238 related articles for article (PubMed ID: 15353372)
1. Development of new anti-cancer peptides from conformational energy analysis of the oncogenic ras-p21 protein and its complexes with target proteins.
Pincus MR
Front Biosci; 2004 Sep; 9():3486-509. PubMed ID: 15353372
[TBL] [Abstract][Full Text] [Related]
2. Specificity of inhibition of ras-p21 signal transduction by peptides from GTPase activating protein (GAP) and the son-of sevenless (SOS) ras-specific guanine nucleotide exchange protein.
Chie L; Chung D; Pincus MR
Protein J; 2005 May; 24(4):253-8. PubMed ID: 16283548
[TBL] [Abstract][Full Text] [Related]
3. Anti-cancer peptides from ras-p21 and p53 proteins.
Pincus MR; Fenelus M; Sarafraz-Yazdi E; Adler V; Bowne W; Michl J
Curr Pharm Des; 2011; 17(25):2677-98. PubMed ID: 21728981
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of ras-induced oocyte maturation by peptides from ras-p21 and GTPase activating protein (GAP) identified as being effector domains from molecular dynamics calculations.
Friedman FK; Chie L; Chung D; Robinson R; Brandt-Rauf P; Yamaizumi Z; Pincus MR
J Protein Chem; 2002 Jul; 21(5):361-6. PubMed ID: 12206510
[TBL] [Abstract][Full Text] [Related]
5. Comparison of the computed three-dimensional structures of oncogenic forms (bound to GDP) of the ras-gene-encoded p21 protein with the structure of the normal (non-transforming) wild-type protein.
Monaco R; Chen JM; Chung D; Brandt-Rauf P; Pincus MR
J Protein Chem; 1995 Aug; 14(6):457-66. PubMed ID: 8593186
[TBL] [Abstract][Full Text] [Related]
6. Comparison of the average structures, from molecular dynamics, of complexes of GTPase activating protein (GAP) with oncogenic and wild-type ras-p21: identification of potential effector domains.
Chen JM; Friedman FK; Brandt-Rauf PW; Pincus MR; Chie L
J Protein Chem; 2002 Jul; 21(5):349-59. PubMed ID: 12206509
[TBL] [Abstract][Full Text] [Related]
7. Peptides designed from molecular modeling studies of the ras-p21 protein induce phenotypic reversion of a pancreatic carcinoma cell line but have no effect on normal pancreatic acinar cell growth.
Kanovsky M; Michl J; Botzolaki G; Morin J; Kovac C; Chung DL; Chie L; Friedman FK; Pincus MR
Cancer Chemother Pharmacol; 2003 Sep; 52(3):202-8. PubMed ID: 12783204
[TBL] [Abstract][Full Text] [Related]
8. Identification, using molecular dynamics, of an effector domain of the ras-binding domain of the raf-p74 protein that is uniquely involved in oncogenic ras-p21 signaling.
Chen JM; Rijhwani K; Friedman FK; Hyde MJ; Pincus MR
J Protein Chem; 2000 Oct; 19(7):545-51. PubMed ID: 11233167
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of oncogenic and activated wild-type ras-p21 protein-induced oocyte maturation by peptides from the guanine-nucleotide exchange protein, SOS, identified from molecular dynamics calculations. Selective inhibition of oncogenic ras-p21.
Chie L; Chen JM; Friedman FK; Chung DL; Amar S; Michl J; Yamaizumi Z; Brandt-Rauf PW; Pincus MR
J Protein Chem; 1999 Nov; 18(8):875-9. PubMed ID: 10839624
[TBL] [Abstract][Full Text] [Related]
10. Loop domain peptides from the SOS ras-guanine nucleotide exchange protein, identified from molecular dynamics calculations, strongly inhibit ras signaling.
Chie L; Friedman FK; Duncan T; Chen JM; Chung D; Pincus M
Protein J; 2004 Apr; 23(3):229-34. PubMed ID: 15200054
[TBL] [Abstract][Full Text] [Related]
11. Two peptides derived from ras-p21 induce either phenotypic reversion or tumor cell necrosis of ras-transformed human cancer cells.
