BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

200 related articles for article (PubMed ID: 15361844)

  • 21. Absence of p21 partially rescues Mdm4 loss and uncovers an antiproliferative effect of Mdm4 on cell growth.
    Steinman HA; Sluss HK; Sands AT; Pihan G; Jones SN
    Oncogene; 2004 Jan; 23(1):303-6. PubMed ID: 14712235
    [TBL] [Abstract][Full Text] [Related]  

  • 22. p53 Activity Dominates That of p73 upon Mdm4 Loss in Development and Tumorigenesis.
    Tashakori M; Zhang Y; Xiong S; You MJ; Lozano G
    Mol Cancer Res; 2016 Jan; 14(1):56-65. PubMed ID: 26527653
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Targeting the MDM2/MDM4 interaction interface as a promising approach for p53 reactivation therapy.
    Pellegrino M; Mancini F; Lucà R; Coletti A; Giacchè N; Manni I; Arisi I; Florenzano F; Teveroni E; Buttarelli M; Fici L; Brandi R; Bruno T; Fanciulli M; D'Onofrio M; Piaggio G; Pellicciari R; Pontecorvi A; Marine JC; Macchiarulo A; Moretti F
    Cancer Res; 2015 Nov; 75(21):4560-72. PubMed ID: 26359458
    [TBL] [Abstract][Full Text] [Related]  

  • 24. MDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response.
    Mancini F; Pieroni L; Monteleone V; Lucà R; Fici L; Luca E; Urbani A; Xiong S; Soddu S; Masetti R; Lozano G; Pontecorvi A; Moretti F
    Oncogene; 2016 Jan; 35(2):228-40. PubMed ID: 25961923
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53.
    Jones SN; Roe AE; Donehower LA; Bradley A
    Nature; 1995 Nov; 378(6553):206-8. PubMed ID: 7477327
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Mutant p53 is constitutively phosphorylated at Serine 15 in UV-induced mouse skin tumors: involvement of ERK1/2 MAP kinase.
    Melnikova VO; Santamaria AB; Bolshakov SV; Ananthaswamy HN
    Oncogene; 2003 Sep; 22(38):5958-66. PubMed ID: 12955074
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Downregulation of Mdm2 and Mdm4 enhances viral gene expression during adenovirus infection.
    Yang H; Zheng Z; Zhao LY; Li Q; Liao D
    Cell Cycle; 2012 Feb; 11(3):582-93. PubMed ID: 22262167
    [TBL] [Abstract][Full Text] [Related]  

  • 28. MDM4 (MDMX) overexpression enhances stabilization of stress-induced p53 and promotes apoptosis.
    Mancini F; Gentiletti F; D'Angelo M; Giglio S; Nanni S; D'Angelo C; Farsetti A; Citro G; Sacchi A; Pontecorvi A; Moretti F
    J Biol Chem; 2004 Feb; 279(9):8169-80. PubMed ID: 14660608
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The loss of mdm2 induces p53-mediated apoptosis.
    de Rozieres S; Maya R; Oren M; Lozano G
    Oncogene; 2000 Mar; 19(13):1691-7. PubMed ID: 10763826
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death.
    Boesten LS; Zadelaar SM; De Clercq S; Francoz S; van Nieuwkoop A; Biessen EA; Hofmann F; Feil S; Feil R; Jochemsen AG; Zurcher C; Havekes LM; van Vlijmen BJ; Marine JC
    Cell Death Differ; 2006 Dec; 13(12):2089-98. PubMed ID: 16729027
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Regulation of kidney development by the Mdm2/Mdm4-p53 axis.
    El-Dahr S; Hilliard S; Saifudeen Z
    J Mol Cell Biol; 2017 Feb; 9(1):26-33. PubMed ID: 28096292
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Augmented antitumor activity of 5-fluorouracil by double knockdown of MDM4 and MDM2 in colon and gastric cancer cells.
    Imanishi M; Yamamoto Y; Wang X; Sugaya A; Hirose M; Endo S; Natori Y; Yamato K; Hyodo I
    Cancer Sci; 2019 Feb; 110(2):639-649. PubMed ID: 30488540
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Disrupting TP53 in mouse models of human cancers.
    Parant JM; Lozano G
    Hum Mutat; 2003 Mar; 21(3):321-6. PubMed ID: 12619119
    [TBL] [Abstract][Full Text] [Related]  

  • 34. mdm2 deletion does not alter growth characteristics of p53-deficient embryo fibroblasts.
    McMasters KM; Montes de Oca Luna R; Peña JR; Lozano G
    Oncogene; 1996 Oct; 13(8):1731-6. PubMed ID: 8895519
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Phosphorylation of serine 18 regulates distinct p53 functions in mice.
    Sluss HK; Armata H; Gallant J; Jones SN
    Mol Cell Biol; 2004 Feb; 24(3):976-84. PubMed ID: 14729946
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.
    Honda R; Yasuda H
    EMBO J; 1999 Jan; 18(1):22-7. PubMed ID: 9878046
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Loss of oocytes due to conditional ablation of Murine double minute 2 (Mdm2) gene is p53-dependent and results in female sterility.
    Livera G; Uzbekov R; Jarrier P; Fouchécourt S; Duquenne C; Parent AS; Marine JC; Monget P
    FEBS Lett; 2016 Aug; 590(16):2566-74. PubMed ID: 27364741
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Loss of Mdm4 results in p53-dependent dilated cardiomyopathy.
    Xiong S; Van Pelt CS; Elizondo-Fraire AC; Fernandez-Garcia B; Lozano G
    Circulation; 2007 Jun; 115(23):2925-30. PubMed ID: 17533180
    [TBL] [Abstract][Full Text] [Related]  

  • 39. MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation.
    Qi DL; Cobrinik D
    Oncogene; 2017 Mar; 36(13):1760-1769. PubMed ID: 27748758
    [TBL] [Abstract][Full Text] [Related]  

  • 40. High levels of the p53 inhibitor MDM4 in head and neck squamous carcinomas.
    Valentin-Vega YA; Barboza JA; Chau GP; El-Naggar AK; Lozano G
    Hum Pathol; 2007 Oct; 38(10):1553-62. PubMed ID: 17651783
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.