BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

355 related articles for article (PubMed ID: 15467830)

  • 1. Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.
    Kubota N; Terauchi Y; Tobe K; Yano W; Suzuki R; Ueki K; Takamoto I; Satoh H; Maki T; Kubota T; Moroi M; Okada-Iwabu M; Ezaki O; Nagai R; Ueta Y; Kadowaki T; Noda T
    J Clin Invest; 2004 Oct; 114(7):917-27. PubMed ID: 15467830
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Pdx1 restores beta cell function in Irs2 knockout mice.
    Kushner JA; Ye J; Schubert M; Burks DJ; Dow MA; Flint CL; Dutta S; Wright CV; Montminy MR; White MF
    J Clin Invest; 2002 May; 109(9):1193-201. PubMed ID: 11994408
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Glucokinase and IRS-2 are required for compensatory beta cell hyperplasia in response to high-fat diet-induced insulin resistance.
    Terauchi Y; Takamoto I; Kubota N; Matsui J; Suzuki R; Komeda K; Hara A; Toyoda Y; Miwa I; Aizawa S; Tsutsumi S; Tsubamoto Y; Hashimoto S; Eto K; Nakamura A; Noda M; Tobe K; Aburatani H; Nagai R; Kadowaki T
    J Clin Invest; 2007 Jan; 117(1):246-57. PubMed ID: 17200721
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Subcellular localization of glucose transporter 4 in the hypothalamic arcuate nucleus of ob/ob mice under basal conditions.
    Komori T; Morikawa Y; Tamura S; Doi A; Nanjo K; Senba E
    Brain Res; 2005 Jul; 1049(1):34-42. PubMed ID: 15925330
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dysregulation of insulin receptor substrate 2 in beta cells and brain causes obesity and diabetes.
    Lin X; Taguchi A; Park S; Kushner JA; Li F; Li Y; White MF
    J Clin Invest; 2004 Oct; 114(7):908-16. PubMed ID: 15467829
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Exercise improves glucose homeostasis that has been impaired by a high-fat diet by potentiating pancreatic beta-cell function and mass through IRS2 in diabetic rats.
    Park S; Hong SM; Lee JE; Sung SR
    J Appl Physiol (1985); 2007 Nov; 103(5):1764-71. PubMed ID: 17761790
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chlorpromazine exacerbates hepatic insulin sensitivity via attenuating insulin and leptin signaling pathway, while exercise partially reverses the adverse effects.
    Park S; Hong SM; Lee JE; Sung SR
    Life Sci; 2007 Jun; 80(26):2428-35. PubMed ID: 17512020
    [TBL] [Abstract][Full Text] [Related]  

  • 8. beta-cell-specific deletion of the Igf1 receptor leads to hyperinsulinemia and glucose intolerance but does not alter beta-cell mass.
    Kulkarni RN; Holzenberger M; Shih DQ; Ozcan U; Stoffel M; Magnuson MA; Kahn CR
    Nat Genet; 2002 May; 31(1):111-5. PubMed ID: 11923875
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Analysis of compensatory beta-cell response in mice with combined mutations of Insr and Irs2.
    Kim JJ; Kido Y; Scherer PE; White MF; Accili D
    Am J Physiol Endocrinol Metab; 2007 Jun; 292(6):E1694-701. PubMed ID: 17299086
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of insulin receptor substrate 2 in hypothalamic and beta cell function.
    Choudhury AI; Heffron H; Smith MA; Al-Qassab H; Xu AW; Selman C; Simmgen M; Clements M; Claret M; Maccoll G; Bedford DC; Hisadome K; Diakonov I; Moosajee V; Bell JD; Speakman JR; Batterham RL; Barsh GS; Ashford ML; Withers DJ
    J Clin Invest; 2005 Apr; 115(4):940-50. PubMed ID: 15841180
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Irs-2 coordinates Igf-1 receptor-mediated beta-cell development and peripheral insulin signalling.
    Withers DJ; Burks DJ; Towery HH; Altamuro SL; Flint CL; White MF
    Nat Genet; 1999 Sep; 23(1):32-40. PubMed ID: 10471495
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin secretory defects and impaired islet architecture in pancreatic beta-cell-specific STAT3 knockout mice.
    Gorogawa S; Fujitani Y; Kaneto H; Hazama Y; Watada H; Miyamoto Y; Takeda K; Akira S; Magnuson MA; Yamasaki Y; Kajimoto Y; Hori M
    Biochem Biophys Res Commun; 2004 Jul; 319(4):1159-70. PubMed ID: 15194489
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overexpression of IRS2 in isolated pancreatic islets causes proliferation and protects human beta-cells from hyperglycemia-induced apoptosis.
    Mohanty S; Spinas GA; Maedler K; Zuellig RA; Lehmann R; Donath MY; Trüb T; Niessen M
    Exp Cell Res; 2005 Feb; 303(1):68-78. PubMed ID: 15572028
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Effects of caloric restriction on insulin pathway gene expression in the skeletal muscle and liver of normal and long-lived GHR-KO mice.
    Masternak MM; Al-Regaiey KA; Del Rosario Lim MM; Jimenez-Ortega V; Panici JA; Bonkowski MS; Bartke A
    Exp Gerontol; 2005; 40(8-9):679-84. PubMed ID: 16054319
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Taurine supplementation prevents morpho-physiological alterations in high-fat diet mice pancreatic β-cells.
    Ribeiro RA; Santos-Silva JC; Vettorazzi JF; Cotrim BB; Mobiolli DD; Boschero AC; Carneiro EM
    Amino Acids; 2012 Oct; 43(4):1791-801. PubMed ID: 22418865
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Alterations in growth and apoptosis of insulin receptor substrate-1-deficient beta-cells.
    Hennige AM; Ozcan U; Okada T; Jhala US; Schubert M; White MF; Kulkarni RN
    Am J Physiol Endocrinol Metab; 2005 Aug; 289(2):E337-46. PubMed ID: 15827066
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Ontogenetic characteristics of enzyme activities and plasma metabolites in C57BL/6J:Jcl mice deficient in insulin receptor substrate 2.
    Hashimoto H; Arai T; Takeguchi A; Hioki K; Ohnishi Y; Kawai K; Ito M; Suzuki R; Yamauchi T; Ohsugi M; Saito M; Ueyama Y; Tobe K; Kadowaki T; Tamaoki N; Kosaka K
    Comp Med; 2006 Jun; 56(3):176-87. PubMed ID: 16774126
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Disruption of the SH2-B gene causes age-dependent insulin resistance and glucose intolerance.
    Duan C; Yang H; White MF; Rui L
    Mol Cell Biol; 2004 Sep; 24(17):7435-43. PubMed ID: 15314154
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2.
    Kido Y; Burks DJ; Withers D; Bruning JC; Kahn CR; White MF; Accili D
    J Clin Invest; 2000 Jan; 105(2):199-205. PubMed ID: 10642598
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes.
    Hennige AM; Burks DJ; Ozcan U; Kulkarni RN; Ye J; Park S; Schubert M; Fisher TL; Dow MA; Leshan R; Zakaria M; Mossa-Basha M; White MF
    J Clin Invest; 2003 Nov; 112(10):1521-32. PubMed ID: 14617753
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.