These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

170 related articles for article (PubMed ID: 1543525)

  • 21. Molecular basis for sequence selective DNA alkylation by (+)- and ent-(-)-CC-1065 and related agents: alkylation site models that accommodate the offset AT-rich adenine N3 alkylation selectivity.
    Boger DL; Johnson DS; Yun W; Tarby CM
    Bioorg Med Chem; 1994 Feb; 2(2):115-35. PubMed ID: 7922122
    [TBL] [Abstract][Full Text] [Related]  

  • 22. DNA sequence recognition by the antitumor antibiotic CC-1065 and analogs of CC-1065.
    Krueger WC; Hatzenbuhler NT; Prairie MD; Shea MH
    Chem Biol Interact; 1991; 79(3):265-86. PubMed ID: 1913973
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Solution conformation of the (-)-trans-anti-[BP]dG adduct opposite a deletion site in a DNA duplex: intercalation of the covalently attached benzo[a]pyrene into the helix with base displacement of the modified deoxyguanosine into the minor groove.
    Feng B; Gorin A; Kolbanovskiy A; Hingerty BE; Geacintov NE; Broyde S; Patel DJ
    Biochemistry; 1997 Nov; 36(45):13780-90. PubMed ID: 9374854
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis, cytotoxicity and antitumor activity of some new simplified pyrazole analogs of the antitumor agent CC-1065. Effect of an hydrophobic group on antitumor activity.
    Baraldi PG; Cacciari B; Guiotto A; Romagnoli R; Spalluto G; Zaid AN; Cozzi P; Geroni C; Mongelli N
    Farmaco; 1997 Dec; 52(12):711-6. PubMed ID: 9648274
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Recognition and repair of the CC-1065-(N3-adenine)-DNA adduct by the UVRABC nucleases.
    Tang MS; Lee CS; Doisy R; Ross L; Needham-VanDevanter DR; Hurley LH
    Biochemistry; 1988 Feb; 27(3):893-901. PubMed ID: 2966637
    [TBL] [Abstract][Full Text] [Related]  

  • 26. (+)-CC-1065 as a structural probe of Mu transposase-induced bending of DNA: overcoming limitations of hydroxyl-radical footprinting.
    Ding ZM; Harshey RM; Hurley LH
    Nucleic Acids Res; 1993 Sep; 21(18):4281-7. PubMed ID: 8414983
    [TBL] [Abstract][Full Text] [Related]  

  • 27. A-tract and (+)-CC-1065-induced bending of DNA. Comparison of structural features using non-denaturing gel analysis, hydroxyl-radical footprinting, and high-field NMR.
    Sun D; Lin CH; Hurley LH
    Biochemistry; 1993 May; 32(17):4487-95. PubMed ID: 8387334
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A noncovalent binding-translocation mechanism for site-specific CC-1065-DNA recognition.
    Gunz D; Naegeli H
    Biochem Pharmacol; 1996 Aug; 52(3):447-53. PubMed ID: 8687499
    [TBL] [Abstract][Full Text] [Related]  

  • 29. CC-1065 CBI analogs: an example of enhancement of DNA alkylation efficiency through introduction of stabilizing electrostatic interactions.
    Boger DL; Yun W; Han N; Johnson DS
    Bioorg Med Chem; 1995 Jun; 3(6):611-21. PubMed ID: 7582940
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Interaction of CC-1065 and its analogues with mouse DNA and chromatin.
    Moy BC; Prairie MD; Krueger WC; Bhuyan BK
    Cancer Res; 1989 Apr; 49(8):1983-8. PubMed ID: 2702639
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Determination of the major tautomeric form of the covalently modified adenine in the (+)-CC-1065-DNA adduct by 1H and 15N NMR studies.
    Lin CH; Hurley LH
    Biochemistry; 1990 Oct; 29(41):9503-7. PubMed ID: 2271598
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Molecular basis for sequence-specific DNA alkylation by CC-1065.
    Hurley LH; Lee CS; McGovren JP; Warpehoski MA; Mitchell MA; Kelly RC; Aristoff PA
    Biochemistry; 1988 May; 27(10):3886-92. PubMed ID: 3408734
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structure of the (+)-CC-1065-DNA adduct: critical role of ordered water molecules and implications for involvement of phosphate catalysis in the covalent reaction.
    Lin CH; Beale JM; Hurley LH
    Biochemistry; 1991 Apr; 30(15):3597-602. PubMed ID: 2015216
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inhibition of human DNA ligase by anthracyclines and distamycins.
    Ciarrocchi G; Fontana M; Spadari S; Montecucco A
    Anticancer Res; 1991; 11(3):1317-22. PubMed ID: 1888166
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Construction and characterization of a site-directed CC-1065-N3-adenine adduct within a 117 base pair DNA restriction fragment.
    Needham-VanDevanter DR; Hurley LH
    Biochemistry; 1986 Dec; 25(26):8430-6. PubMed ID: 3030397
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis and biochemical evaluation of the CBI-PDE-I-dimer, a benzannelated analog of (+)-CC-1065 that also produces delayed toxicity in mice.
    Aristoff PA; Johnson PD; Sun D; Hurley LH
    J Med Chem; 1993 Jul; 36(14):1956-63. PubMed ID: 8336335
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Solution structure of the (+)-cis-anti-benzo[a]pyrene-dA ([BP]dA) adduct opposite dT in a DNA duplex.
    Mao B; Gu Z; Gorin A; Chen J; Hingerty BE; Amin S; Broyde S; Geacintov NE; Patel DJ
    Biochemistry; 1999 Aug; 38(33):10831-42. PubMed ID: 10451380
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Demonstration of a pronounced effect of noncovalent binding selectivity on the (+)-CC-1065 DNA alkylation and identification of the pharmacophore of the alkylation subunit.
    Boger DL; Zarrinmayeh H; Munk SA; Kitos PA; Suntornwat O
    Proc Natl Acad Sci U S A; 1991 Feb; 88(4):1431-5. PubMed ID: 1847523
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A demonstration of the intrinsic importance of stabilizing hydrophobic binding and non-covalent van der Waals contacts dominant in the non-covalent CC-1065/B-DNA binding.
    Boger DL; Invergo BJ; Coleman RS; Zarrinmayeh H; Kitos PA; Thompson SC; Leong T; McLaughlin LW
    Chem Biol Interact; 1990; 73(1):29-52. PubMed ID: 2406033
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Mutagenicity of the antitumor antibiotic CC-1065 and its analogues in mammalian (V79) cells and bacteria.
    Harbach PR; Zimmer DM; Mazurek JH; Bhuyan BK
    Cancer Res; 1988 Jan; 48(1):32-6. PubMed ID: 3334998
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.