BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

335 related articles for article (PubMed ID: 15456269)

  • 21. The novel L- and D-amino acid derivatives of hydroxyurea and hydantoins: synthesis, X-ray crystal structure study, and cytostatic and antiviral activity evaluations.
    Opacić N; Barbarić M; Zorc B; Cetina M; Nagl A; Frković D; Kralj M; Pavelić K; Balzarini J; Andrei G; Snoeck R; De Clercq E; Raić-Malić S; Mintas M
    J Med Chem; 2005 Jan; 48(2):475-82. PubMed ID: 15658861
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Open-chain carbocyclic analogs of adenosine with dihalovinyl unit as potential inhibitors of S-adenosyl-L-homocysteine hydrolase.
    Lewandowska E; Lalama J; Yuan CS; Wnuk SF
    Nucleosides Nucleotides Nucleic Acids; 2003 Sep; 22(9):1747-55. PubMed ID: 14533879
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase.
    Ando T; Iwata M; Zulfiqar F; Miyamoto T; Nakanishi M; Kitade Y
    Bioorg Med Chem; 2008 Apr; 16(7):3809-15. PubMed ID: 18295495
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Synthesis of 5'-branched neplanocin A analogues based on radical-mediated sulfur-extrusive stannylation.
    Kumamoto H; Tanaka H
    Nucleic Acids Symp Ser (Oxf); 2007; (51):145-6. PubMed ID: 18029628
    [TBL] [Abstract][Full Text] [Related]  

  • 25. (Z)- and (E)-[2-Fluoro-2-(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines, a new class of methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity.
    Zhou S; Kern ER; Gullen E; Cheng YC; Drach JC; Matsumi S; Mitsuya H; Zemlicka J
    J Med Chem; 2004 Dec; 47(27):6964-72. PubMed ID: 15615545
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Antitrypanosomal activity of 5'-deoxy-5'-(iodomethylene)adenosine and related 6-N-cyclopropyladenosine analogues.
    Rapp M; Haubrich TA; Perrault J; Mackey ZB; McKerrow JH; Chiang PK; Wnuk SF
    J Med Chem; 2006 Mar; 49(6):2096-102. PubMed ID: 16539398
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Asymmetric synthesis and antiviral activities of L-carbocyclic 2', 3'-didehydro-2',3'-dideoxy and 2',3'-dideoxy nucleosides.
    Wang P; Gullen B; Newton MG; Cheng YC; Schinazi RF; Chu CK
    J Med Chem; 1999 Aug; 42(17):3390-9. PubMed ID: 10464025
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Synthesis of homologated halovinyl derivatives from aristeromycin and their inhibition of human placental S-adenosyl-L-homocysteine hydrolase.
    Wnuk SF; Yuan CS; Borchardt RT; Robins MJ
    Nucleosides Nucleotides; 1998; 17(1-3):99-113. PubMed ID: 9708344
    [TBL] [Abstract][Full Text] [Related]  

  • 29. S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine.
    Shokar A; Au A; An SH; Tong E; Garza G; Zayas J; Wnuk SF; Land KM
    Bioorg Med Chem Lett; 2012 Jun; 22(12):4203-5. PubMed ID: 22579483
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Synthesis and antiviral activity of carbocyclic nucleosides incorporating a modified cyclopentane ring. Part 3: Adenosine and uridine analogues.
    Isabel Nieto M; Manuel Blanco J; Caamaño O; Fernández F; García-Mera X; López C; Balzarini J; De Clercq E
    Nucleosides Nucleotides; 1999 Oct; 18(10):2253-63. PubMed ID: 10616729
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthesis of novel 4'-modified neplanocin A analogues and their inhibitory activity against S-adenosyl-L-l-homocysteine hydrolase.
    Kumamoto H; Deguchi K; Takahashi N; Tanaka H; Kitade Y
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(6-7):733-6. PubMed ID: 18066891
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Sulfur extrusion with tin radical: synthesis of 4',5'-didehydro-5'-deoxy-5'-(tributylstannyl)adenosine, an intermediate for potential inhibitors against S-adenosyl homocysteine hydrolase.
    Kumamoto H; Onuma S; Tanaka H
    J Org Chem; 2004 Jan; 69(1):72-8. PubMed ID: 14703380
    [TBL] [Abstract][Full Text] [Related]  

  • 33. 5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells.
    Cristofoli WA; Wiebe LI; De Clercq E; Andrei G; Snoeck R; Balzarini J; Knaus EE
    J Med Chem; 2007 Jun; 50(12):2851-7. PubMed ID: 17518459
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Inactivation of S-adenosyl-L-homocysteine hydrolase with novel 5'-thioadenosine derivatives. Antiviral effects.
    Guillerm G; Guillerm D; Vandenplas-Vitkowski C; Glapski C; De Clercq E
    Bioorg Med Chem Lett; 2003 May; 13(10):1649-52. PubMed ID: 12729633
    [TBL] [Abstract][Full Text] [Related]  

  • 35. 5-Substituted-2,4-diamino-6-[2-(phosphonomethoxy)ethoxy]pyrimidines-acyclic nucleoside phosphonate analogues with antiviral activity.
    Hocková D; Holý A; Masojídková M; Andrei G; Snoeck R; De Clercq E; Balzarini J
    J Med Chem; 2003 Nov; 46(23):5064-73. PubMed ID: 14584956
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Synthesis, mechanism of action, and antiviral activity of a new series of covalent mechanism-based inhibitors of S-adenosyl-L-homocysteine hydrolase.
    Guillerm G; Guillerm D; Vandenplas-Witkowki C; Rogniaux H; Carte N; Leize E; Van Dorsselaer A; De Clercq E; Lambert C
    J Med Chem; 2001 Aug; 44(17):2743-52. PubMed ID: 11495586
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Synthesis of 4'-modified noraristeromycins to clarify the effect of the 4'-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocysteine hydrolase.
    Ando T; Kojima K; Chahota P; Kozaki A; Milind ND; Kitade Y
    Bioorg Med Chem Lett; 2008 Apr; 18(8):2615-8. PubMed ID: 18374570
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Synthesis and antiviral evaluation of novel 2,3-dihydroxypropyl nucleosides from 2- and 4-thiouracils.
    Abdel-Rahman AA; El-Etrawy AA; Abdel-Megied AE; Zeid IF; El Ashry el SH
    Nucleosides Nucleotides Nucleic Acids; 2008 Dec; 27(12):1257-71. PubMed ID: 19003571
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Unsaturated dideoxy fluoro-ketopyranosyl nucleosides as new cytostatic agents: a convenient synthesis of 2,6-dideoxy-3-fluoro-4-keto-beta-D-glucopyranosyl analogues of uracil, 5-fluorouracil, thymine, N4-benzoyl cytosine and N6-benzoyl adenine.
    Manta S; Tzioumaki N; Tsoukala E; Panagiotopoulou A; Pelecanou M; Balzarini J; Komiotis D
    Eur J Med Chem; 2009 Nov; 44(11):4764-71. PubMed ID: 19595489
    [TBL] [Abstract][Full Text] [Related]  

  • 40. [Synthesis and antiviral evaluation against Vaccinia virus of new N¹-oxide analogues of 5'-noraristeromycin].
    Matiugina ES; Seley-Radtke KL; Andronova VL; Galegov GA; Kochetkov SN; Khandazhinskaia AL
    Bioorg Khim; 2010; 36(6):797-801. PubMed ID: 21317946
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 17.