91 related articles for article (PubMed ID: 15450176)
1. Dihydropyrimidine dehydrogenase: a flavoprotein with four iron-sulfur clusters.
Schnackerz KD; Dobritzsch D; Lindqvist Y; Cook PF
Biochim Biophys Acta; 2004 Sep; 1701(1-2):61-74. PubMed ID: 15450176
[TBL] [Abstract][Full Text] [Related]
2. Porcine recombinant dihydropyrimidine dehydrogenase: comparison of the spectroscopic and catalytic properties of the wild-type and C671A mutant enzymes.
Rosenbaum K; Jahnke K; Curti B; Hagen WR; Schnackerz KD; Vanoni MA
Biochemistry; 1998 Dec; 37(50):17598-609. PubMed ID: 9860876
[TBL] [Abstract][Full Text] [Related]
3. Mammalian dihydropyrimidine dehydrogenase: Added mechanistic details from transient-state analysis of charge transfer complexes.
Smith MM; Forouzesh DC; Kaley NE; Liu D; Moran GR
Arch Biochem Biophys; 2023 Mar; 736():109517. PubMed ID: 36681231
[TBL] [Abstract][Full Text] [Related]
4. Insights into the mechanism of dihydropyrimidine dehydrogenase from site-directed mutagenesis targeting the active site loop and redox cofactor coordination.
Lohkamp B; Voevodskaya N; Lindqvist Y; Dobritzsch D
Biochim Biophys Acta; 2010 Dec; 1804(12):2198-206. PubMed ID: 20831907
[TBL] [Abstract][Full Text] [Related]
5. Perturbing the Movement of Hydrogens to Delineate and Assign Events in the Reductive Activation and Turnover of Porcine Dihydropyrimidine Dehydrogenase.
Beaupre BA; Forouzesh DC; Butrin A; Liu D; Moran GR
Biochemistry; 2021 Jun; 60(22):1764-1775. PubMed ID: 34032117
[TBL] [Abstract][Full Text] [Related]
6. Mammalian dihydropyrimidine dehydrogenase.
Forouzesh DC; Moran GR
Arch Biochem Biophys; 2021 Dec; 714():109066. PubMed ID: 34717904
[TBL] [Abstract][Full Text] [Related]
7. Overexpression and characterization of Escherichia coli dihydropyrimidine dehydrogenase: a four iron-sulphur cluster containing flavoprotein.
Yoshioka H; Ishida T; Mihara H
J Biochem; 2021 Dec; 170(4):511-520. PubMed ID: 34097066
[TBL] [Abstract][Full Text] [Related]
8. Transient-State Analysis of Porcine Dihydropyrimidine Dehydrogenase Reveals Reductive Activation by NADPH.
Beaupre BA; Forouzesh DC; Moran GR
Biochemistry; 2020 Jul; 59(26):2419-2431. PubMed ID: 32516529
[TBL] [Abstract][Full Text] [Related]
9. The unexpected structural role of glutamate synthase [4Fe-4S](+1,+2) clusters as demonstrated by site-directed mutagenesis of conserved C residues at the N-terminus of the enzyme beta subunit.
Agnelli P; Dossena L; Colombi P; Mulazzi S; Morandi P; Tedeschi G; Negri A; Curti B; Vanoni MA
Arch Biochem Biophys; 2005 Apr; 436(2):355-66. PubMed ID: 15797248
[TBL] [Abstract][Full Text] [Related]
10. The unusual chemical sequences of mammalian dihydropyrimidine dehydrogenase revealed by transient-state analysis.
Smith MM; Moran GR
Methods Enzymol; 2023; 685():373-403. PubMed ID: 37245908
[TBL] [Abstract][Full Text] [Related]
11. Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer.
Dobritzsch D; Ricagno S; Schneider G; Schnackerz KD; Lindqvist Y
J Biol Chem; 2002 Apr; 277(15):13155-66. PubMed ID: 11796730
[TBL] [Abstract][Full Text] [Related]
12. Electron transfer in flavocytochrome P450 BM3: kinetics of flavin reduction and oxidation, the role of cysteine 999, and relationships with mammalian cytochrome P450 reductase.
Roitel O; Scrutton NS; Munro AW
Biochemistry; 2003 Sep; 42(36):10809-21. PubMed ID: 12962506
[TBL] [Abstract][Full Text] [Related]
13. Dihydropyrmidine dehydrogenase from Escherichia coli: Transient state analysis reveals both reductive activation prior to turnover and diminished substrate effector roles relative to the mammalian form.
Alt TB; Hoag MR; Moran GR
Arch Biochem Biophys; 2023 Oct; 748():109772. PubMed ID: 37820757
[TBL] [Abstract][Full Text] [Related]
14. Flavin reductase P: structure of a dimeric enzyme that reduces flavin.
Tanner JJ; Lei B; Tu SC; Krause KL
Biochemistry; 1996 Oct; 35(42):13531-9. PubMed ID: 8885832
[TBL] [Abstract][Full Text] [Related]
15. Purification and characterization of dihydropyrimidine dehydrogenase from Alcaligenes eutrophus.
Schmitt U; Jahnke K; Rosenbaum K; Cook PF; Schnackerz KD
Arch Biochem Biophys; 1996 Aug; 332(1):175-82. PubMed ID: 8806723
[TBL] [Abstract][Full Text] [Related]
16. A hydrogen bond network in the active site of Anabaena ferredoxin-NADP(+) reductase modulates its catalytic efficiency.
Sánchez-Azqueta A; Herguedas B; Hurtado-Guerrero R; Hervás M; Navarro JA; Martínez-Júlvez M; Medina M
Biochim Biophys Acta; 2014 Feb; 1837(2):251-63. PubMed ID: 24200908
[TBL] [Abstract][Full Text] [Related]
17. Secondary tritium and solvent deuterium isotope effects as a probe of the reaction catalyzed by porcine recombinant dihydropyrimidine dehydrogenase.
Rosenbaum K; Jahnke K; Schnackerz KD; Cook PF
Biochemistry; 1998 Jun; 37(25):9156-9. PubMed ID: 9636062
[TBL] [Abstract][Full Text] [Related]
18. A ferredoxin-dependent dihydropyrimidine dehydrogenase in Clostridium chromiireducens.
Wang F; Wei Y; Lu Q; Ang EL; Zhao H; Zhang Y
Biosci Rep; 2020 Jul; 40(7):. PubMed ID: 32614053
[TBL] [Abstract][Full Text] [Related]
19. Equilibrium and transient state spectrophotometric studies of the mechanism of reduction of the flavoprotein domain of P450BM-3.
Sevrioukova I; Shaffer C; Ballou DP; Peterson JA
Biochemistry; 1996 Jun; 35(22):7058-68. PubMed ID: 8679531
[TBL] [Abstract][Full Text] [Related]
20. Purification, characterization, and kinetics of porcine recombinant dihydropyrimidine dehydrogenase.
Rosenbaum K; Schaffrath B; Hagen WR; Jahnke K; Gonzalez FJ; Cook PF; Schnackerz KD
Protein Expr Purif; 1997 Jul; 10(2):185-91. PubMed ID: 9226714
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]