These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 15379664)

  • 1. The use of radiolabeled compounds for ADME studies in discovery and exploratory development.
    Marathe PH; Shyu WC; Humphreys WG
    Curr Pharm Des; 2004; 10(24):2991-3008. PubMed ID: 15379664
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Radiolabeled absorption, distribution, metabolism, and excretion studies in drug development: why, when, and how?
    Penner N; Xu L; Prakash C
    Chem Res Toxicol; 2012 Mar; 25(3):513-31. PubMed ID: 22309195
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Use of radiolabeled compounds in drug metabolism and pharmacokinetic studies.
    Isin EM; Elmore CS; Nilsson GN; Thompson RA; Weidolf L
    Chem Res Toxicol; 2012 Mar; 25(3):532-42. PubMed ID: 22372867
    [TBL] [Abstract][Full Text] [Related]  

  • 4. What is the objective of the mass balance study? A retrospective analysis of data in animal and human excretion studies employing radiolabeled drugs.
    Roffey SJ; Obach RS; Gedge JI; Smith DA
    Drug Metab Rev; 2007; 39(1):17-43. PubMed ID: 17364879
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Use of radioactive compounds and autoradiography to determine drug tissue distribution.
    Solon EG
    Chem Res Toxicol; 2012 Mar; 25(3):543-55. PubMed ID: 22280496
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Radiolabeled mass-balance excretion and metabolism studies in laboratory animals: a commentary on why they are still necessary.
    White RE; Evans DC; Hop CE; Moore DJ; Prakash C; Surapaneni S; Tse FL
    Xenobiotica; 2013 Feb; 43(2):219-25; discussion 226-7. PubMed ID: 22803803
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolic stability for drug discovery and development: pharmacokinetic and biochemical challenges.
    Masimirembwa CM; Bredberg U; Andersson TB
    Clin Pharmacokinet; 2003; 42(6):515-28. PubMed ID: 12793837
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mini-Review: Comprehensive Drug Disposition Knowledge Generated in the Modern Human Radiolabeled ADME Study.
    Spracklin DK; Chen D; Bergman AJ; Callegari E; Obach RS
    CPT Pharmacometrics Syst Pharmacol; 2020 Aug; 9(8):428-434. PubMed ID: 32562380
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Can the Internet help to meet the challenges in ADME and e-ADME?
    Van de Waterbeemd H; De Groot M
    SAR QSAR Environ Res; 2002; 13(3-4):391-401. PubMed ID: 12184380
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Improving early drug discovery through ADME modelling: an overview.
    Wishart DS
    Drugs R D; 2007; 8(6):349-62. PubMed ID: 17963426
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Applications of high-throughput ADME in drug discovery.
    Kassel DB
    Curr Opin Chem Biol; 2004 Jun; 8(3):339-45. PubMed ID: 15183334
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Optimizing Oral Bioavailability in Drug Discovery: An Overview of Design and Testing Strategies and Formulation Options.
    Aungst BJ
    J Pharm Sci; 2017 Apr; 106(4):921-929. PubMed ID: 27986598
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Recent advances in the applications of radioisotopes in drug metabolism, toxicology and pharmacokinetics.
    Dalvie D
    Curr Pharm Des; 2000 Jul; 6(10):1009-28. PubMed ID: 10828299
    [TBL] [Abstract][Full Text] [Related]  

  • 14. In silico ADME-Tox modeling: progress and prospects.
    Alqahtani S
    Expert Opin Drug Metab Toxicol; 2017 Nov; 13(11):1147-1158. PubMed ID: 28988506
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Membrane transporters in drug development.
    Keogh JP
    Adv Pharmacol; 2012; 63():1-42. PubMed ID: 22776638
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitigating permeability-mediated risks in drug discovery.
    Wang J; Skolnik S
    Expert Opin Drug Metab Toxicol; 2010 Feb; 6(2):171-87. PubMed ID: 20064074
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Systems-ADME/Tox: resources and network approaches.
    Ekins S
    J Pharmacol Toxicol Methods; 2006; 53(1):38-66. PubMed ID: 16054403
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Using in vitro human tissues to predict pharmacokinetic properties.
    Huebert ND; Dasgupta M; Chen Y
    Curr Opin Drug Discov Devel; 2004 Jan; 7(1):69-74. PubMed ID: 14982150
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel strategies for microdose studies using non-radiolabeled compounds.
    Maeda K; Sugiyama Y
    Adv Drug Deliv Rev; 2011 Jun; 63(7):532-8. PubMed ID: 21345359
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 13.