These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Influence of O6-methylguanine on DNA damage and cytotoxicity of temozolomide in L1210 mouse leukemia sensitive and resistant to chloroethylnitrosoureas. Taverna P; Catapano CV; Citti L; Bonfanti M; D'Incalci M Anticancer Drugs; 1992 Aug; 3(4):401-5. PubMed ID: 1421437 [TBL] [Abstract][Full Text] [Related]
4. Expression of mammalian O6-alkylguanine-DNA alkyltransferase in a cell line sensitive to alkylating agents. Dolan ME; Norbeck L; Clyde C; Hora NK; Erickson LC; Pegg AE Carcinogenesis; 1989 Sep; 10(9):1613-9. PubMed ID: 2766456 [TBL] [Abstract][Full Text] [Related]
5. Relationships among cell survival, O6-alkylguanine-DNA alkyltransferase activity, and reactivation of methylated adenovirus 5 and herpes simplex virus type 1 in human melanoma cell lines. Maynard K; Parsons PG; Cerny T; Margison GP Cancer Res; 1989 Sep; 49(17):4813-7. PubMed ID: 2547518 [TBL] [Abstract][Full Text] [Related]
6. Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine. Kokkinakis DM; Ahmed MM; Chendil D; Moschel RC; Pegg AE Clin Cancer Res; 2003 Sep; 9(10 Pt 1):3801-7. PubMed ID: 14506174 [TBL] [Abstract][Full Text] [Related]
7. Cytotoxic and DNA-damaging effects of 1,2-bis(sulfonyl)hydrazines on human cells of the Mer+ and Mer- phenotype. Pratviel G; Shyam K; Sartorelli AC Cancer Biochem Biophys; 1989 Oct; 10(4):365-75. PubMed ID: 2620294 [TBL] [Abstract][Full Text] [Related]
8. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability. Dosch J; Kaina B Oncogene; 1996 Nov; 13(9):1927-35. PubMed ID: 8934539 [TBL] [Abstract][Full Text] [Related]
9. Effect of O6-benzylguanine analogues on sensitivity of human tumor cells to the cytotoxic effects of alkylating agents. Dolan ME; Mitchell RB; Mummert C; Moschel RC; Pegg AE Cancer Res; 1991 Jul; 51(13):3367-72. PubMed ID: 1647266 [TBL] [Abstract][Full Text] [Related]
10. DNA damage induced by a new 2-chloroethyl nitrosourea on malignant melanoma cells. Godeneche D; Rapp M; Thierry A; Laval F; Madelmont JC; Chollet P; Veyre A Cancer Res; 1990 Sep; 50(18):5898-903. PubMed ID: 2393861 [TBL] [Abstract][Full Text] [Related]
11. Enhancement of nitrosourea activity in medulloblastoma and glioblastoma multiforme. Friedman HS; Dolan ME; Moschel RC; Pegg AE; Felker GM; Rich J; Bigner DD; Schold SC J Natl Cancer Inst; 1992 Dec; 84(24):1926-31. PubMed ID: 1334154 [TBL] [Abstract][Full Text] [Related]
12. Extended depletion of O6-methylguanine-DNA methyltransferase activity following O6-benzyl-2'-deoxyguanosine or O6-benzylguanine combined with streptozotocin treatment enhances 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity. Marathi UK; Dolan ME; Erickson LC Cancer Res; 1994 Aug; 54(16):4371-5. PubMed ID: 8044784 [TBL] [Abstract][Full Text] [Related]
13. A human cell line proficient in O6-methylguanine-DNA-methyltransferase and hypersensitive to alkylating agents. Lefebvre P; Laval F Carcinogenesis; 1993 Aug; 14(8):1671-5. PubMed ID: 8394782 [TBL] [Abstract][Full Text] [Related]
14. Mismatch repair mutations override alkyltransferase in conferring resistance to temozolomide but not to 1,3-bis(2-chloroethyl)nitrosourea. Liu L; Markowitz S; Gerson SL Cancer Res; 1996 Dec; 56(23):5375-9. PubMed ID: 8968088 [TBL] [Abstract][Full Text] [Related]
15. Transfectant CHO cells expressing O6-alkylguanine-DNA-alkyltransferase display increased resistance to DNA damage other than O6-guanine alkylation. Barrows LR; Borchers AH; Paxton MB Carcinogenesis; 1987 Dec; 8(12):1853-9. PubMed ID: 2824084 [TBL] [Abstract][Full Text] [Related]
16. Isolation of clones displaying enhanced resistance to methylating agents in O6-methylguanine-DNA methyltransferase-proficient CHO cells. Aquilina G; Frosina G; Zijno A; Di Muccio A; Dogliotti E; Abbondandolo A; Bignami M Carcinogenesis; 1988 Jul; 9(7):1217-22. PubMed ID: 3383340 [TBL] [Abstract][Full Text] [Related]
17. [Modulation of the antitumor activity of 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosoure a by O(6)-methyl-2'-deoxyguanosine--a new inhibitor of O(6)-alkylguanine-DNA-alkyltransferase]. Dederer LIu; Sokolova IS; Bakhmedova AA; Miniker TD; Mel'nik SIa; Gorbacheva LB Biokhimiia; 1995 Sep; 60(9):1521-9. PubMed ID: 8562657 [TBL] [Abstract][Full Text] [Related]
18. Tetrazepinones are equally cytotoxic to Mer+ and Mer- human tumor cell lines. Jean-Claude BJ; Mustafa A; Watson AJ; Damian Z; Vasilescu D; Chan TH; Leyland-Jones B J Pharmacol Exp Ther; 1999 Feb; 288(2):484-9. PubMed ID: 9918549 [TBL] [Abstract][Full Text] [Related]
19. N-methyl-N'-nitro-N-nitrosoguanidine-resistant HeLa S3 cells still have little O6-methylguanine-DNA methyltransferase activity and are hypermutable by alkylating agents. Ishida R; Takahashi T Carcinogenesis; 1987 Aug; 8(8):1109-13. PubMed ID: 3608093 [TBL] [Abstract][Full Text] [Related]
20. O6-methylguanine as a modulator of antitumor activity of N-alkyl-N-nitrosoureas in vivo. Gorbacheva LB; Kukushkina GV; Elksne SJ; Miniker TD; Melnik SYa ; Preobrazhenskaya MN Anticancer Drugs; 1991 Apr; 2(2):185-9. PubMed ID: 1958863 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]