91 related articles for article (PubMed ID: 15456257)
1. Antitumor agents. 234. Design, synthesis, and biological evaluation of novel 4beta-[(4' '-benzamido)-amino]-4'-o-demethyl-epipodophyllotoxin derivatives.
Xiao Z; Bastow KF; Vance JR; Sidwell RS; Wang HK; Chen MS; Shi Q; Lee KH
J Med Chem; 2004 Oct; 47(21):5140-8. PubMed ID: 15456257
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and cytotoxic activity on human cancer cells of carbamate derivatives of 4β-(1,2,3-triazol-1-yl)podophyllotoxin.
Liu JF; Sang CY; Xu XH; Zhang LL; Yang X; Hui L; Zhang JB; Chen SW
Eur J Med Chem; 2013 Jun; 64():621-8. PubMed ID: 23711769
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and biological evaluation of novel podophyllotoxin analogs as antitumor agents.
Zhang ZH; Zhang LM; Luo G; Zhang S; Chen H; Zhou J
J Asian Nat Prod Res; 2014; 16(5):527-34. PubMed ID: 24824554
[TBL] [Abstract][Full Text] [Related]
4. Adva-27a, a novel podophyllotoxin derivative found to be effective against multidrug resistant human cancer cells.
Merzouki A; Buschmann MD; Jean M; Young RS; Liao S; Gal S; Li Z; Slilaty SN
Anticancer Res; 2012 Oct; 32(10):4423-32. PubMed ID: 23060568
[TBL] [Abstract][Full Text] [Related]
5. 4β-[4'-(1-(Aryl)ureido)benzamide]podophyllotoxins as DNA topoisomerase I and IIα inhibitors and apoptosis inducing agents.
Kamal A; Suresh P; Ramaiah MJ; Srinivasa Reddy T; Kapavarapu RK; Rao BN; Imthiajali S; Lakshminarayan Reddy T; Pushpavalli SN; Shankaraiah N; Pal-Bhadra M
Bioorg Med Chem; 2013 Sep; 21(17):5198-208. PubMed ID: 23849207
[TBL] [Abstract][Full Text] [Related]
6. Design, synthesis and potent cytotoxic activity of novel podophyllotoxin derivatives.
Li WQ; Wang XL; Qian K; Liu YQ; Wang CY; Yang L; Tian J; Morris-Natschke SL; Zhou XW; Lee KH
Bioorg Med Chem; 2013 Apr; 21(8):2363-2369. PubMed ID: 23490151
[TBL] [Abstract][Full Text] [Related]
7. Design, synthesis, and antitumor activity of novel podophyllotoxin derivatives as potent anticancer agents.
Liu J; Cao B; Gao Y; Bai M; Mei X; Chen H; Jiang YG; Huang DJ
J Asian Nat Prod Res; 2013 Sep; 15(9):985-92. PubMed ID: 23859462
[TBL] [Abstract][Full Text] [Related]
8. A rational design strategy of the novel topoisomerase II inhibitors for the synthesis of the 4-O-(2-pyrazinecarboxylic)-4'-demethylepipodophyllotoxin with antitumor activity by diminishing the relaxation reaction of topoisomerase II-DNA decatenation.
Zhao W; Chen L; Li HM; Wang DJ; Li DS; Chen T; Yuan ZP; Tang YJ
Bioorg Med Chem; 2014 Jun; 22(11):2998-3007. PubMed ID: 24775914
[TBL] [Abstract][Full Text] [Related]
9. Semi-synthesis and biological evaluation of 1,2,3-triazole-based podophyllotoxin congeners as potent antitumor agents inducing apoptosis in HepG2 cells.
Chen J; Ma L; Zhang R; Tang J; Lai H; Wang J; Wang G; Xu Q; Chen T; Peng F; Qiu J; Liang X; Cao D; Ran Y; Peng A; Wei Y; Chen L
Arch Pharm (Weinheim); 2012 Dec; 345(12):945-56. PubMed ID: 22949330
[TBL] [Abstract][Full Text] [Related]
10. Identification of Novel 4'-
Xi W; Sun H; Bastow KF; Xiao Z; Lee KH
Molecules; 2022 Aug; 27(15):. PubMed ID: 35956979
[TBL] [Abstract][Full Text] [Related]
11. Structure-based design, synthesis and biological testing of piperazine-linked bis-epipodophyllotoxin etoposide analogs.
