These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

214 related articles for article (PubMed ID: 15454230)

  • 1. Camptothecin analogs with bulky, hydrophobic substituents at the 7-position via a Grignard reaction.
    Manikumar G; Wadkins RM; Bearss D; Von Hoff DD; Wani MC; Wall ME
    Bioorg Med Chem Lett; 2004 Nov; 14(21):5377-81. PubMed ID: 15454230
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis of new camptothecin analogs with improved antitumor activities.
    Niizuma S; Tsukazaki M; Suda H; Murata T; Ohwada J; Ozawa S; Fukuda H; Murasaki C; Kohchi M; Morikami K; Yoshinari K; Endo M; Ura M; Tanimura H; Miyazaki Y; Takasuka T; Kawashima A; Nanba E; Nakano K; Ogawa K; Kobayashi K; Okabe H; Umeda I; Shimma N
    Bioorg Med Chem Lett; 2009 Apr; 19(7):2018-21. PubMed ID: 19254843
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Design, synthesis, and biological evaluation of cytotoxic 11-alkenylindenoisoquinoline topoisomerase I inhibitors and indenoisoquinoline-camptothecin hybrids.
    Fox BM; Xiao X; Antony S; Kohlhagen G; Pommier Y; Staker BL; Stewart L; Cushman M
    J Med Chem; 2003 Jul; 46(15):3275-82. PubMed ID: 12852757
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and antitumor activity of the hexacyclic camptothecin derivatives.
    Gao H; Zhang X; Chen Y; Shen H; Pang T; Sun J; Xu C; Ding J; Li C; Lu W
    Bioorg Med Chem Lett; 2005 Jul; 15(13):3233-6. PubMed ID: 15913996
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and antitumor activity of aromatic camptothecin esters.
    Cao Z; Mendoza J; Dejesus A; Vardeman D; Giovanella B
    Int J Mol Med; 2008 Apr; 21(4):477-87. PubMed ID: 18360694
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of 10,11-methylenedioxy-14-azacamptothecin.
    Elban MA; Sun W; Eisenhauer BM; Gao R; Hecht SM
    Org Lett; 2006 Aug; 8(16):3513-6. PubMed ID: 16869648
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and cytotoxic activity of substituted 7-aryliminomethyl derivatives of camptothecin.
    Dallavalle S; Merlini L; Morini G; Musso L; Penco S; Beretta GL; Tinelli S; Zunino F
    Eur J Med Chem; 2004 Jun; 39(6):507-13. PubMed ID: 15183909
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Homocamptothecins: synthesis and antitumor activity of novel E-ring-modified camptothecin analogues.
    Lavergne O; Lesueur-Ginot L; Pla Rodas F; Kasprzyk PG; Pommier J; Demarquay D; Prévost G; Ulibarri G; Rolland A; Schiano-Liberatore AM; Harnett J; Pons D; Camara J; Bigg DC
    J Med Chem; 1998 Dec; 41(27):5410-9. PubMed ID: 9876111
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of nitrated indenoisoquinolines as topoisomerase I inhibitors.
    Morrell A; Antony S; Kohlhagen G; Pommier Y; Cushman M
    Bioorg Med Chem Lett; 2004 Jul; 14(14):3659-63. PubMed ID: 15203138
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Camptothecin: current perspectives.
    Thomas CJ; Rahier NJ; Hecht SM
    Bioorg Med Chem; 2004 Apr; 12(7):1585-604. PubMed ID: 15028252
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis of 14-azacamptothecin, a water-soluble topoisomerase I poison.
    Rahier NJ; Cheng K; Gao R; Eisenhauer BM; Hecht SM
    Org Lett; 2005 Mar; 7(5):835-7. PubMed ID: 15727453
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and antitumor activity of novel 20s-camptothecin analogues.
    Li Q; Lv H; Zu Y; Qu Z; Yao L; Su L; Liu C; Wang L
    Bioorg Med Chem Lett; 2009 Jan; 19(2):513-5. PubMed ID: 19056266
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Total and semisynthesis and in vitro studies of both enantiomers of 20-fluorocamptothecin.
    Tangirala RS; Dixon R; Yang D; Ambrus A; Antony S; Agama K; Pommier Y; Curran DP
    Bioorg Med Chem Lett; 2005 Nov; 15(21):4736-40. PubMed ID: 16140529
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thiocamptothecin.
    Samorì C; Guerrini A; Varchi G; Zunino F; Beretta GL; Femoni C; Bombardelli E; Fontana G; Battaglia A
    J Med Chem; 2008 May; 51(10):3040-4. PubMed ID: 18419110
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis and preliminary bioevaluation of novel E-ring modified acetal analog of camptothecin as cytotoxic agents.
    Zhu L; Zhuang C; Lei N; Guo Z; Sheng C; Dong G; Wang S; Zhang Y; Yao J; Miao Z; Zhang W
    Eur J Med Chem; 2012 Oct; 56():1-9. PubMed ID: 23084702
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Novel autoxidative cleavage reaction of 9-fluoredenes discovered during synthesis of a potential DNA-threading indenoisoquinoline.
    Xiao X; Antony S; Kohlhagen G; Pommier Y; Cushman M
    J Org Chem; 2004 Oct; 69(22):7495-501. PubMed ID: 15497974
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and antitumor activity of ring A- and F-modified hexacyclic camptothecin analogues.
    Sugimori M; Ejima A; Ohsuki S; Uoto K; Mitsui I; Kawato Y; Hirota Y; Sato K; Terasawa H
    J Med Chem; 1998 Jun; 41(13):2308-18. PubMed ID: 9632364
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and cytotoxic activity of new 9-substituted camptothecins.
    Dallavalle S; Rocchetta DG; Musso L; Merlini L; Morini G; Penco S; Tinelli S; Beretta GL; Zunino F
    Bioorg Med Chem Lett; 2008 May; 18(9):2781-7. PubMed ID: 18434153
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural modification of 3-arylisoquinolines to isoindolo[2,1-b]isoquinolinones for the development of novel topoisomerase 1 inhibitors with molecular docking study.
    Van HT; Cho WJ
    Bioorg Med Chem Lett; 2009 May; 19(9):2551-4. PubMed ID: 19328687
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Water soluble inhibitors of topoisomerase I: quaternary salt derivatives of camptothecin.
    Lackey K; Sternbach DD; Croom DK; Emerson DL; Evans MG; Leitner PL; Luzzio MJ; McIntyre G; Vuong A; Yates J; Besterman JM
    J Med Chem; 1996 Feb; 39(3):713-9. PubMed ID: 8576914
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.