Adler V; Bowne W; Kamran I; Michl J; Friedman FK; Chin E; Zenilman M; Pincus MR
Cancer Chemother Pharmacol; 2008 Aug; 62(3):491-8. PubMed ID: 18066549
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of oncogenic and activated wild-type ras-p21 protein-induced oocyte maturation by peptides from the ras-binding domain of the raf-p74 protein, identified from molecular dynamics calculations.
Chung D; Amar S; Glozman A; Chen JM; Friedman FK; Robinson R; Monaco R; Brandt-Rauf P; Yamaizumi Z; Pincus MR
J Protein Chem; 1997 Aug; 16(6):631-5. PubMed ID: 9263125
[TBL] [Abstract][Full Text] [Related]
13. Peptides That Block RAS-p21 Protein-Induced Cell Transformation.
Pincus MR; Lin B; Patel P; Gabutan E; Zohar N; Bowne WB
Biomedicines; 2023 Feb; 11(2):. PubMed ID: 36831007
[TBL] [Abstract][Full Text] [Related]
14. A peptide from the GAP-binding domain of the ras-p21 protein and azatyrosine block ras-induced maturation of Xenopus oocytes.
Chung DL; Brandt-Rauf P; Murphy RB; Nishimura S; Yamaizumi Z; Weinstein IB; Pincus MR
Anticancer Res; 1991; 11(4):1373-8. PubMed ID: 1746893
[TBL] [Abstract][Full Text] [Related]
15. Plasmid expression of a peptide that selectively blocks oncogenic ras-p21-induced oocyte maturation.
Kovac C; Clie L; Morin J; Friedman FK; Robinson R; Chung DL; Kanovsky M; Flom J; Brandt-Rauf PW; Yamaizumi Z; Michl J; Pincus MR
Cancer Chemother Pharmacol; 2001 Jul; 48(1):9-14. PubMed ID: 11488531
[TBL] [Abstract][Full Text] [Related]
16. The dual-specificity kinases, TOPK and DYRK1A, are critical for oocyte maturation induced by wild-type--but not by oncogenic--ras-p21 protein.
Qu Y; Adler V; Izotova L; Pestka S; Bowne W; Michl J; Boutjdir M; Friedman FK; Pincus MR
Front Biosci; 2007 Sep; 12():5089-97. PubMed ID: 17569632
[TBL] [Abstract][Full Text] [Related]
17. Two dual specificity kinases are preferentially induced by wild-type rather than by oncogenic RAS-P21 in Xenopus oocytes.
Qu Y; Adler V; Chu T; Platica O; Michl J; Pestka S; Izotova L; Boutjdir M; Pincus MR
Front Biosci; 2006 Sep; 11():2420-7. PubMed ID: 16720323
[TBL] [Abstract][Full Text] [Related]
18. Comparison of the low energy conformations of an oncogenic and a non-oncogenic p21 protein, neither of which binds GTP or GDP.
Liwo A; Gibson KD; Scheraga HA; Brandt-Rauf PW; Monaco R; Pincus MR
J Protein Chem; 1994 Feb; 13(2):237-51. PubMed ID: 8060496
[TBL] [Abstract][Full Text] [Related]
19. Induction of oocyte maturation by jun-N-terminal kinase (JNK) on the oncogenic ras-p21 pathway is dependent on the raf-MEK signal transduction pathway.
Chie L; Amar S; Kung HF; Lin MC; Chen H; Chung DL; Adler V; Ronai Z; Friedman FK; Robinson RC; Kovac C; Brandt-Rauf PW; Yamaizumi Z; Michl J; Pincus MR
Cancer Chemother Pharmacol; 2000; 45(6):441-9. PubMed ID: 10854130
[TBL] [Abstract][Full Text] [Related]
20. Comparison of molecular dynamics averaged structures for complexes of normal and oncogenic ras-p21 with SOS nucleotide exchange protein, containing computed conformations for three crystallographically undefined domains, suggests a potential role of these domains in ras signaling.
Duncan T; Chen JM; Friedman FK; Hyde M; Chie L; Pincus MR
Protein J; 2004 Apr; 23(3):217-28. PubMed ID: 15200053
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
