMed ID: 21480335
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Regulatory networks for the control of body iron homeostasis and their dysregulation in HFE mediated hemochromatosis.
    Ludwiczek S; Theurl I; Bahram S; Schümann K; Weiss G
    J Cell Physiol; 2005 Aug; 204(2):489-99. PubMed ID: 15744772
    [TBL] [Abstract][Full Text] [Related]  

  • 11. First phenotypic description of transferrin receptor 2 knockout mouse, and the role of hepcidin.
    Wallace DF; Summerville L; Lusby PE; Subramaniam VN
    Gut; 2005 Jul; 54(7):980-6. PubMed ID: 15951546
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Blunted hepcidin response to inflammation in the absence of Hfe and transferrin receptor 2.
    Wallace DF; McDonald CJ; Ostini L; Subramaniam VN
    Blood; 2011 Mar; 117(10):2960-6. PubMed ID: 21245482
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6.
    Truksa J; Peng H; Lee P; Beutler E
    Proc Natl Acad Sci U S A; 2006 Jul; 103(27):10289-10293. PubMed ID: 16801541
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interaction of the hereditary hemochromatosis protein HFE with transferrin receptor 2 is required for transferrin-induced hepcidin expression.
    Gao J; Chen J; Kramer M; Tsukamoto H; Zhang AS; Enns CA
    Cell Metab; 2009 Mar; 9(3):217-27. PubMed ID: 19254567
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-alpha and Tfr2-beta isoforms in different tissues.
    Roetto A; Di Cunto F; Pellegrino RM; Hirsch E; Azzolino O; Bondi A; Defilippi I; Carturan S; Miniscalco B; Riondato F; Cilloni D; Silengo L; Altruda F; Camaschella C; Saglio G
    Blood; 2010 Apr; 115(16):3382-9. PubMed ID: 20179178
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transgenic HFE-dependent induction of hepcidin in mice does not require transferrin receptor-2.
    Schmidt PJ; Fleming MD
    Am J Hematol; 2012 Jun; 87(6):588-95. PubMed ID: 22460705
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Hepatic iron deposition does not predict extrahepatic iron loading in mouse models of hereditary hemochromatosis.
    Subramaniam VN; McDonald CJ; Ostini L; Lusby PE; Wockner LF; Ramm GA; Wallace DF
    Am J Pathol; 2012 Oct; 181(4):1173-9. PubMed ID: 22858058
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A novel rat model of hereditary hemochromatosis due to a mutation in transferrin receptor 2.
    Bartnikas TB; Wildt SJ; Wineinger AE; Schmitz-Abe K; Markianos K; Cooper DM; Fleming MD
    Comp Med; 2013 Apr; 63(2):143-55. PubMed ID: 23582421
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hereditary hemochromatosis and transferrin receptor 2.
    Chen J; Enns CA
    Biochim Biophys Acta; 2012 Mar; 1820(3):256-63. PubMed ID: 21864651
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Smad6 and Smad7 are co-regulated with hepcidin in mouse models of iron overload.
    Vujić Spasić M; Sparla R; Mleczko-Sanecka K; Migas MC; Breitkopf-Heinlein K; Dooley S; Vaulont S; Fleming RE; Muckenthaler MU
    Biochim Biophys Acta; 2013 Jan; 1832(1):76-84. PubMed ID: 22960056
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.