Yadav AA; Chee GL; Wu X; Patel D; Yalowich JC; Hasinoff BB
Bioorg Med Chem; 2015 Jul; 23(13):3542-51. PubMed ID: 25922181
[TBL] [Abstract][Full Text] [Related]
12. Design and synthesis of the novel DNA topoisomerase II inhibitors: esterification and amination substituted 4'-demethylepipodophyllotoxin derivates exhibiting anti-tumor activity by activating ATM/ATR signaling pathways.
Xiao L; Zhao W; Li HM; Wan DJ; Li DS; Chen T; Tang YJ
Eur J Med Chem; 2014 Jun; 80():267-77. PubMed ID: 24793877
[TBL] [Abstract][Full Text] [Related]
13. A convergent synthesis of alkyne-azide cycloaddition derivatives of 4-α,β-2-propyne podophyllotoxin depicting potent cytotoxic activity.
Zilla MK; Nayak D; Vishwakarma RA; Sharma PR; Goswami A; Ali A
Eur J Med Chem; 2014 Apr; 77():47-55. PubMed ID: 24607588
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, cytotoxicity and topoisomerase II inhibitory activity of lomefloxacin derivatives.
Zhou Y; Xu X; Sun Y; Wang H; Sun H; You Q
Bioorg Med Chem Lett; 2013 May; 23(10):2974-8. PubMed ID: 23566520
[TBL] [Abstract][Full Text] [Related]
15. Toward synthesis of third-generation spin-labeled podophyllotoxin derivatives using isocyanide multicomponent reactions.
Kou L; Wang MJ; Wang LT; Zhao XB; Nan X; Yang L; Liu YQ; Morris-Natschke SL; Lee KH
Eur J Med Chem; 2014 Mar; 75():282-8. PubMed ID: 24553146
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of 4β-(thiazol-2-yl)amino-4'-O-demethyl-4-deoxypodophyllotoxins as topoisomerase-II inhibitors.
Sang CY; Tian HZ; Chen Y; Liu JF; Chen SW; Hui L
Bioorg Med Chem Lett; 2018 Jan; 28(2):71-76. PubMed ID: 29248296
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and evaluation of the cell cycle arrest and CT DNA interaction properties of 4β-amino-4'-O-demethyl-4-deoxypodophyllotoxins.
Liu JF; Sang CY; Qin WW; Zhao J; Hui L; Ding YL; Chen SW
Bioorg Med Chem; 2013 Nov; 21(22):6948-55. PubMed ID: 24095019
[TBL] [Abstract][Full Text] [Related]
18. Antitumor agents 294. Novel E-ring-modified camptothecin-4β-anilino-4'-O-demethyl-epipodophyllotoxin conjugates as DNA topoisomerase I inhibitors and cytotoxic agents.
Ye D; Shi Q; Leung CH; Kim SW; Park SY; Gullen EA; Jiang ZL; Zhu H; Morris-Natschke SL; Cheng YC; Lee KH
Bioorg Med Chem; 2012 Jul; 20(14):4489-94. PubMed ID: 22698783
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and evaluation of novel podophyllotoxin derivatives as potential antitumor agents.
Cheng WH; Cao B; Shang H; Niu C; Zhang LM; Zhang ZH; Tian DL; Zhang S; Chen H; Zou ZM
Eur J Med Chem; 2014 Oct; 85():498-507. PubMed ID: 25113878
[TBL] [Abstract][Full Text] [Related]
20. Recent Advances in the Application of Podophyllotoxin Derivatives to Fight Against Multidrug-Resistant Cancer Cells.
Guo Q; Jiang E
Curr Top Med Chem; 2021; 21(19):1712-1724. PubMed ID: 33441065
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
