161 related articles for article (PubMed ID: 15388586)
1. Adaphostin-induced apoptosis in CLL B cells is associated with induction of oxidative stress and exhibits synergy with fludarabine.
Shanafelt TD; Lee YK; Bone ND; Strege AK; Narayanan VL; Sausville EA; Geyer SM; Kaufmann SH; Kay NE
Blood; 2005 Mar; 105(5):2099-106. PubMed ID: 15388586
[TBL] [Abstract][Full Text] [Related]
2. Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells.
Chandra J; Hackbarth J; Le S; Loegering D; Bone N; Bruzek LM; Narayanan VL; Adjei AA; Kay NE; Tefferi A; Karp JE; Sausville EA; Kaufmann SH
Blood; 2003 Dec; 102(13):4512-9. PubMed ID: 12920036
[TBL] [Abstract][Full Text] [Related]
3. Naja nigricollis CMS-9 enhances the mitochondria-mediated death pathway in adaphostin-treated human leukaemia U937 cells.
Chen YJ; Wang JJ; Chang LS
Clin Exp Pharmacol Physiol; 2011 Nov; 38(11):755-63. PubMed ID: 21824174
[TBL] [Abstract][Full Text] [Related]
4. Adaphostin and bortezomib induce oxidative injury and apoptosis in imatinib mesylate-resistant hematopoietic cells expressing mutant forms of Bcr/Abl.
Dasmahapatra G; Nguyen TK; Dent P; Grant S
Leuk Res; 2006 Oct; 30(10):1263-72. PubMed ID: 16481037
[TBL] [Abstract][Full Text] [Related]
5. Adaphostin cytoxicity in glioblastoma cells is ROS-dependent and is accompanied by upregulation of heme oxygenase-1.
Long J; Manchandia T; Ban K; Gao S; Miller C; Chandra J
Cancer Chemother Pharmacol; 2007 Mar; 59(4):527-35. PubMed ID: 16924499
[TBL] [Abstract][Full Text] [Related]
6. Adaphostin-induced oxidative stress overcomes BCR/ABL mutation-dependent and -independent imatinib resistance.
Chandra J; Tracy J; Loegering D; Flatten K; Verstovsek S; Beran M; Gorre M; Estrov Z; Donato N; Talpaz M; Sawyers C; Bhalla K; Karp J; Sausville E; Kaufmann SH
Blood; 2006 Mar; 107(6):2501-6. PubMed ID: 16291594
[TBL] [Abstract][Full Text] [Related]
7. Adaphostin has significant and selective activity against chronic and acute myeloid leukemia cells.
Orsolic N; Golemovic M; Quintás-Cardama A; Scappini B; Manshouri T; Chandra J; Basic I; Giles F; Kantarjian H; Verstovsek S
Cancer Sci; 2006 Sep; 97(9):952-60. PubMed ID: 16822295
[TBL] [Abstract][Full Text] [Related]
8. CD40 triggering enhances fludarabine-induced apoptosis of chronic lymphocytic leukemia B-cells through autocrine release of tumor necrosis factor-alpha and interferon-gama and tumor necrosis factor receptor-I-II upregulation.
de Totero D; Tazzari PL; Capaia M; Montera MP; Clavio M; Balleari E; Foa R; Gobbi M
Haematologica; 2003 Feb; 88(2):148-58. PubMed ID: 12604404
[TBL] [Abstract][Full Text] [Related]
9. The tyrphostin adaphostin interacts synergistically with proteasome inhibitors to induce apoptosis in human leukemia cells through a reactive oxygen species (ROS)-dependent mechanism.
Dasmahapatra G; Rahmani M; Dent P; Grant S
Blood; 2006 Jan; 107(1):232-40. PubMed ID: 16166589
[TBL] [Abstract][Full Text] [Related]
10. Induction of apoptosis in human leukemia cells by the tyrosine kinase inhibitor adaphostin proceeds through a RAF-1/MEK/ERK- and AKT-dependent process.
Yu C; Rahmani M; Almenara J; Sausville EA; Dent P; Grant S
Oncogene; 2004 Feb; 23(7):1364-76. PubMed ID: 14647418
[TBL] [Abstract][Full Text] [Related]
11. Combinatorial effects of histone deacetylase inhibitors (HDACi), vorinostat and entinostat, and adaphostin are characterized by distinct redox alterations.
Rivera-Del Valle N; Cheng T; Irwin ME; Donnella H; Singh MM; Chandra J
Cancer Chemother Pharmacol; 2018 Mar; 81(3):483-495. PubMed ID: 29313067
[TBL] [Abstract][Full Text] [Related]
12. ZGDHu-1 and fludarabine have a synergistic effect on apoptosis of chronic lymphocytic leukemia cells.
Qiu L; Liu J; Wang Z; Hu W; Huang Q; Zhou Y
Oncol Rep; 2015 Sep; 34(3):1239-48. PubMed ID: 26165829
[TBL] [Abstract][Full Text] [Related]
13. Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism.
Trachootham D; Zhang H; Zhang W; Feng L; Du M; Zhou Y; Chen Z; Pelicano H; Plunkett W; Wierda WG; Keating MJ; Huang P
Blood; 2008 Sep; 112(5):1912-22. PubMed ID: 18574029
[TBL] [Abstract][Full Text] [Related]
14. Drug-induced apoptosis in chronic lymphocytic leukemia.
Stoetzer OJ; Pogrebniak A; Scholz M; Pelka-Fleischer R; Gullis E; Darsow M; Nüssler V; Wilmanns W
Leukemia; 1999 Nov; 13(11):1873-80. PubMed ID: 10557065
[TBL] [Abstract][Full Text] [Related]
15. Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells.
Palazzo AL; Evensen E; Huang YW; Cesano A; Nolan GP; Fantl WJ
PLoS One; 2011; 6(10):e24592. PubMed ID: 22016760
[TBL] [Abstract][Full Text] [Related]
16. In vitro evaluation of fludarabine in combination with cyclophosphamide and/or mitoxantrone in B-cell chronic lymphocytic leukemia.
Bellosillo B; Villamor N; Colomer D; Pons G; Montserrat E; Gil J
Blood; 1999 Oct; 94(8):2836-43. PubMed ID: 10515887
[TBL] [Abstract][Full Text] [Related]
17. The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells.
Battle TE; Arbiser J; Frank DA
Blood; 2005 Jul; 106(2):690-7. PubMed ID: 15802533
[TBL] [Abstract][Full Text] [Related]
18. Adaphostin toxicity in a sensitive non-small cell lung cancer model is mediated through Nrf2 signaling and heme oxygenase 1.
Fer ND; Shoemaker RH; Monks A
J Exp Clin Cancer Res; 2010 Jul; 29(1):91. PubMed ID: 20618971
[TBL] [Abstract][Full Text] [Related]
19. Modulation of IL-4 level by fludarabine and its relation to apoptosis in chronic B-cell lymphocytic leukemia.
Shamaa LA; Hussein Ael-S; Balbaa OA; Farahat NM; Ali MA
Egypt J Immunol; 2008; 15(1):181-92. PubMed ID: 20306682
[TBL] [Abstract][Full Text] [Related]
20. The investigational agent MLN2238 induces apoptosis and is cytotoxic to CLL cells in vitro, as a single agent and in combination with other drugs.
Paulus A; Masood A; Miller KC; Khan AN; Akhtar D; Advani P; Foran J; Rivera C; Roy V; Colon-Otero G; Chitta K; Chanan-Khan A
Br J Haematol; 2014 Apr; 165(1):78-88. PubMed ID: 24467634
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]