These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

112 related articles for article (PubMed ID: 15357987)

  • 41. An inhibitory metabolite leads to dose- and time-dependent pharmacokinetics of (R)-N-{1-[3-(4-ethoxy-phenyl)-4-oxo-3,4-dihydro-pyrido[2,3-d]pyrimidin-2-yl]-ethyl}-N-pyridin-3-yl-methyl-2-(4-trifluoromethoxy-phenyl)-acetamide (AMG 487) in human subjects after multiple dosing.
    Tonn GR; Wong SG; Wong SC; Johnson MG; Ma J; Cho R; Floren LC; Kersey K; Berry K; Marcus AP; Wang X; Van Lengerich B; Medina JC; Pearson PG; Wong BK
    Drug Metab Dispos; 2009 Mar; 37(3):502-13. PubMed ID: 19088267
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Identification of novel short chain 4-substituted indoles as potent alphavbeta3 antagonist using structure-based drug design.
    Raboisson P; Desjarlais RL; Reed R; Lattanze J; Chaikin M; Manthey CL; Tomczuk BE; Marugán JJ
    Eur J Med Chem; 2007 Mar; 42(3):334-43. PubMed ID: 17184884
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Evolution of novel tricyclic CRTh2 receptor antagonists from a (E)-2-cyano-3-(1H-indol-3-yl)acrylamide scaffold.
    Valdenaire A; Pothier J; Renneberg D; Riederer MA; Peter O; Leroy X; Gnerre C; Fretz H
    Bioorg Med Chem Lett; 2013 Feb; 23(4):944-8. PubMed ID: 23324405
    [TBL] [Abstract][Full Text] [Related]  

  • 44. QSAR, diagnostic statistics, and molecular modelling of antiallergic acrylamide derivatives.
    Mager PP
    Drug Des Discov; 1992; 9(2):107-18. PubMed ID: 1296796
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Partial agonism, neutral antagonism, and inverse agonism at the human wild-type and constitutively active cholecystokinin-2 receptors.
    Foucaud M; Tikhonova IG; Langer I; Escrieut C; Dufresne M; Seva C; Maigret B; Fourmy D
    Mol Pharmacol; 2006 Mar; 69(3):680-90. PubMed ID: 16293711
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Convenient synthesis and antimicrobial activity of new 3-substituted 5-(benzofuran-2-yl)-pyrazole derivatives.
    Abdel-Wahab BF; Abdel-Aziz HA; Ahmed EM
    Arch Pharm (Weinheim); 2008 Nov; 341(11):734-9. PubMed ID: 18816590
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Synthesis and pharmacological evaluation of aminopyrimidine series of 5-HT1A partial agonists.
    Dounay AB; Barta NS; Bikker JA; Borosky SA; Campbell BM; Crawford T; Denny L; Evans LM; Gray DL; Lee P; Lenoir EA; Xu W
    Bioorg Med Chem Lett; 2009 Feb; 19(4):1159-63. PubMed ID: 19147349
    [TBL] [Abstract][Full Text] [Related]  

  • 48. GABAA receptor pharmacology of fluorinated derivatives of the novel sedative-hypnotic pyrazolopyrimidine indiplon.
    Wegner F; Deuther-Conrad W; Scheunemann M; Brust P; Fischer S; Hiller A; Diekers M; Strecker K; Wohlfarth K; Allgaier C; Steinbach J; Hoepping A
    Eur J Pharmacol; 2008 Feb; 580(1-2):1-11. PubMed ID: 18035350
    [TBL] [Abstract][Full Text] [Related]  

  • 49. (R)-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)-urea (ABT-102) blocks polymodal activation of transient receptor potential vanilloid 1 receptors in vitro and heat-evoked firing of spinal dorsal horn neurons in vivo.
    Surowy CS; Neelands TR; Bianchi BR; McGaraughty S; El Kouhen R; Han P; Chu KL; McDonald HA; Vos M; Niforatos W; Bayburt EK; Gomtsyan A; Lee CH; Honore P; Sullivan JP; Jarvis MF; Faltynek CR
    J Pharmacol Exp Ther; 2008 Sep; 326(3):879-88. PubMed ID: 18515644
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents.
    Küçükgüzel I; Tatar E; Küçükgüzel SG; Rollas S; De Clercq E
    Eur J Med Chem; 2008 Feb; 43(2):381-92. PubMed ID: 17583388
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Expression of a calmodulin-binding KCNQ2 potassium channel fragment modulates neuronal M-current and membrane excitability.
    Shahidullah M; Santarelli LC; Wen H; Levitan IB
    Proc Natl Acad Sci U S A; 2005 Nov; 102(45):16454-9. PubMed ID: 16263935
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Synthesis of 2-(4-substitutedmethylpiperazin-1-yl)-N-(3,4-dihydro-3-oxo-2H-benzo[b][1,4]oxazin-7-yl)acetamides and their positive inotropic evaluation.
    Liu XK; Cui X; Hong L; Sun LP; Quan ZS; Piao HR
    Eur J Med Chem; 2009 Jul; 44(7):3027-31. PubMed ID: 18824278
    [TBL] [Abstract][Full Text] [Related]  

