These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

149 related articles for article (PubMed ID: 15459188)

  • 1. Spermine synthesis is required for normal viability, growth, and fertility in the mouse.
    Wang X; Ikeguchi Y; McCloskey DE; Nelson P; Pegg AE
    J Biol Chem; 2004 Dec; 279(49):51370-5. PubMed ID: 15459188
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Spermine synthase deficiency leads to deafness and a profound sensitivity to alpha-difluoromethylornithine.
    Wang X; Levic S; Gratton MA; Doyle KJ; Yamoah EN; Pegg AE
    J Biol Chem; 2009 Jan; 284(2):930-7. PubMed ID: 19001365
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Use of (Gyro) Gy and spermine synthase transgenic mice to study functions of spermine.
    Wang X; Pegg AE
    Methods Mol Biol; 2011; 720():159-70. PubMed ID: 21318872
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Characterization of transgenic mice with widespread overexpression of spermine synthase.
    Ikeguchi Y; Wang X; McCloskey DE; Coleman CS; Nelson P; Hu G; Shantz LM; Pegg AE
    Biochem J; 2004 Aug; 381(Pt 3):701-7. PubMed ID: 15104536
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Spermine deficiency in Gy mice caused by deletion of the spermine synthase gene.
    Lorenz B; Francis F; Gempel K; Böddrich A; Josten M; Schmahl W; Schmidt J; Lehrach H; Meitinger T; Strom TM
    Hum Mol Genet; 1998 Mar; 7(3):541-7. PubMed ID: 9467015
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Spermine synthase overexpression in vivo does not increase susceptibility to DMBA/TPA skin carcinogenesis or Min-Apc intestinal tumorigenesis.
    Welsh PA; Sass-Kuhn S; Prakashagowda C; McCloskey D; Feith D
    Cancer Biol Ther; 2012 Apr; 13(6):358-68. PubMed ID: 22258329
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Partial deletion of both the spermine synthase gene and the Pex gene in the X-linked hypophosphatemic, gyro (Gy) mouse.
    Meyer RA; Henley CM; Meyer MH; Morgan PL; McDonald AG; Mills C; Price DK
    Genomics; 1998 Mar; 48(3):289-95. PubMed ID: 9545633
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Effect of spermine synthase deficiency on polyamine biosynthesis and content in mice and embryonic fibroblasts, and the sensitivity of fibroblasts to 1,3-bis-(2-chloroethyl)-N-nitrosourea.
    Mackintosh CA; Pegg AE
    Biochem J; 2000 Oct; 351 Pt 2(Pt 2):439-47. PubMed ID: 11023830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Spermine is not essential for survival of Arabidopsis.
    Imai A; Akiyama T; Kato T; Sato S; Tabata S; Yamamoto KT; Takahashi T
    FEBS Lett; 2004 Jan; 556(1-3):148-52. PubMed ID: 14706842
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Skin fibroblasts from spermine synthase-deficient hemizygous gyro male (Gy/Y) mice overproduce spermidine and exhibit increased resistance to oxidative stress but decreased resistance to UV irradiation.
    Nilsson J; Gritli-Linde A; Heby O
    Biochem J; 2000 Dec; 352 Pt 2(Pt 2):381-7. PubMed ID: 11085931
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mouse models to investigate the function of spermine.
    Pegg AE; Wang X
    Commun Integr Biol; 2009 May; 2(3):271-4. PubMed ID: 19641749
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Spermine is not essential for growth of Saccharomyces cerevisiae: identification of the SPE4 gene (spermine synthase) and characterization of a spe4 deletion mutant.
    Hamasaki-Katagiri N; Katagiri Y; Tabor CW; Tabor H
    Gene; 1998 Apr; 210(2):195-201. PubMed ID: 9573363
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Characterization of transgenic mice with overexpression of spermidine synthase.
    Shi C; Welsh PA; Sass-Kuhn S; Wang X; McCloskey DE; Pegg AE; Feith DJ
    Amino Acids; 2012 Feb; 42(2-3):495-505. PubMed ID: 21809077
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Spermine synthase.
    Pegg AE; Michael AJ
    Cell Mol Life Sci; 2010 Jan; 67(1):113-21. PubMed ID: 19859664
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effect of polyamine depletion on caspase activation: a study with spermine synthase-deficient cells.
    Stefanelli C; Pignatti C; Tantini B; Fattori M; Stanic I; Mackintosh CA; Flamigni F; Guarnieri C; Caldarera CM; Pegg AE
    Biochem J; 2001 Apr; 355(Pt 1):199-206. PubMed ID: 11256964
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Modulation of potassium channels in the hearts of transgenic and mutant mice with altered polyamine biosynthesis.
    Lopatin AN; Shantz LM; Mackintosh CA; Nichols CG; Pegg AE
    J Mol Cell Cardiol; 2000 Nov; 32(11):2007-24. PubMed ID: 11040105
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Scots pine aminopropyltransferases shed new light on evolution of the polyamine biosynthesis pathway in seed plants.
    Vuosku J; Karppinen K; Muilu-Mäkelä R; Kusano T; Sagor GHM; Avia K; Alakärppä E; Kestilä J; Suokas M; Nickolov K; Hamberg L; Savolainen O; Häggman H; Sarjala T
    Ann Bot; 2018 May; 121(6):1243-1256. PubMed ID: 29462244
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Spermine deficiency resulting from targeted disruption of the spermine synthase gene in embryonic stem cells leads to enhanced sensitivity to antiproliferative drugs.
    Korhonen VP; Niiranen K; Halmekytö M; Pietilä M; Diegelman P; Parkkinen JJ; Eloranta T; Porter CW; Alhonen L; Jänne J
    Mol Pharmacol; 2001 Feb; 59(2):231-8. PubMed ID: 11160858
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ACAULIS5, an Arabidopsis gene required for stem elongation, encodes a spermine synthase.
    Hanzawa Y; Takahashi T; Michael AJ; Burtin D; Long D; Pineiro M; Coupland G; Komeda Y
    EMBO J; 2000 Aug; 19(16):4248-56. PubMed ID: 10944107
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effects of inhibitors of spermidine and spermine synthesis on polyamine concentrations and growth of transformed mouse fibroblasts.
    Pegg AE; Borchardt RT; Coward JK
    Biochem J; 1981 Jan; 194(1):79-89. PubMed ID: 7305994
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.