BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

241 related articles for article (PubMed ID: 15385537)

  • 1. Regulation of WRN helicase activity in human base excision repair.
    Ahn B; Harrigan JA; Indig FE; Wilson DM; Bohr VA
    J Biol Chem; 2004 Dec; 279(51):53465-74. PubMed ID: 15385537
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Werner syndrome protein stimulates DNA polymerase beta strand displacement synthesis via its helicase activity.
    Harrigan JA; Opresko PL; von Kobbe C; Kedar PS; Prasad R; Wilson SH; Bohr VA
    J Biol Chem; 2003 Jun; 278(25):22686-95. PubMed ID: 12665521
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta.
    Harrigan JA; Wilson DM; Prasad R; Opresko PL; Beck G; May A; Wilson SH; Bohr VA
    Nucleic Acids Res; 2006; 34(2):745-54. PubMed ID: 16449207
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Competition between the DNA unwinding and strand pairing activities of the Werner and Bloom syndrome proteins.
    Machwe A; Lozada EM; Xiao L; Orren DK
    BMC Mol Biol; 2006 Jan; 7():1. PubMed ID: 16412221
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Coordinate action of the helicase and 3' to 5' exonuclease of Werner syndrome protein.
    Opresko PL; Laine JP; Brosh RM; Seidman MM; Bohr VA
    J Biol Chem; 2001 Nov; 276(48):44677-87. PubMed ID: 11572872
    [TBL] [Abstract][Full Text] [Related]  

  • 6. WRN, the protein deficient in Werner syndrome, plays a critical structural role in optimizing DNA repair.
    Chen L; Huang S; Lee L; Davalos A; Schiestl RH; Campisi J; Oshima J
    Aging Cell; 2003 Aug; 2(4):191-9. PubMed ID: 12934712
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Requirements for the nucleolytic processing of DNA ends by the Werner syndrome protein-Ku70/80 complex.
    Li B; Comai L
    J Biol Chem; 2001 Mar; 276(13):9896-902. PubMed ID: 11152456
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Biochemical and kinetic characterization of the DNA helicase and exonuclease activities of werner syndrome protein.
    Choudhary S; Sommers JA; Brosh RM
    J Biol Chem; 2004 Aug; 279(33):34603-13. PubMed ID: 15187093
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Human base excision repair enzymes apurinic/apyrimidinic endonuclease1 (APE1), DNA polymerase beta and poly(ADP-ribose) polymerase 1: interplay between strand-displacement DNA synthesis and proofreading exonuclease activity.
    Sukhanova MV; Khodyreva SN; Lebedeva NA; Prasad R; Wilson SH; Lavrik OI
    Nucleic Acids Res; 2005; 33(4):1222-9. PubMed ID: 15731342
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nuclear DNA helicase II (RNA helicase A) interacts with Werner syndrome helicase and stimulates its exonuclease activity.
    Friedemann J; Grosse F; Zhang S
    J Biol Chem; 2005 Sep; 280(35):31303-13. PubMed ID: 15995249
    [TBL] [Abstract][Full Text] [Related]  

  • 11. POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substrates.
    Opresko PL; Mason PA; Podell ER; Lei M; Hickson ID; Cech TR; Bohr VA
    J Biol Chem; 2005 Sep; 280(37):32069-80. PubMed ID: 16030011
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence.
    Kamath-Loeb AS; Loeb LA; Johansson E; Burgers PM; Fry M
    J Biol Chem; 2001 May; 276(19):16439-46. PubMed ID: 11279038
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Werner protein is a target of DNA-dependent protein kinase in vivo and in vitro, and its catalytic activities are regulated by phosphorylation.
    Karmakar P; Piotrowski J; Brosh RM; Sommers JA; Miller SP; Cheng WH; Snowden CM; Ramsden DA; Bohr VA
    J Biol Chem; 2002 May; 277(21):18291-302. PubMed ID: 11889123
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Base excision repair in nucleosomes lacking histone tails.
    Beard BC; Stevenson JJ; Wilson SH; Smerdon MJ
    DNA Repair (Amst); 2005 Feb; 4(2):203-9. PubMed ID: 15590328
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A.
    Choudhary S; Doherty KM; Handy CJ; Sayer JM; Yagi H; Jerina DM; Brosh RM
    J Biol Chem; 2006 Mar; 281(9):6000-9. PubMed ID: 16380375
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Werner syndrome protein: biochemical properties and functional interactions.
    Bohr VA; Cooper M; Orren D; Machwe A; Piotrowski J; Sommers J; Karmakar P; Brosh R
    Exp Gerontol; 2000 Sep; 35(6-7):695-702. PubMed ID: 11053659
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism of Werner DNA helicase: POT1 and RPA stimulates WRN to unwind beyond gaps in the translocating strand.
    Ahn B; Lee JW; Jung H; Beck G; Bohr VA
    PLoS One; 2009; 4(3):e4673. PubMed ID: 19262689
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The N-terminal domain of the large subunit of human replication protein A binds to Werner syndrome protein and stimulates helicase activity.
    Shen JC; Lao Y; Kamath-Loeb A; Wold MS; Loeb LA
    Mech Ageing Dev; 2003; 124(8-9):921-30. PubMed ID: 14499497
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Poly(ADP-ribose) polymerase 1 regulates both the exonuclease and helicase activities of the Werner syndrome protein.
    von Kobbe C; Harrigan JA; Schreiber V; Stiegler P; Piotrowski J; Dawut L; Bohr VA
    Nucleic Acids Res; 2004; 32(13):4003-14. PubMed ID: 15292449
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Diverse dealings of the Werner helicase/nuclease.
    Cheng WH; Bohr VA
    Sci Aging Knowledge Environ; 2003 Aug; 2003(31):PE22. PubMed ID: 12904570
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.