BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

166 related articles for article (PubMed ID: 15451030)

  • 1. Lyn contributes to regulation of multiple Kit-dependent signaling pathways in murine bone marrow mast cells.
    Shivakrupa R; Linnekin D
    Cell Signal; 2005 Jan; 17(1):103-9. PubMed ID: 15451030
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Fyn kinase acts upstream of Shp2 and p38 mitogen-activated protein kinase to promote chemotaxis of mast cells towards stem cell factor.
    Samayawardhena LA; Hu J; Stein PL; Craig AW
    Cell Signal; 2006 Sep; 18(9):1447-54. PubMed ID: 16442778
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Src kinase Lyn is a negative regulator of mast cell proliferation.
    Hernandez-Hansen V; Mackay GA; Lowell CA; Wilson BS; Oliver JM
    J Leukoc Biol; 2004 Jan; 75(1):143-51. PubMed ID: 14525964
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Kit signaling through PI 3-kinase and Src kinase pathways: an essential role for Rac1 and JNK activation in mast cell proliferation.
    Timokhina I; Kissel H; Stella G; Besmer P
    EMBO J; 1998 Nov; 17(21):6250-62. PubMed ID: 9799234
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stem cell factor augments Fc epsilon RI-mediated TNF-alpha production and stimulates MAP kinases via a different pathway in MC/9 mast cells.
    Ishizuka T; Kawasome H; Terada N; Takeda K; Gerwins P; Keller GM; Johnson GL; Gelfand EW
    J Immunol; 1998 Oct; 161(7):3624-30. PubMed ID: 9759885
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The early growth response factor-1 contributes to interleukin-13 production by mast cells in response to stem cell factor stimulation.
    Li B; Berman J; Wu P; Liu F; Tang JT; Lin TJ
    J Immunotoxicol; 2008 Apr; 5(2):163-71. PubMed ID: 18569387
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lck associates with and is activated by Kit in a small cell lung cancer cell line: inhibition of SCF-mediated growth by the Src family kinase inhibitor PP1.
    Krystal GW; DeBerry CS; Linnekin D; Litz J
    Cancer Res; 1998 Oct; 58(20):4660-6. PubMed ID: 9788619
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Early myeloid cells expressing c-KIT isoforms differ in signal transduction, survival and chemotactic responses to Stem Cell Factor.
    Young SM; Cambareri AC; Odell A; Geary SM; Ashman LK
    Cell Signal; 2007 Dec; 19(12):2572-81. PubMed ID: 17855052
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stromal cell-derived factor-1 alpha and stem cell factor/kit ligand share signaling pathways in hemopoietic progenitors: a potential mechanism for cooperative induction of chemotaxis.
    Dutt P; Wang JF; Groopman JE
    J Immunol; 1998 Oct; 161(7):3652-8. PubMed ID: 9759889
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel signaling pathway associated with Lyn, PI 3-kinase and Akt supports the proliferation of myeloma cells.
    Iqbal MS; Tsuyama N; Obata M; Ishikawa H
    Biochem Biophys Res Commun; 2010 Feb; 392(3):415-20. PubMed ID: 20079716
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Impaired tyrosine phosphorylation and Ca2+ mobilization, but not degranulation, in lyn-deficient bone marrow-derived mast cells.
    Nishizumi H; Yamamoto T
    J Immunol; 1997 Mar; 158(5):2350-5. PubMed ID: 9036984
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lyn is required for normal stem cell factor-induced proliferation and chemotaxis of primary hematopoietic cells.
    O'Laughlin-Bunner B; Radosevic N; Taylor ML; Shivakrupa ; DeBerry C; Metcalfe DD; Zhou M; Lowell C; Linnekin D
    Blood; 2001 Jul; 98(2):343-50. PubMed ID: 11435302
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The PH domain adaptor protein Bam32/DAPP1 functions in mast cells to restrain FcɛRI-induced calcium flux and granule release.
    Hou S; Pauls SD; Liu P; Marshall AJ
    Mol Immunol; 2010; 48(1-3):89-97. PubMed ID: 20956018
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta.
    Song JS; Swann PG; Szallasi Z; Blank U; Blumberg PM; Rivera J
    Oncogene; 1998 Jul; 16(26):3357-68. PubMed ID: 9692543
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Balanced interactions between Lyn, the p85alpha regulatory subunit of class I(A) phosphatidylinositol-3-kinase, and SHIP are essential for mast cell growth and maturation.
    Ma P; Vemula S; Munugalavadla V; Chen J; Sims E; Borneo J; Kondo T; Ramdas B; Mali RS; Li S; Hashino E; Takemoto C; Kapur R
    Mol Cell Biol; 2011 Oct; 31(19):4052-62. PubMed ID: 21791602
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of MAP kinases, pp90rsk and pp70-S6 kinases in mouse mast cells by signaling through the c-kit receptor tyrosine kinase or Fc epsilon RI: rapamycin inhibits activation of pp70-S6 kinase and proliferation in mouse mast cells.
    Tsai M; Chen RH; Tam SY; Blenis J; Galli SJ
    Eur J Immunol; 1993 Dec; 23(12):3286-91. PubMed ID: 7504992
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Positive and negative regulation of Fc epsilon receptor I-mediated signaling events by Lyn kinase C-terminal tyrosine phosphorylation.
    Tolar P; Dráberová L; Tolarová H; Dráber P
    Eur J Immunol; 2004 Apr; 34(4):1136-45. PubMed ID: 15048725
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparative analysis of signaling pathways between mast cell growth factor (c-kit ligand) and granulocyte-macrophage colony-stimulating factor in a human factor-dependent myeloid cell line involves phosphorylation of Raf-1, GTPase-activating protein and mitogen-activated protein kinase.
    Miyazawa K; Hendrie PC; Mantel C; Wood K; Ashman LK; Broxmeyer HE
    Exp Hematol; 1991 Dec; 19(11):1110-23. PubMed ID: 1721591
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Increased megakaryocytopoiesis in Lyn-deficient mice.
    Lannutti BJ; Minear J; Blake N; Drachman JG
    Oncogene; 2006 Jun; 25(23):3316-24. PubMed ID: 16418722
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RabGEF1 regulates stem cell factor/c-Kit-mediated signaling events and biological responses in mast cells.
    Kalesnikoff J; Rios EJ; Chen CC; Nakae S; Zabel BA; Butcher EC; Tsai M; Tam SY; Galli SJ
    Proc Natl Acad Sci U S A; 2006 Feb; 103(8):2659-64. PubMed ID: 16533754
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.