BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

174 related articles for article (PubMed ID: 15364936)

  • 1. Recognition of phosphodegron motifs in human cyclin E by the SCF(Fbw7) ubiquitin ligase.
    Ye X; Nalepa G; Welcker M; Kessler BM; Spooner E; Qin J; Elledge SJ; Clurman BE; Harper JW
    J Biol Chem; 2004 Nov; 279(48):50110-9. PubMed ID: 15364936
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases.
    Hao B; Oehlmann S; Sowa ME; Harper JW; Pavletich NP
    Mol Cell; 2007 Apr; 26(1):131-43. PubMed ID: 17434132
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.
    Nakajima T; Kitagawa K; Ohhata T; Sakai S; Uchida C; Shibata K; Minegishi N; Yumimoto K; Nakayama KI; Masumoto K; Katou F; Niida H; Kitagawa M
    J Biol Chem; 2015 Apr; 290(16):10368-81. PubMed ID: 25670854
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fbw7α and Fbw7γ collaborate to shuttle cyclin E1 into the nucleolus for multiubiquitylation.
    Bhaskaran N; van Drogen F; Ng HF; Kumar R; Ekholm-Reed S; Peter M; Sangfelt O; Reed SI
    Mol Cell Biol; 2013 Jan; 33(1):85-97. PubMed ID: 23109421
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of APC(Cdh1) E3 ligase activity by the Fbw7/cyclin E signaling axis contributes to the tumor suppressor function of Fbw7.
    Lau AW; Inuzuka H; Fukushima H; Wan L; Liu P; Gao D; Sun Y; Wei W
    Cell Res; 2013 Jul; 23(7):947-61. PubMed ID: 23670162
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Isoform-specific SCF(Fbw7) ubiquitination mediates differential regulation of PGC-1α.
    Trausch-Azar JS; Abed M; Orian A; Schwartz AL
    J Cell Physiol; 2015 Apr; 230(4):842-52. PubMed ID: 25204433
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Nucleolar targeting of the fbw7 ubiquitin ligase by a pseudosubstrate and glycogen synthase kinase 3.
    Welcker M; Larimore EA; Frappier L; Clurman BE
    Mol Cell Biol; 2011 Mar; 31(6):1214-24. PubMed ID: 21220517
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase.
    Koepp DM; Schaefer LK; Ye X; Keyomarsi K; Chu C; Harper JW; Elledge SJ
    Science; 2001 Oct; 294(5540):173-7. PubMed ID: 11533444
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fbw7 isoform interaction contributes to cyclin E proteolysis.
    Zhang W; Koepp DM
    Mol Cancer Res; 2006 Dec; 4(12):935-43. PubMed ID: 17189384
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isoform- and cell cycle-dependent substrate degradation by the Fbw7 ubiquitin ligase.
    Grim JE; Gustafson MP; Hirata RK; Hagar AC; Swanger J; Welcker M; Hwang HC; Ericsson J; Russell DW; Clurman BE
    J Cell Biol; 2008 Jun; 181(6):913-20. PubMed ID: 18559665
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Ras activity regulates cyclin E degradation by the Fbw7 pathway.
    Minella AC; Welcker M; Clurman BE
    Proc Natl Acad Sci U S A; 2005 Jul; 102(27):9649-54. PubMed ID: 15980150
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cooperation between different Cdc4/Fbw7 isoforms may be associated with 2-step inactivation of SCF(Cdc4) targets.
    Reed SI
    Cell Cycle; 2006 Sep; 5(17):1923-4. PubMed ID: 16929178
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Both SCF(Cdc4alpha) and SCF(Cdc4gamma) are required for cyclin E turnover in cell lines that do not overexpress cyclin E.
    Sangfelt O; Cepeda D; Malyukova A; van Drogen F; Reed SI
    Cell Cycle; 2008 Apr; 7(8):1075-82. PubMed ID: 18414042
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7).
    Sundqvist A; Bengoechea-Alonso MT; Ye X; Lukiyanchuk V; Jin J; Harper JW; Ericsson J
    Cell Metab; 2005 Jun; 1(6):379-91. PubMed ID: 16054087
    [TBL] [Abstract][Full Text] [Related]  

  • 15. MiRNA-27a controls FBW7/hCDC4-dependent cyclin E degradation and cell cycle progression.
    Lerner M; Lundgren J; Akhoondi S; Jahn A; Ng HF; Akbari Moqadam F; Oude Vrielink JA; Agami R; Den Boer ML; Grandér D; Sangfelt O
    Cell Cycle; 2011 Jul; 10(13):2172-83. PubMed ID: 21597324
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphorylation-dependent degradation of c-Myc is mediated by the F-box protein Fbw7.
    Yada M; Hatakeyama S; Kamura T; Nishiyama M; Tsunematsu R; Imaki H; Ishida N; Okumura F; Nakayama K; Nakayama KI
    EMBO J; 2004 May; 23(10):2116-25. PubMed ID: 15103331
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.
    Kitagawa K; Hiramatsu Y; Uchida C; Isobe T; Hattori T; Oda T; Shibata K; Nakamura S; Kikuchi A; Kitagawa M
    Oncogene; 2009 Jun; 28(25):2393-405. PubMed ID: 19421138
    [TBL] [Abstract][Full Text] [Related]  

  • 18. p53 and SCFFbw7 cooperatively restrain cyclin E-associated genome instability.
    Minella AC; Grim JE; Welcker M; Clurman BE
    Oncogene; 2007 Oct; 26(48):6948-53. PubMed ID: 17486057
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4.
    Welcker M; Clurman BE
    J Biol Chem; 2005 Mar; 280(9):7654-8. PubMed ID: 15611062
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Triggering ubiquitination of a CDK inhibitor at origins of DNA replication.
    Furstenthal L; Swanson C; Kaiser BK; Eldridge AG; Jackson PK
    Nat Cell Biol; 2001 Aug; 3(8):715-22. PubMed ID: 11483956
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.