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4. Trypsin: a case study in the structural determinants of enzyme specificity. Hedstrom L Biol Chem; 1996; 377(7-8):465-70. PubMed ID: 8922280 [TBL] [Abstract][Full Text] [Related]
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7. Structural origins of substrate discrimination in trypsin and chymotrypsin. Perona JJ; Hedstrom L; Rutter WJ; Fletterick RJ Biochemistry; 1995 Feb; 34(5):1489-99. PubMed ID: 7849008 [TBL] [Abstract][Full Text] [Related]
8. Converting trypsin to elastase: substitution of the S1 site and adjacent loops reconstitutes esterase specificity but not amidase activity. Hung SH; Hedstrom L Protein Eng; 1998 Aug; 11(8):669-73. PubMed ID: 9749919 [TBL] [Abstract][Full Text] [Related]
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14. Structural consequences of accommodation of four non-cognate amino acid residues in the S1 pocket of bovine trypsin and chymotrypsin. Helland R; Czapinska H; Leiros I; Olufsen M; Otlewski J; Smalås AO J Mol Biol; 2003 Oct; 333(4):845-61. PubMed ID: 14568540 [TBL] [Abstract][Full Text] [Related]
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20. Design of peptide enzymes (pepzymes): surface-simulation synthetic peptides that mimic the chymotrypsin and trypsin active sites exhibit the activity and specificity of the respective enzyme. Atassi MZ; Manshouri T Proc Natl Acad Sci U S A; 1993 Sep; 90(17):8282-6. PubMed ID: 8367494 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]