These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 15369396)

  • 1. Design, synthesis, and biological evaluation of biotin conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid for the isolation of the protein targets.
    Honda T; Janosik T; Honda Y; Han J; Liby KT; Williams CR; Couch RD; Anderson AC; Sporn MB; Gribble GW
    J Med Chem; 2004 Sep; 47(20):4923-32. PubMed ID: 15369396
    [TBL] [Abstract][Full Text] [Related]  

  • 2. CDDO-Me inhibits proliferation, induces apoptosis, down-regulates Akt, mTOR, NF-kappaB and NF-kappaB-regulated antiapoptotic and proangiogenic proteins in TRAMP prostate cancer cells.
    Deeb D; Gao X; Dulchavsky SA; Gautam SC
    J Exp Ther Oncol; 2008; 7(1):31-9. PubMed ID: 18472640
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthetic triterpenoids cooperate with tumor necrosis factor-related apoptosis-inducing ligand to induce apoptosis of breast cancer cells.
    Hyer ML; Croxton R; Krajewska M; Krajewski S; Kress CL; Lu M; Suh N; Sporn MB; Cryns VL; Zapata JM; Reed JC
    Cancer Res; 2005 Jun; 65(11):4799-808. PubMed ID: 15930300
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Apoptotic activity and mechanism of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic-acid and related synthetic triterpenoids in prostate cancer.
    Hyer ML; Shi R; Krajewska M; Meyer C; Lebedeva IV; Fisher PB; Reed JC
    Cancer Res; 2008 Apr; 68(8):2927-33. PubMed ID: 18413762
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2-Cyano-3,12-dioxoolean-1,9-dien-28-oic acid and related compounds inhibit growth of colon cancer cells through peroxisome proliferator-activated receptor gamma-dependent and -independent pathways.
    Chintharlapalli S; Papineni S; Konopleva M; Andreef M; Samudio I; Safe S
    Mol Pharmacol; 2005 Jul; 68(1):119-28. PubMed ID: 15798084
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia.
    Konopleva M; Tsao T; Estrov Z; Lee RM; Wang RY; Jackson CE; McQueen T; Monaco G; Munsell M; Belmont J; Kantarjian H; Sporn MB; Andreeff M
    Cancer Res; 2004 Nov; 64(21):7927-35. PubMed ID: 15520199
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 2-cyano-3,12-dioxooleana-1,9(11)-diene-28-oic acid disrupts microtubule polymerization: a possible mechanism contributing to apoptosis.
    Couch RD; Ganem NJ; Zhou M; Popov VM; Honda T; Veenstra TD; Sporn MB; Anderson AC
    Mol Pharmacol; 2006 Apr; 69(4):1158-65. PubMed ID: 16407469
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Growth-inhibitory effect of a novel synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid, on ovarian carcinoma cell lines not dependent on peroxisome proliferator-activated receptor-gamma expression.
    Melichar B; Konopleva M; Hu W; Melicharova K; Andreeff M; Freedman RS
    Gynecol Oncol; 2004 Apr; 93(1):149-54. PubMed ID: 15047229
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Efficient synthesis of (-)- and (+)-tricyclic compounds with enone functionalities in rings A and C. A novel class of orally active anti-inflammatory and cancer chemopreventive agents.
    Honda T; Favaloro FG; Janosik T; Honda Y; Suh N; Sporn MB; Gribble GW
    Org Biomol Chem; 2003 Dec; 1(24):4384-91. PubMed ID: 14685310
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potent protection against aflatoxin-induced tumorigenesis through induction of Nrf2-regulated pathways by the triterpenoid 1-[2-cyano-3-,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole.
    Yates MS; Kwak MK; Egner PA; Groopman JD; Bodreddigari S; Sutter TR; Baumgartner KJ; Roebuck BD; Liby KT; Yore MM; Honda T; Gribble GW; Sporn MB; Kensler TW
    Cancer Res; 2006 Feb; 66(4):2488-94. PubMed ID: 16489057
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The novel synthetic triterpenoid, CDDO-imidazolide, inhibits inflammatory response and tumor growth in vivo.
    Place AE; Suh N; Williams CR; Risingsong R; Honda T; Honda Y; Gribble GW; Leesnitzer LM; Stimmel JB; Willson TM; Rosen E; Sporn MB
    Clin Cancer Res; 2003 Jul; 9(7):2798-806. PubMed ID: 12855660
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and biological evaluation of amino acid methyl ester conjugates of 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid against the production of nitric oxide (NO).
    Onyango EO; Fu L; Cao M; Liby KT; Sporn MB; Gribble GW
    Bioorg Med Chem Lett; 2014 Jan; 24(2):532-4. PubMed ID: 24388806
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Triterpenoids as new promising anticancer drugs.
    Petronelli A; Pannitteri G; Testa U
    Anticancer Drugs; 2009 Nov; 20(10):880-92. PubMed ID: 19745720
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) induces apoptosis of human diffuse large B-cell lymphoma cells through a peroxisome proliferator-activated receptor gamma-independent pathway.
    Ray DM; Morse KM; Hilchey SP; Garcia TM; Felgar RE; Maggirwar SB; Phipps RP; Bernstein SH
    Exp Hematol; 2006 Sep; 34(9):1202-11. PubMed ID: 16939813
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Growth inhibition and apoptosis of human multiple myeloma cells induced by 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid derivatives.
    Rogers LJ; John T; Park J; Tucker M; Ma H; Wu Y; Rayalam S; Wang X
    Anticancer Drugs; 2020 Sep; 31(8):806-818. PubMed ID: 32304407
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CDDO-Me Elicits Anti-Breast Cancer Activity by Targeting LRP6 and FZD7 Receptor Complex.
    Zhou L; Wang Z; Yu S; Xiong Y; Fan J; Lyu Y; Su Z; Song J; Liu S; Sun Q; Lu D
    J Pharmacol Exp Ther; 2020 Apr; 373(1):149-159. PubMed ID: 32015160
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid and its derivatives elicit human lymphoid cell apoptosis through a novel pathway involving the unregulated mitochondrial permeability transition pore.
    Brookes PS; Morse K; Ray D; Tompkins A; Young SM; Hilchey S; Salim S; Konopleva M; Andreeff M; Phipps R; Bernstein SH
    Cancer Res; 2007 Feb; 67(4):1793-802. PubMed ID: 17308122
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and Anticancer Activity of CDDO and CDDO-Me, Two Derivatives of Natural Triterpenoids.
    Borella R; Forti L; Gibellini L; De Gaetano A; De Biasi S; Nasi M; Cossarizza A; Pinti M
    Molecules; 2019 Nov; 24(22):. PubMed ID: 31766211
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel dicyanotriterpenoid, 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-onitrile, active at picomolar concentrations for inhibition of nitric oxide production.
    Honda T; Honda Y; Favaloro FG; Gribble GW; Suh N; Place AE; Rendi MH; Sporn MB
    Bioorg Med Chem Lett; 2002 Apr; 12(7):1027-30. PubMed ID: 11909709
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells.
    Konopleva M; Zhang W; Shi YX; McQueen T; Tsao T; Abdelrahim M; Munsell MF; Johansen M; Yu D; Madden T; Safe SH; Hung MC; Andreeff M
    Mol Cancer Ther; 2006 Feb; 5(2):317-28. PubMed ID: 16505105
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.