BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

259 related articles for article (PubMed ID: 1536570)

  • 1. 17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: a comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA.
    Spink DC; Eugster HP; Lincoln DW; Schuetz JD; Schuetz EG; Johnson JA; Kaminsky LS; Gierthy JF
    Arch Biochem Biophys; 1992 Mar; 293(2):342-8. PubMed ID: 1536570
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on estrogen metabolism in MCF-7 breast cancer cells: evidence for induction of a novel 17 beta-estradiol 4-hydroxylase.
    Spink DC; Hayes CL; Young NR; Christou M; Sutter TR; Jefcoate CR; Gierthy JF
    J Steroid Biochem Mol Biol; 1994 Dec; 51(5-6):251-8. PubMed ID: 7826886
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differential expression of CYP1A1 and CYP1B1 in human breast epithelial cells and breast tumor cells.
    Spink DC; Spink BC; Cao JQ; DePasquale JA; Pentecost BT; Fasco MJ; Li Y; Sutter TR
    Carcinogenesis; 1998 Feb; 19(2):291-8. PubMed ID: 9498279
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 2,3,7,8-Tetrachlorodibenzo-p-dioxin causes an extensive alteration of 17 beta-estradiol metabolism in MCF-7 breast tumor cells.
    Spink DC; Lincoln DW; Dickerman HW; Gierthy JF
    Proc Natl Acad Sci U S A; 1990 Sep; 87(17):6917-21. PubMed ID: 2395886
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 12-O-tetradecanoylphorbol-13-acetate upregulates the Ah receptor and differentially alters CYP1B1 and CYP1A1 expression in MCF-7 breast cancer cells.
    Spink BC; Fasco MJ; Gierthy JF; Spink DC
    J Cell Biochem; 1998 Sep; 70(3):289-96. PubMed ID: 9706865
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Induction of tamoxifen-4-hydroxylation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), beta-naphthoflavone (beta NF), and phenobarbital (PB) in avian liver: identification of P450 TCDDAA as catalyst of 4-hydroxylation induced by TCDD and beta NF.
    Kupfer D; Mani C; Lee CA; Rifkind AB
    Cancer Res; 1994 Jun; 54(12):3140-4. PubMed ID: 8205532
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolism of equilenin in MCF-7 and MDA-MB-231 human breast cancer cells.
    Spink DC; Zhang F; Hussain MM; Katz BH; Liu X; Hilker DR; Bolton JL
    Chem Res Toxicol; 2001 May; 14(5):572-81. PubMed ID: 11368557
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Co-expression of human CYP1A1 and a human analog of cytochrome P450-EF in response to 2,3,7,8-tetrachloro-dibenzo-p-dioxin in the human mammary carcinoma-derived MCF-7 cells.
    Christou M; Savas U; Spink DC; Gierthy JF; Jefcoate CR
    Carcinogenesis; 1994 Apr; 15(4):725-32. PubMed ID: 8149487
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Roles of cytochromes P450 1A2 and 3A4 in the oxidation of estradiol and estrone in human liver microsomes.
    Yamazaki H; Shaw PM; Guengerich FP; Shimada T
    Chem Res Toxicol; 1998 Jun; 11(6):659-65. PubMed ID: 9625734
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nature of cytochromes P450 involved in the 2-/4-hydroxylations of estradiol in human liver microsomes.
    Kerlan V; Dreano Y; Bercovici JP; Beaune PH; Floch HH; Berthou F
    Biochem Pharmacol; 1992 Nov; 44(9):1745-56. PubMed ID: 1449532
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1B1.
    Hayes CL; Spink DC; Spink BC; Cao JQ; Walker NJ; Sutter TR
    Proc Natl Acad Sci U S A; 1996 Sep; 93(18):9776-81. PubMed ID: 8790407
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of zearalenone on mRNA expression and activity of cytochrome P450 1A1 and 1B1 in MCF-7 cells.
    Yu Z; Hu D; Li Y
    Ecotoxicol Environ Saf; 2004 Jun; 58(2):187-93. PubMed ID: 15157572
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dioxin suppresses benzo[a]pyrene-induced mutations and DNA adduct formation through cytochrome P450 1A1 induction and (±)-anti-benzo[a]pyrene-7,8-diol-9,10-epoxide inactivation in human hepatoma cells.
    Shiizaki K; Kawanishi M; Yagi T
    Mutat Res; 2013 Jan; 750(1-2):77-85. PubMed ID: 23036853
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Different response of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-sensitive genes in human breast cancer MCF-7 and MDA-MB 231 cells.
    Döhr O; Vogel C; Abel J
    Arch Biochem Biophys; 1995 Aug; 321(2):405-12. PubMed ID: 7646066
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Differential regulation of cytochrome P450 1A1 and 1B1 by a combination of dioxin and pesticides in the breast tumor cell line MCF-7.
    Coumoul X; Diry M; Robillot C; Barouki R
    Cancer Res; 2001 May; 61(10):3942-8. PubMed ID: 11358810
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effect of dioxin and 17β-estradiol on the expression of cytochrome P450 1A1 gene via an estrogen receptor dependent pathway in cellular and xenografted models.
    Go RE; Hwang KA; Kim CW; Byun YS; Nam KH; Choi KC
    Environ Toxicol; 2017 Oct; 32(10):2225-2233. PubMed ID: 28618207
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Differential roles of cytochromes P450 2D1, 2C11, and 1A1/2 in the hydroxylation of bufuralol by rat liver microsomes.
    Mimura M; Yamazaki H; Sugahara C; Hiroi T; Funae Y; Shimada T
    Biochem Pharmacol; 1994 Jun; 47(11):1957-63. PubMed ID: 7912070
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Effect of chlorinated hydrocarbons on expression of cytochrome P450 1A1, 1A2 and 1B1 and 2- and 4-hydroxylation of 17beta-estradiol in female Sprague-Dawley rats.
    Badawi AF; Cavalieri EL; Rogan EG
    Carcinogenesis; 2000 Aug; 21(8):1593-9. PubMed ID: 10910964
    [TBL] [Abstract][Full Text] [Related]  

  • 19. 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2.
    Arlt VM; Hewer A; Sorg BL; Schmeiser HH; Phillips DH; Stiborova M
    Chem Res Toxicol; 2004 Aug; 17(8):1092-101. PubMed ID: 15310241
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism of action of alpha-naphthoflavone as an Ah receptor antagonist in MCF-7 human breast cancer cells.
    Merchant M; Krishnan V; Safe S
    Toxicol Appl Pharmacol; 1993 Jun; 120(2):179-85. PubMed ID: 8390116
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.