167 related articles for article (PubMed ID: 15379215)
1. A 771726, the active metabolite of leflunomide, inhibits TNF-alpha and IL-1 from Kupffer cells.
Yao HW; Li J; Chen JQ; Xu SY
Inflammation; 2004 Apr; 28(2):97-103. PubMed ID: 15379215
[TBL] [Abstract][Full Text] [Related]
2. Leflunomide attenuates hepatocyte injury by inhibiting Kupffer cells.
Yao HW; Li J; Chen JQ; Xu SY
World J Gastroenterol; 2004 Jun; 10(11):1608-11. PubMed ID: 15162534
[TBL] [Abstract][Full Text] [Related]
3. [The active metabolite of leflunomide A771726 inhibits proliferation and collagen synthesis of hepatic stellate cell].
Yao HW; Li J; Chen JQ; Xu SY
Zhejiang Da Xue Xue Bao Yi Xue Ban; 2004 Nov; 33(6):515-8, 528. PubMed ID: 15586409
[TBL] [Abstract][Full Text] [Related]
4. Effect and mechanisms of FR167653, a dual inhibitor of TNF-alpha and IL-1, on BCG plus LPS induced-liver injury.
Yao HW; Yue L
Inflamm Res; 2005 Nov; 54(11):471-7. PubMed ID: 16307221
[TBL] [Abstract][Full Text] [Related]
5. Direct cell-to-cell contact between Kupffer cells and hepatocytes augments endotoxin-induced hepatic injury.
Hoebe KH; Witkamp RF; Fink-Gremmels J; Van Miert AS; Monshouwer M
Am J Physiol Gastrointest Liver Physiol; 2001 Apr; 280(4):G720-8. PubMed ID: 11254499
[TBL] [Abstract][Full Text] [Related]
6. Suppressive effect of leflunomide on rat hepatic stellate cell proliferation involves on PDGF-BB-elicited activation of three mitogen-activated protein kinases.
Si HF; Lv X; Guo A; Jiang H; Li J
Cytokine; 2008 Apr; 42(1):24-31. PubMed ID: 18343153
[TBL] [Abstract][Full Text] [Related]
7. Naofen promotes TNF-α-mediated apoptosis of hepatocytes by activating caspase-3 in lipopolysaccharide-treated rats.
Fan JH; Feng GG; Huang L; Tang GD; Jiang HX; Xu J
World J Gastroenterol; 2014 May; 20(17):4963-71. PubMed ID: 24803807
[TBL] [Abstract][Full Text] [Related]
8. Active leflunomide metabolite inhibits interleukin 1beta, tumour necrosis factor alpha, nitric oxide, and metalloproteinase-3 production in activated human synovial tissue cultures.
Elkayam O; Yaron I; Shirazi I; Judovitch R; Caspi D; Yaron M
Ann Rheum Dis; 2003 May; 62(5):440-3. PubMed ID: 12695157
[TBL] [Abstract][Full Text] [Related]
9. Immunosuppressive leflunomide metabolite (A77 1726) blocks TNF-dependent nuclear factor-kappa B activation and gene expression.
Manna SK; Aggarwal BB
J Immunol; 1999 Feb; 162(4):2095-102. PubMed ID: 9973483
[TBL] [Abstract][Full Text] [Related]
10. [Role of p38MAPK signal transduction pathway in Kupffer cells production of TNF-alpha and IL-1beta in severely burned rats].
Chen XL; Xia ZF; Wei D; Ben DF; Wang YJ
Zhonghua Wai Ke Za Zhi; 2005 Feb; 43(3):185-8. PubMed ID: 15842901
[TBL] [Abstract][Full Text] [Related]
11. Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells.
Stadler J; Harbrecht BG; Di Silvio M; Curran RD; Jordan ML; Simmons RL; Billiar TR
J Leukoc Biol; 1993 Feb; 53(2):165-72. PubMed ID: 8445328
[TBL] [Abstract][Full Text] [Related]
12. The active metabolite of leflunomide, A771726, inhibits both the generation of and the bone-resorbing activity of osteoclasts by acting directly on cells of the osteoclast lineage.
Kobayashi Y; Ueyama S; Arai Y; Yoshida Y; Kaneda T; Sato T; Shin K; Kumegawa M; Hakeda Y
J Bone Miner Metab; 2004; 22(4):318-28. PubMed ID: 15221489
[TBL] [Abstract][Full Text] [Related]
13. Induction of anaphylatoxin C5a receptors in rat hepatocytes by lipopolysaccharide in vivo: mediation by interleukin-6 from Kupffer cells.
Koleva M; Schlaf G; Landmann R; Götze O; Jungermann K; Schieferdecker HL
Gastroenterology; 2002 Mar; 122(3):697-708. PubMed ID: 11875003
[TBL] [Abstract][Full Text] [Related]
14. [Effects of leflunomide and its active metabolite on the production and mRNA expression of TNF-alpha in peritoneal macrophages and synovial cells with adjuvant arthritis in rats].
Li WD; Lin ZB
Yao Xue Xue Bao; 2002 Oct; 37(10):767-70. PubMed ID: 12567858
[TBL] [Abstract][Full Text] [Related]
15. Mesenchymal stromal cell-dependent reprogramming of Kupffer cells is mediated by TNF-α and PGE2 and is crucial for liver transplant tolerance.
You Y; Zhang J; Gong J; Chen Y; Li Y; Yang K; Liu Z
Immunol Res; 2015 Jul; 62(3):292-305. PubMed ID: 25982496
[TBL] [Abstract][Full Text] [Related]
16. A771726, the active metabolite of leflunomide, directly inhibits the activity of cyclo-oxygenase-2 in vitro and in vivo in a substrate-sensitive manner.
Hamilton LC; Vojnovic I; Warner TD
Br J Pharmacol; 1999 Aug; 127(7):1589-96. PubMed ID: 10455314
[TBL] [Abstract][Full Text] [Related]
17. An active metabolite of leflunomide, A77 1726, inhibits the production of serum amyloid A protein in human hepatocytes.
Migita K; Miyashita T; Maeda Y; Nakamura M; Yatsuhashi H; Ishibashi H; Eguchi K
Rheumatology (Oxford); 2005 Apr; 44(4):443-8. PubMed ID: 15695308
[TBL] [Abstract][Full Text] [Related]
18. Lead stimulates intercellular signalling between hepatocytes and Kupffer cells.
Milosevic N; Maier P
Eur J Pharmacol; 2000 Aug; 401(3):317-28. PubMed ID: 10936489
[TBL] [Abstract][Full Text] [Related]
19. Role of Kupffer cells in lung injury in rats administered endotoxin 1.
Kono H; Fujii H; Amemiya H; Asakawa M; Hirai Y; Maki A; Tsuchiya M; Matsuda M; Yamamoto M
J Surg Res; 2005 Dec; 129(2):176-89. PubMed ID: 16112135
[TBL] [Abstract][Full Text] [Related]
20. The active metabolite of leflunomide, A77 1726, increases the production of IL-1 receptor antagonist in human synovial fibroblasts and articular chondrocytes.
Palmer G; Burger D; Mezin F; Magne D; Gabay C; Dayer JM; Guerne PA
Arthritis Res Ther; 2004; 6(3):R181-9. PubMed ID: 15142263
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
