These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

310 related articles for article (PubMed ID: 15345707)

  • 1. Mutation in saposin D domain of sphingolipid activator protein gene causes urinary system defects and cerebellar Purkinje cell degeneration with accumulation of hydroxy fatty acid-containing ceramide in mouse.
    Matsuda J; Kido M; Tadano-Aritomi K; Ishizuka I; Tominaga K; Toida K; Takeda E; Suzuki K; Kuroda Y
    Hum Mol Genet; 2004 Nov; 13(21):2709-23. PubMed ID: 15345707
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Combined saposin C and D deficiencies in mice lead to a neuronopathic phenotype, glucosylceramide and alpha-hydroxy ceramide accumulation, and altered prosaposin trafficking.
    Sun Y; Witte DP; Zamzow M; Ran H; Quinn B; Matsuda J; Grabowski GA
    Hum Mol Genet; 2007 Apr; 16(8):957-71. PubMed ID: 17353235
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The function of sphingolipids in the nervous system: lessons learnt from mouse models of specific sphingolipid activator protein deficiencies.
    Matsuda J; Yoneshige A; Suzuki K
    J Neurochem; 2007 Nov; 103 Suppl 1():32-8. PubMed ID: 17986137
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A mutation in the saposin C domain of the sphingolipid activator protein (Prosaposin) gene causes neurodegenerative disease in mice.
    Yoneshige A; Suzuki K; Suzuki K; Matsuda J
    J Neurosci Res; 2010 Aug; 88(10):2118-34. PubMed ID: 20175216
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The exon 8-containing prosaposin gene splice variant is dispensable for mouse development, lysosomal function, and secretion.
    Cohen T; Auerbach W; Ravid L; Bodennec J; Fein A; Futerman AH; Joyner AL; Horowitz M
    Mol Cell Biol; 2005 Mar; 25(6):2431-40. PubMed ID: 15743835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structural analysis of the mouse prosaposin (SGP-1) gene reveals the presence of an exon that is alternatively spliced in transcribed mRNAs.
    Zhao Q; Hay N; Morales CR
    Mol Reprod Dev; 1997 Sep; 48(1):1-8. PubMed ID: 9266755
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional characterization of the postulated intramolecular sphingolipid activator protein domain of human acid sphingomyelinase.
    Kölzer M; Ferlinz K; Bartelsen O; Hoops SL; Lang F; Sandhoff K
    Biol Chem; 2004 Dec; 385(12):1193-5. PubMed ID: 15653433
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Saposin C: neuronal effect and CNS delivery by liposomes.
    Chu Z; Sun Y; Kuan CY; Grabowski GA; Qi X
    Ann N Y Acad Sci; 2005 Aug; 1053():237-46. PubMed ID: 16179529
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Lysosomal proteolysis of prosaposin, the precursor of saposins (sphingolipid activator proteins): its mechanism and inhibition by ganglioside.
    Hiraiwa M; Martin BM; Kishimoto Y; Conner GE; Tsuji S; O'Brien JS
    Arch Biochem Biophys; 1997 May; 341(1):17-24. PubMed ID: 9143348
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An Asn > Lys substitution in saposin B involving a conserved amino acidic residue and leading to the loss of the single N-glycosylation site in a patient with metachromatic leukodystrophy and normal arylsulphatase A activity.
    Regis S; Filocamo M; Corsolini F; Caroli F; Keulemans JL; van Diggelen OP; Gatti R
    Eur J Hum Genet; 1999; 7(2):125-30. PubMed ID: 10196694
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structures of the human ceramide activator protein saposin D.
    Popovic K; Privé GG
    Acta Crystallogr D Biol Crystallogr; 2008 May; 64(Pt 5):589-94. PubMed ID: 18453694
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A mutation in the saposin A domain of the sphingolipid activator protein (prosaposin) gene results in a late-onset, chronic form of globoid cell leukodystrophy in the mouse.
    Matsuda J; Vanier MT; Saito Y; Tohyama J; Suzuki K; Suzuki K
    Hum Mol Genet; 2001 May; 10(11):1191-9. PubMed ID: 11371512
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Conservation of expression and alternative splicing in the prosaposin gene.
    Cohen T; Ravid L; Altman N; Madar-Shapiro L; Fein A; Weil M; Horowitz M
    Brain Res Mol Brain Res; 2004 Oct; 129(1-2):8-19. PubMed ID: 15469878
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The toppler mouse: a novel mutant exhibiting loss of Purkinje cells.
    Duchala CS; Shick HE; Garcia J; Deweese DM; Sun X; Stewart VJ; Macklin WB
    J Comp Neurol; 2004 Aug; 476(2):113-29. PubMed ID: 15248193
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Stimulation of acid ceramidase activity by saposin D.
    Azuma N; O'Brien JS; Moser HW; Kishimoto Y
    Arch Biochem Biophys; 1994 Jun; 311(2):354-7. PubMed ID: 8203897
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Disorders of sphingolipid activator proteins].
    Suzuki Y
    Nihon Rinsho; 1995 Dec; 53(12):3025-7. PubMed ID: 8577053
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A missense mutation in the WD40 domain of murine Lyst is linked to severe progressive Purkinje cell degeneration.
    Rudelius M; Osanger A; Kohlmann S; Augustin M; Piontek G; Heinzmann U; Jennen G; Russ A; Matiasek K; Stumm G; Schlegel J
    Acta Neuropathol; 2006 Sep; 112(3):267-76. PubMed ID: 16791600
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Role of saposin C and D in auditory and vestibular function.
    Lustig LR; Alemi S; Sun Y; Grabowski G; Akil O
    Laryngoscope; 2016 Feb; 126(2):452-9. PubMed ID: 26198053
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Distribution of prosaposin in the rat nervous system.
    Hosoda Y; Miyawaki K; Saito S; Chen J; Bing X; Terashita T; Kobayashi N; Araki N; Shimokawa T; Hamada F; Sano A; Tanabe H; Matsuda S
    Cell Tissue Res; 2007 Nov; 330(2):197-207. PubMed ID: 17763872
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Sphingolipid activator protein D (sap-D) stimulates the lysosomal degradation of ceramide in vivo.
    Klein A; Henseler M; Klein C; Suzuki K; Harzer K; Sandhoff K
    Biochem Biophys Res Commun; 1994 May; 200(3):1440-8. PubMed ID: 8185598
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.