  • 53. N, N' (4,5-dihydro-1h-imidazol-2-yl)3-aza-1,10-decane-diamine and N, N'(4,5-dihydro-1H-imidazol-2-yl)3-aza-1, 10-dodecane-diamine antagonize cell proliferation as selective ligands towards topoisomerase II.
    Filosa R; Buonerba M; Loddo R; Busonera B; La Colla P; Saturnino C
    J Pharm Pharmacol; 2006 Oct; 58(10):1415-20. PubMed ID: 17034667
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Discovery of 2-[5-(4-chloro-phenyl)-1-(2,4-dichloro-phenyl)-4-ethyl-1H-pyrazol-3-yl]-1,5,5-trimethyl-1,5-dihydro-imidazol-4-thione (BPR-890) via an active metabolite. A novel, potent and selective cannabinoid-1 receptor inverse agonist with high antiobesity efficacy in DIO mice.
    Wu CH; Hung MS; Song JS; Yeh TK; Chou MC; Chu CM; Jan JJ; Hsieh MT; Tseng SL; Chang CP; Hsieh WP; Lin Y; Yeh YN; Chung WL; Kuo CW; Lin CY; Shy HS; Chao YS; Shia KS
    J Med Chem; 2009 Jul; 52(14):4496-510. PubMed ID: 19530697
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Synthesis and antinociceptive activity of some substituted-{5-[2-(1,2,3,4-tetrahydrocarbazol-9-yl)ethyl]tetrazol-1-yl}alkanones.
    Rajasekaran A; Thampi PP
    Eur J Med Chem; 2005 Dec; 40(12):1359-64. PubMed ID: 16169128
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Synthesis of some quinoline-2(1H)-one and 1, 2, 4 - triazolo [ 4 , 3 -a ] quinoline derivatives as potent anticonvulsants.
    Guan LP; Jin QH; Tian GR; Chai KY; Quan ZS
    J Pharm Pharm Sci; 2007; 10(3):254-62. PubMed ID: 17727789
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Chronobiotic activity of N-[2-(2,7-dimethoxyfluoren-9-yl)ethyl]-propanamide. Synthesis and melatonergic pharmacology of fluoren-9-ylethyl amides.
    Epperson JR; Bruce MA; Catt JD; Deskus JA; Hodges DB; Karageorge GN; Keavy DJ; Mahle CD; Mattson RJ; Ortiz AA; Parker MF; Takaki KS; Watson BT; Joseph P Yevich
    Bioorg Med Chem; 2004 Sep; 12(17):4601-11. PubMed ID: 15358287
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Discovery of a novel sub-class of ROMK channel inhibitors typified by 5-(2-(4-(2-(4-(1H-Tetrazol-1-yl)phenyl)acetyl)piperazin-1-yl)ethyl)isobenzofuran-1(3H)-one.
    Tang H; de Jesus RK; Walsh SP; Zhu Y; Yan Y; Priest BT; Swensen AM; Alonso-Galicia M; Felix JP; Brochu RM; Bailey T; Thomas-Fowlkes B; Zhou X; Pai LY; Hampton C; Hernandez M; Owens K; Roy S; Kaczorowski GJ; Yang L; Garcia ML; Pasternak A
    Bioorg Med Chem Lett; 2013 Nov; 23(21):5829-32. PubMed ID: 24075732
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Small molecule Hedgehog pathway antagonists.
    Trinh TN; McLaughlin EA; Gordon CP; Bernstein IR; Pye VJ; Redgrove KA; McCluskey A
    Org Biomol Chem; 2017 Apr; 15(14):3046-3059. PubMed ID: 28318003
    [TBL] [Abstract][Full Text] [Related]  

  • 60. (R)-4-(4-fluorophenyl)-1-[2-hydroxy-2-(3-methyl-1-benzofuran-2-yl)ethyl]piperazinium chloride propan-1-ol solvate.
    Kurfürst P; Marek J; Vanco J; Csöllei J
    Acta Crystallogr C; 2004 Jul; 60(Pt 7):o494-5. PubMed ID: 15237174
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.