These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

184 related articles for article (PubMed ID: 15469908)

  • 21. Topoisomerase I-mediated DNA cleavage induced by the minor groove-directed binding of bibenzimidazoles to a distal site.
    Khan QA; Pilch DS
    J Mol Biol; 2007 Jan; 365(3):561-9. PubMed ID: 17095016
    [TBL] [Abstract][Full Text] [Related]  

  • 22. LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures.
    Pabon-Martinez YV; Xu Y; Villa A; Lundin KE; Geny S; Nguyen CH; Pedersen EB; Jørgensen PT; Wengel J; Nilsson L; Smith CIE; Zain R
    Sci Rep; 2017 Sep; 7(1):11043. PubMed ID: 28887512
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Recognition and cleavage of DNA by rebeccamycin- or benzopyridoquinoxaline conjugated of triple helix-forming oligonucleotides.
    Arimondo PB; Moreau P; Boutorine A; Bailly C; Prudhomme M; Sun JS; Garestier T; Hélène C
    Bioorg Med Chem; 2000 Apr; 8(4):777-84. PubMed ID: 10819166
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Differential stabilization of eukaryotic DNA topoisomerase I cleavable complexes by camptothecin derivatives.
    Tanizawa A; Kohn KW; Kohlhagen G; Leteurtre F; Pommier Y
    Biochemistry; 1995 May; 34(21):7200-6. PubMed ID: 7766631
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Mechanistic studies of the modulation of cleavage activity of topoisomerase I by DNA adducts of mono- and bi-functional PtII complexes.
    Malina J; Vrana O; Brabec V
    Nucleic Acids Res; 2009 Sep; 37(16):5432-42. PubMed ID: 19589806
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Evaluation of two models for human topoisomerase I interaction with dsDNA and camptothecin derivatives.
    Laco GS
    PLoS One; 2011; 6(8):e24314. PubMed ID: 21912628
    [TBL] [Abstract][Full Text] [Related]  

  • 27. The modulation of topoisomerase I-mediated DNA cleavage and the induction of DNA-topoisomerase I crosslinks by crotonaldehyde-derived DNA adducts.
    Dexheimer TS; Kozekova A; Rizzo CJ; Stone MP; Pommier Y
    Nucleic Acids Res; 2008 Jul; 36(12):4128-36. PubMed ID: 18550580
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Mammalian DNA topoisomerase I activity and poisoning by camptothecin are inhibited by simian virus 40 large T antigen.
    Pommier Y; Kohlhagen G; Wu C; Simmons DT
    Biochemistry; 1998 Mar; 37(11):3818-23. PubMed ID: 9521701
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Human topoisomerase I inhibition: docking camptothecin and derivatives into a structure-based active site model.
    Laco GS; Collins JR; Luke BT; Kroth H; Sayer JM; Jerina DM; Pommier Y
    Biochemistry; 2002 Feb; 41(5):1428-35. PubMed ID: 11814334
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Interaction of human nuclear topoisomerase I with guanosine quartet-forming and guanosine-rich single-stranded DNA and RNA oligonucleotides.
    Marchand C; Pourquier P; Laco GS; Jing N; Pommier Y
    J Biol Chem; 2002 Mar; 277(11):8906-11. PubMed ID: 11756434
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Sequence-specific base pair mimics are efficient topoisomerase IB inhibitors.
    Vekhoff P; Duca M; Guianvarc'h D; Benhida R; Arimondo PB
    Biochemistry; 2012 Jan; 51(1):43-51. PubMed ID: 22124209
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Molecular modeling studies of the DNA-topoisomerase I ternary cleavable complex with camptothecin.
    Fan Y; Weinstein JN; Kohn KW; Shi LM; Pommier Y
    J Med Chem; 1998 Jun; 41(13):2216-26. PubMed ID: 9632354
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Par-4 binds to topoisomerase 1 and attenuates its DNA relaxation activity.
    Goswami A; Qiu S; Dexheimer TS; Ranganathan P; Burikhanov R; Pommier Y; Rangnekar VM
    Cancer Res; 2008 Aug; 68(15):6190-8. PubMed ID: 18676842
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Modulation in kinetics of lactone ring hydrolysis of camptothecins upon interaction with topoisomerase I cleavage sites on DNA.
    Chourpa I; Riou JF; Millot JM; Pommier Y; Manfait M
    Biochemistry; 1998 May; 37(20):7284-91. PubMed ID: 9585542
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Triple helix-forming oligonucleotides conjugated to indolocarbazole poisons direct topoisomerase I-mediated DNA cleavage to a specific site.
    Arimondo PB; Bailly C; Boutorine AS; Moreau P; Prudhomme M; Sun JS; Garestier T; Hélène C
    Bioconjug Chem; 2001; 12(4):501-9. PubMed ID: 11459453
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states.
    Takahashi DT; Gadelle D; Agama K; Kiselev E; Zhang H; Yab E; Petrella S; Forterre P; Pommier Y; Mayer C
    Nat Commun; 2022 Jan; 13(1):59. PubMed ID: 35013228
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Benzo[a]pyrene diol epoxide adducts in DNA are potent suppressors of a normal topoisomerase I cleavage site and powerful inducers of other topoisomerase I cleavages.
    Pommier Y; Kohlhagen G; Pourquier P; Sayer JM; Kroth H; Jerina DM
    Proc Natl Acad Sci U S A; 2000 Feb; 97(5):2040-5. PubMed ID: 10688881
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A camptothecin-resistant DNA topoisomerase I mutant exhibits altered sensitivities to other DNA topoisomerase poisons.
    Knab AM; Fertala J; Bjornsti MA
    J Biol Chem; 1995 Mar; 270(11):6141-8. PubMed ID: 7890748
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Topoisomerase I alone is sufficient to produce short DNA deletions and can also reverse nicks at ribonucleotide sites.
    Huang SY; Ghosh S; Pommier Y
    J Biol Chem; 2015 May; 290(22):14068-76. PubMed ID: 25887397
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Recognition of RNA duplexes by chemically modified triplex-forming oligonucleotides.
    Zhou Y; Kierzek E; Loo ZP; Antonio M; Yau YH; Chuah YW; Geifman-Shochat S; Kierzek R; Chen G
    Nucleic Acids Res; 2013 Jul; 41(13):6664-73. PubMed ID: 23658228
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 10.