These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

118 related articles for article (PubMed ID: 15459249)

  • 21. Modulation of the protein kinase activity of mTOR.
    Lawrence JC; Lin TA; McMahon LP; Choi KM
    Curr Top Microbiol Immunol; 2004; 279():199-213. PubMed ID: 14560959
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Raptor and mTOR: subunits of a nutrient-sensitive complex.
    Kim DH; Sabatini DM
    Curr Top Microbiol Immunol; 2004; 279():259-70. PubMed ID: 14560962
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Ras inhibition in hepatocarcinoma by S-trans-trans-farnesylthiosalicyclic acid: association of its tumor preventive effect with cell proliferation, cell cycle events, and angiogenesis.
    Stärkel P; Charette N; Borbath I; Schneider-Merck T; De Saeger C; Abarca J; Leclercq I; Horsmans Y
    Mol Carcinog; 2012 Oct; 51(10):816-25. PubMed ID: 21882255
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complex.
    Sarbassov DD; Sabatini DM
    J Biol Chem; 2005 Nov; 280(47):39505-9. PubMed ID: 16183647
    [TBL] [Abstract][Full Text] [Related]  

  • 25. The rapamycin-binding domain governs substrate selectivity by the mammalian target of rapamycin.
    McMahon LP; Choi KM; Lin TA; Abraham RT; Lawrence JC
    Mol Cell Biol; 2002 Nov; 22(21):7428-38. PubMed ID: 12370290
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers.
    Zhou X; Tan M; Stone Hawthorne V; Klos KS; Lan KH; Yang Y; Yang W; Smith TL; Shi D; Yu D
    Clin Cancer Res; 2004 Oct; 10(20):6779-88. PubMed ID: 15501954
    [TBL] [Abstract][Full Text] [Related]  

  • 27. LY303511 (2-piperazinyl-8-phenyl-4H-1-benzopyran-4-one) acts via phosphatidylinositol 3-kinase-independent pathways to inhibit cell proliferation via mammalian target of rapamycin (mTOR)- and non-mTOR-dependent mechanisms.
    Kristof AS; Pacheco-Rodriguez G; Schremmer B; Moss J
    J Pharmacol Exp Ther; 2005 Sep; 314(3):1134-43. PubMed ID: 15923340
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.
    Tremblay F; Gagnon A; Veilleux A; Sorisky A; Marette A
    Endocrinology; 2005 Mar; 146(3):1328-37. PubMed ID: 15576463
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibition of the Ras oncoprotein reduces proliferation of hepatocytes in vitro and in vivo in rats.
    da Silva Morais A; Saliez A; Leclercq I; Horsmans Y; Stärkel P
    Clin Sci (Lond); 2008 Jan; 114(1):73-83. PubMed ID: 17678500
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Distinct roles of the mTOR components Rictor and Raptor in MO7e megakaryocytic cells.
    Fuhler GM; Tyl MR; Olthof SG; Lyndsay Drayer A; Blom N; Vellenga E
    Eur J Haematol; 2009 Sep; 83(3):235-45. PubMed ID: 19341427
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Estrogen-induced activation of mammalian target of rapamycin is mediated via tuberin and the small GTPase Ras homologue enriched in brain.
    Yu J; Henske EP
    Cancer Res; 2006 Oct; 66(19):9461-6. PubMed ID: 17018601
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M; Kasprzycka M; Liu X; El-Salem M; Halasa K; Raghunath PN; Bucki R; Wlodarski P; Wasik MA
    Oncogene; 2007 Aug; 26(38):5606-14. PubMed ID: 17353907
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.
    Wlodarski P; Kasprzycka M; Liu X; Marzec M; Robertson ES; Slupianek A; Wasik MA
    Cancer Res; 2005 Sep; 65(17):7800-8. PubMed ID: 16140948
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability.
    Beugnet A; Tee AR; Taylor PM; Proud CG
    Biochem J; 2003 Jun; 372(Pt 2):555-66. PubMed ID: 12611592
    [TBL] [Abstract][Full Text] [Related]  

  • 35. The Ras antagonist S-farnesylthiosalicylic acid induces inhibition of MAPK activation.
    Gana-Weisz M; Haklai R; Marciano D; Egozi Y; Ben-Baruch G; Kloog Y
    Biochem Biophys Res Commun; 1997 Oct; 239(3):900-4. PubMed ID: 9367867
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Mammalian target of rapamycin-dependent phosphorylation of PHAS-I in four (S/T)P sites detected by phospho-specific antibodies.
    Mothe-Satney I; Brunn GJ; McMahon LP; Capaldo CT; Abraham RT; Lawrence JC
    J Biol Chem; 2000 Oct; 275(43):33836-43. PubMed ID: 10942774
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Selective inhibition of Ras-dependent cell growth by farnesylthiosalisylic acid.
    Marom M; Haklai R; Ben-Baruch G; Marciano D; Egozi Y; Kloog Y
    J Biol Chem; 1995 Sep; 270(38):22263-70. PubMed ID: 7673206
    [TBL] [Abstract][Full Text] [Related]  

  • 38. The Ras antagonist, farnesylthiosalicylic acid (FTS), inhibits experimentally-induced liver cirrhosis in rats.
    Reif S; Weis B; Aeed H; Gana-Weis M; Zaidel L; Avni Y; Romanelli RG; Pinzani M; Kloog Y; Bruck R
    J Hepatol; 1999 Dec; 31(6):1053-61. PubMed ID: 10604579
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation.
    Delgoffe GM; Kole TP; Cotter RJ; Powell JD
    Mol Immunol; 2009 Aug; 46(13):2694-8. PubMed ID: 19586661
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Targeting of K-Ras 4B by S-trans,trans-farnesyl thiosalicylic acid.
    Elad G; Paz A; Haklai R; Marciano D; Cox A; Kloog Y
    Biochim Biophys Acta; 1999 Dec; 1452(3):228-42. PubMed ID: 10590312
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 6.