These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

198 related articles for article (PubMed ID: 15345711)

  • 1. Reduced beta-amyloid production and increased inflammatory responses in presenilin conditional knock-out mice.
    Beglopoulos V; Sun X; Saura CA; Lemere CA; Kim RD; Shen J
    J Biol Chem; 2004 Nov; 279(45):46907-14. PubMed ID: 15345711
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Environment enrichment rescues the neurodegenerative phenotypes in presenilins-deficient mice.
    Dong S; Li C; Wu P; Tsien JZ; Hu Y
    Eur J Neurosci; 2007 Jul; 26(1):101-12. PubMed ID: 17614943
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Enhanced oxidative stress is an early event during development of Alzheimer-like pathologies in presenilin conditional knock-out mice.
    Gu F; Zhu M; Shi J; Hu Y; Zhao Z
    Neurosci Lett; 2008 Jul; 440(1):44-8. PubMed ID: 18539391
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Increased inflammatory response both in brain and in periphery in presenilin 1 and presenilin 2 conditional double knock-out mice.
    Jiang X; Zhang D; Shi J; Chen Y; Zhang P; Mei B
    J Alzheimers Dis; 2009; 18(3):515-23. PubMed ID: 19584449
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Cell-autonomous role of Presenilin in age-dependent survival of cortical interneurons.
    Kang J; Shen J
    Mol Neurodegener; 2020 Dec; 15(1):72. PubMed ID: 33302995
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loss of presenilin function causes impairments of memory and synaptic plasticity followed by age-dependent neurodegeneration.
    Saura CA; Choi SY; Beglopoulos V; Malkani S; Zhang D; Shankaranarayana Rao BS; Chattarji S; Kelleher RJ; Kandel ER; Duff K; Kirkwood A; Shen J
    Neuron; 2004 Apr; 42(1):23-36. PubMed ID: 15066262
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hippocampal spatial memory impairments caused by the familial Alzheimer's disease-linked presenilin 1 M146V mutation.
    Sun X; Beglopoulos V; Mattson MP; Shen J
    Neurodegener Dis; 2005; 2(1):6-15. PubMed ID: 16908998
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Promotion of β-amyloid production by C-reactive protein and its implications in the early pathogenesis of Alzheimer's disease.
    Bi BT; Lin HB; Cheng YF; Zhou H; Lin T; Zhang MZ; Li TJ; Xu JP
    Neurochem Int; 2012 Feb; 60(3):257-66. PubMed ID: 22202667
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Presenilins regulate synaptic plasticity and mitochondrial calcium homeostasis in the hippocampal mossy fiber pathway.
    Lee SH; Lutz D; Mossalam M; Bolshakov VY; Frotscher M; Shen J
    Mol Neurodegener; 2017 Jun; 12(1):48. PubMed ID: 28619096
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [Modified Kaixin San improves memory and synaptic damage of mice with Alzheimer's disease by modulating αCaMKⅡ-PSD95 protein binding through inhibition of neuroinflammation:a study of mechanism].
    Lu ZY; Zhao CY; Yang G; Tong YT; Ba ZT; Reaila A; Yang JM; Xu Y
    Zhongguo Zhong Yao Za Zhi; 2022 Nov; 47(22):6217-6226. PubMed ID: 36471948
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.
    Steiner H; Capell A; Leimer U; Haass C
    Eur Arch Psychiatry Clin Neurosci; 1999; 249(6):266-70. PubMed ID: 10653281
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Increased oxidative stress and astrogliosis responses in conditional double-knockout mice of Alzheimer-like presenilin-1 and presenilin-2.
    Zhu M; Gu F; Shi J; Hu J; Hu Y; Zhao Z
    Free Radic Biol Med; 2008 Nov; 45(10):1493-9. PubMed ID: 18822370
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Trans-cinnamaldehyde improves neuroinflammation-mediated NMDA receptor dysfunction and memory deficits through blocking NF-κB pathway in presenilin1/2 conditional double knockout mice.
    Zhao Y; Deng H; Li K; Wang L; Wu Y; Dong X; Wang X; Chen Y; Xu Y
    Brain Behav Immun; 2019 Nov; 82():45-62. PubMed ID: 31376499
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Characterization of age-dependent and progressive cortical neuronal degeneration in presenilin conditional mutant mice.
    Wines-Samuelson M; Schulte EC; Smith MJ; Aoki C; Liu X; Kelleher RJ; Shen J
    PLoS One; 2010 Apr; 5(4):e10195. PubMed ID: 20419112
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Presenilins regulate synaptic plasticity in the perforant pathways of the hippocampus.
    Lee SH; Bolshakov VY; Shen J
    Mol Brain; 2023 Jan; 16(1):17. PubMed ID: 36710361
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ibuprofen partially attenuates neurodegenerative symptoms in presenilin conditional double-knockout mice.
    Dong Z; Yan L; Huang G; Zhang L; Mei B; Meng B
    Neuroscience; 2014 Jun; 270():58-68. PubMed ID: 24699228
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Histone Deacetylase Inhibitor Alleviates the Neurodegenerative Phenotypes and Histone Dysregulation in Presenilins-Deficient Mice.
    Cao T; Zhou X; Zheng X; Cui Y; Tsien JZ; Li C; Wang H
    Front Aging Neurosci; 2018; 10():137. PubMed ID: 29867447
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inactivation of Presenilin in inhibitory neurons results in decreased GABAergic responses and enhanced synaptic plasticity.
    Lee SH; Bolshakov VY; Shen J
    Mol Brain; 2021 May; 14(1):85. PubMed ID: 34034776
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A pathogenic presenilin-1 deletion causes abberrant Abeta 42 production in the absence of congophilic amyloid plaques.
    Steiner H; Revesz T; Neumann M; Romig H; Grim MG; Pesold B; Kretzschmar HA; Hardy J; Holton JL; Baumeister R; Houlden H; Haass C
    J Biol Chem; 2001 Mar; 276(10):7233-9. PubMed ID: 11084029
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Partial loss of presenilin impairs age-dependent neuronal survival in the cerebral cortex.
    Watanabe H; Iqbal M; Zheng J; Wines-Samuelson M; Shen J
    J Neurosci; 2014 Nov; 34(48):15912-22. PubMed ID: 25429133
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.