BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

179 related articles for article (PubMed ID: 1543525)

  • 1. Inhibition of T4 DNA ligase activity by (+)-CC-1065: demonstration of the importance of the stiffening and winding effects of (+)-CC-1065 on DNA.
    Sun D; Hurley LH
    Anticancer Drug Des; 1992 Feb; 7(1):15-36. PubMed ID: 1543525
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Determination of the structural features of (+)-CC-1065 that are responsible for bending and winding of DNA.
    Lee CS; Sun D; Kizu R; Hurley LH
    Chem Res Toxicol; 1991; 4(2):203-13. PubMed ID: 1782349
    [TBL] [Abstract][Full Text] [Related]  

  • 3. (+)-CC-1065 as a probe for intrinsic and protein-induced bending of DNA.
    Hurley LH; Sun D
    J Mol Recognit; 1994 Jun; 7(2):123-32. PubMed ID: 7826672
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-activity relationships of (+)-CC-1065 analogues in the inhibition of helicase-catalyzed unwinding of duplex DNA.
    Sun D; Hurley LH
    J Med Chem; 1992 May; 35(10):1773-82. PubMed ID: 1588557
    [TBL] [Abstract][Full Text] [Related]  

  • 5. DNA interstrand cross-linking, DNA sequence specificity, and induced conformational changes produced by a dimeric analog of (+)-CC-1065.
    Ding ZM; Hurley LH
    Anticancer Drug Des; 1991 Nov; 6(5):427-52. PubMed ID: 1662513
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of the (+)-CC-1065-(N3-adenine)DNA adduct on in vitro DNA synthesis mediated by Escherichia coli DNA polymerase.
    Sun D; Hurley LH
    Biochemistry; 1992 Mar; 31(10):2822-9. PubMed ID: 1547223
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism of interaction of CC-1065 (NSC 298223) with DNA.
    Swenson DH; Li LH; Hurley LH; Rokem JS; Petzold GL; Dayton BD; Wallace TL; Lin AH; Krueger WC
    Cancer Res; 1982 Jul; 42(7):2821-8. PubMed ID: 7083173
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Solution conformation of the (-)-cis-anti-benzo[a]pyrenyl-dG adduct opposite dC in a DNA duplex: intercalation of the covalently attached BP ring into the helix with base displacement of the modified deoxyguanosine into the major groove.
    Cosman M; Hingerty BE; Luneva N; Amin S; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1996 Jul; 35(30):9850-63. PubMed ID: 8703959
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Solution structure of the covalent duocarmycin A-DNA duplex complex.
    Lin CH; Patel DJ
    J Mol Biol; 1995 Apr; 248(1):162-79. PubMed ID: 7731041
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Demonstration of the asymmetric effect of CC-1065 on local DNA structure using a site-directed adduct in a 117-base-pair fragment from M13mp1.
    Hurley LH; Needham-VanDevanter DR; Lee CS
    Proc Natl Acad Sci U S A; 1987 Sep; 84(18):6412-6. PubMed ID: 2819875
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reaction of the antitumor antibiotic CC-1065 with DNA. Location of the site of thermally induced strand breakage and analysis of DNA sequence specificity.
    Reynolds VL; Molineux IJ; Kaplan DJ; Swenson DH; Hurley LH
    Biochemistry; 1985 Oct; 24(22):6228-37. PubMed ID: 3002434
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural distortions induced by integration host factor (IHF) at the H' site of phage lambda probed by (+)-CC-1065, pluramycin, and KMnO4 and by DNA cyclization studies.
    Sun D; Hurley LH; Harshey RM
    Biochemistry; 1996 Aug; 35(33):10815-27. PubMed ID: 8718873
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The minor groove covalent reactive drugs anthramycin and (+)-CC-1065 and their interstrand cross-linking derivatives.
    Hurley LH
    IARC Sci Publ; 1994; (125):295-312. PubMed ID: 7806319
    [No Abstract]   [Full Text] [Related]  

  • 14. Effects of U-71,184 and several other CC-1065 analogues on cell survival and cell cycle of Chinese hamster ovary cells.
    Adams EG; Badiner GJ; Bhuyan BK
    Cancer Res; 1988 Jan; 48(1):109-16. PubMed ID: 2446739
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Solution structure of the calicheamicin gamma 1I-DNA complex.
    Kumar RA; Ikemoto N; Patel DJ
    J Mol Biol; 1997 Jan; 265(2):187-201. PubMed ID: 9020982
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CC-1065 (NSC 298223), a novel antitumor agent that interacts strongly with double-stranded DNA.
    Li LH; Swenson DH; Schpok SL; Kuentzel SL; Dayton BD; Krueger WC
    Cancer Res; 1982 Mar; 42(3):999-1004. PubMed ID: 6174220
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Calf thymus DNA binding/bonding properties of CC-1065 and analogs as related to their biological activities and toxicities.
    Krueger WC; Prairie MD
    Chem Biol Interact; 1992 Mar; 82(1):31-46. PubMed ID: 1312395
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A model for the T-antigen-induced structural alteration of the SV40 replication origin based upon experiments with specific probes for bent, straight, and unwound DNA.
    Han FX; Hurley LH
    Biochemistry; 1996 Jun; 35(24):7993-8001. PubMed ID: 8672503
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Manipulative interplay of two adozelesin molecules with d(ATTAAT)â‚‚achieving ligand-stacked Watson-Crick and Hoogsteen base-paired duplex adducts.
    Hopton SR; Thompson AS
    Biochemistry; 2011 May; 50(19):4143-54. PubMed ID: 21469674
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence for a common molecular basis for sequence recognition of N3-guanine and N3-adenine DNA adducts involving the covalent bonding reaction of (+)-CC-1065.
    Park HJ
    Arch Pharm Res; 2002 Feb; 25(1):11-24. PubMed ID: 11885687
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.