BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

91 related articles for article (PubMed ID: 15464623)

  • 1. Synthesis and GABA uptake inhibitory properties of 6-aryl iminoxymethyl substituted nipecotic acids.
    N'goka V; Stenbøl TB; Krogsgaard-Larsen P; Schlewer G
    Eur J Med Chem; 2004 Oct; 39(10):889-95. PubMed ID: 15464623
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Syntheses and GABA uptake properties of 6-ether- and 6-enol ether-substituted nipecotic acids.
    N'Goka V; Bissantz C; Bisel P; Stenbøl TB; Krogsgaard-Larsen P; Schlewer G
    Eur J Med Chem; 2004 Jul; 39(7):633-8. PubMed ID: 15236844
    [TBL] [Abstract][Full Text] [Related]  

  • 3. GABA uptake inhibitors containing mono- and diarylmethoxyalkyl N-substituents.
    Falch E; Krogsgaard-Larsen P
    Drug Des Deliv; 1989 May; 4(3):205-15. PubMed ID: 2535204
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis and evaluation of N-substituted nipecotic acid derivatives with an unsymmetrical bis-aromatic residue attached to a vinyl ether spacer as potential GABA uptake inhibitors.
    Quandt G; Höfner G; Wanner KT
    Bioorg Med Chem; 2013 Jun; 21(11):3363-78. PubMed ID: 23598250
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with an alkyne spacer as GABA uptake inhibitors.
    Tóth K; Höfner G; Wanner KT
    Bioorg Med Chem; 2018 Jul; 26(12):3668-3687. PubMed ID: 29886082
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a trans-alkene spacer as potent GABA uptake inhibitors.
    Tóth K; Höfner G; Wanner KT
    Bioorg Med Chem; 2018 Dec; 26(22):5944-5961. PubMed ID: 30442505
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Uptake and release of nipecotic acid by rat brain slices.
    Johnston GA; Stephanson AL; Twitchin B
    J Neurochem; 1976 Jan; 26(1):83-7. PubMed ID: 1255185
    [No Abstract]   [Full Text] [Related]  

  • 8. Design, synthesis, and biological evaluation of the N-diarylalkenyl-piperidinecarboxylic acid derivatives as GABA uptake inhibitors (I).
    Zheng J; Wen R; Luo X; Lin G; Zhang J; Xu L; Guo L; Jiang H
    Bioorg Med Chem Lett; 2006 Jan; 16(1):225-7. PubMed ID: 16246548
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of 4-substituted nipecotic acid derivatives and their evaluation as potential GABA uptake inhibitors.
    Hellenbrand T; Höfner G; Wein T; Wanner KT
    Bioorg Med Chem; 2016 May; 24(9):2072-96. PubMed ID: 27039250
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Stereospecific synthesis and structure-activity relationships of unsymmetrical 4,4-diphenylbut-3-enyl derivatives of nipecotic acid as GAT-1 inhibitors.
    Pizzi DA; Leslie CP; Di Fabio R; Seri C; Bernasconi G; Squaglia M; Carnevale G; Falchi A; Greco E; Mangiarini L; Negri M
    Bioorg Med Chem Lett; 2011 Jan; 21(1):602-5. PubMed ID: 21134748
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Uptake of GABA and nipecotic acid in astrocytes and neurons in primary cultures: changes in the sodium coupling ratio during differentiation.
    Larsson OM; Hertz L; Schousboe A
    J Neurosci Res; 1986; 16(4):699-708. PubMed ID: 3025461
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional GABA uptake at inhibitory synapses in CA1 of chronically epileptic rats.
    Stief F; Piechotta A; Gabriel S; Schmitz D; Draguhn A
    Epilepsy Res; 2005; 66(1-3):199-202. PubMed ID: 16154723
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis of novel GABA uptake inhibitors. Part 6: preparation and evaluation of N-Omega asymmetrically substituted nipecotic acid derivatives.
    Andersen KE; Lau J; Lundt BF; Petersen H; Huusfeldt PO; Suzdak PD; Swedberg MD
    Bioorg Med Chem; 2001 Nov; 9(11):2773-85. PubMed ID: 11597457
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-activity studies on benzhydrol-containing nipecotic acid and guvacine derivatives as potent, orally-active inhibitors of GABA uptake.
    Pavia MR; Lobbestael SJ; Nugiel D; Mayhugh DR; Gregor VE; Taylor CP; Schwarz RD; Brahce L; Vartanian MG
    J Med Chem; 1992 Oct; 35(22):4238-48. PubMed ID: 1433224
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Nipecotic acid: preferential accumulation in the cochlea by GABA uptake systems and selective retrograde transport to brainstem.
    Ryan AF; Schwartz IR
    Brain Res; 1986 Dec; 399(2):399-403. PubMed ID: 3828775
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparison between (RS)-nipecotic acid and GABA transport in cultured astrocytes: coupling with two sodium ions.
    Larsson OM; Schousboe A
    Neurochem Res; 1981 Mar; 6(3):257-66. PubMed ID: 7279105
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of novel GABA uptake inhibitors. 4. Bioisosteric transformation and successive optimization of known GABA uptake inhibitors leading to a series of potent anticonvulsant drug candidates.
    Andersen KE; Sørensen JL; Huusfeldt PO; Knutsen LJ; Lau J; Lundt BF; Petersen H; Suzdak PD; Swedberg MD
    J Med Chem; 1999 Oct; 42(21):4281-91. PubMed ID: 10543872
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Development of Highly Potent GAT1 Inhibitors: Synthesis of Nipecotic Acid Derivatives with N-Arylalkynyl Substituents.
    Lutz T; Wein T; Höfner G; Wanner KT
    ChemMedChem; 2017 Mar; 12(5):362-371. PubMed ID: 28125164
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Entropy as a factor in the binding of gamma-aminobutyric acid and nipecotic acid to the gamma-aminobutyric acid transport system.
    Althaus JS; Martin DL
    Neurochem Res; 1989 Apr; 14(4):311-6. PubMed ID: 2548104
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High-affinity uptake of (RS)-nipecotic acid in astrocytes cultured from mouse brain. Comparison with GABA transport.
    Larsson OM; Krogsgaard-Larsen P; Schousboe A
    J Neurochem; 1980 Apr; 34(4):970-7. PubMed ID: 7359143
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 5.