210 related articles for article (PubMed ID: 15476669)
1. 2-Substituted adenosine derivatives: affinity and efficacy at four subtypes of human adenosine receptors.
Gao ZG; Mamedova LK; Chen P; Jacobson KA
Biochem Pharmacol; 2004 Nov; 68(10):1985-93. PubMed ID: 15476669
[TBL] [Abstract][Full Text] [Related]
2. N6-Substituted adenosine derivatives: selectivity, efficacy, and species differences at A3 adenosine receptors.
Gao ZG; Blaustein JB; Gross AS; Melman N; Jacobson KA
Biochem Pharmacol; 2003 May; 65(10):1675-84. PubMed ID: 12754103
[TBL] [Abstract][Full Text] [Related]
3. N(6)-alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A(3) receptor and a starting point for searching A(2B) ligands.
Volpini R; Costanzi S; Lambertucci C; Taffi S; Vittori S; Klotz KN; Cristalli G
J Med Chem; 2002 Jul; 45(15):3271-9. PubMed ID: 12109910
[TBL] [Abstract][Full Text] [Related]
4. Design, synthesis, and biological evaluation of new 8-heterocyclic xanthine derivatives as highly potent and selective human A2B adenosine receptor antagonists.
Baraldi PG; Tabrizi MA; Preti D; Bovero A; Romagnoli R; Fruttarolo F; Zaid NA; Moorman AR; Varani K; Gessi S; Merighi S; Borea PA
J Med Chem; 2004 Mar; 47(6):1434-47. PubMed ID: 14998332
[TBL] [Abstract][Full Text] [Related]
5. Selectivity is species-dependent: Characterization of standard agonists and antagonists at human, rat, and mouse adenosine receptors.
Alnouri MW; Jepards S; Casari A; Schiedel AC; Hinz S; Müller CE
Purinergic Signal; 2015 Sep; 11(3):389-407. PubMed ID: 26126429
[TBL] [Abstract][Full Text] [Related]
6. 1,3-dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships.
Fernández F; Caamaño O; Isabel Nieto M; López C; García-Mera X; Stefanachi A; Nicolotti O; Isabel Loza M; Brea J; Esteve C; Segarra V; Vidal B; Carotti A
Bioorg Med Chem; 2009 May; 17(10):3618-29. PubMed ID: 19398343
[TBL] [Abstract][Full Text] [Related]
7. Structural determinants of efficacy at A3 adenosine receptors: modification of the ribose moiety.
Gao ZG; Jeong LS; Moon HR; Kim HO; Choi WJ; Shin DH; Elhalem E; Comin MJ; Melman N; Mamedova L; Gross AS; Rodriguez JB; Jacobson KA
Biochem Pharmacol; 2004 Mar; 67(5):893-901. PubMed ID: 15104242
[TBL] [Abstract][Full Text] [Related]
8. Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.
Klotz KN; Hessling J; Hegler J; Owman C; Kull B; Fredholm BB; Lohse MJ
Naunyn Schmiedebergs Arch Pharmacol; 1998 Jan; 357(1):1-9. PubMed ID: 9459566
[TBL] [Abstract][Full Text] [Related]
9. 1,8-disubstituted xanthine derivatives: synthesis of potent A2B-selective adenosine receptor antagonists.
Hayallah AM; Sandoval-Ramírez J; Reith U; Schobert U; Preiss B; Schumacher B; Daly JW; Müller CE
J Med Chem; 2002 Mar; 45(7):1500-10. PubMed ID: 11906291
[TBL] [Abstract][Full Text] [Related]
10. Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.
Linden J; Thai T; Figler H; Jin X; Robeva AS
Mol Pharmacol; 1999 Oct; 56(4):705-13. PubMed ID: 10496952
[TBL] [Abstract][Full Text] [Related]
11. 2-Phenylimidazo[2,1-i]purin-5-ones: structure-activity relationships and characterization of potent and selective inverse agonists at Human A3 adenosine receptors.
Ozola V; Thorand M; Diekmann M; Qurishi R; Schumacher B; Jacobson KA; Müller CE
Bioorg Med Chem; 2003 Feb; 11(3):347-56. PubMed ID: 12517430
[TBL] [Abstract][Full Text] [Related]
12. Anilide derivatives of an 8-phenylxanthine carboxylic congener are highly potent and selective antagonists at human A(2B) adenosine receptors.
Kim YC; Ji X; Melman N; Linden J; Jacobson KA
J Med Chem; 2000 Mar; 43(6):1165-72. PubMed ID: 10737749
[TBL] [Abstract][Full Text] [Related]
13. 5'-O-alkyl ethers of N,2-substituted adenosine derivatives: partial agonists for the adenosine A1 and A3 receptors.
van Tilburg EW; van der Klein PA; von Frijtag Drabbe Künzel J; de Groote M; Stannek C; Lorenzen A; IJzerman AP
J Med Chem; 2001 Aug; 44(18):2966-75. PubMed ID: 11520205
[TBL] [Abstract][Full Text] [Related]
14. Pharmacological characterisation and inhibitory effects of (2R,3R,4S,5R)-2-(6-amino-2-{[(1S)-2-hydroxy-1-(phenylmethyl)ethyl]amino}-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydro-3,4-furandiol, a novel ligand that demonstrates both adenosine A(2A) receptor agonist and adenosine A(3) receptor antagonist activity.
Bevan N; Butchers PR; Cousins R; Coates J; Edgar EV; Morrison V; Sheehan MJ; Reeves J; Wilson DJ
Eur J Pharmacol; 2007 Jun; 564(1-3):219-25. PubMed ID: 17382926
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and pharmacological evaluation of novel 1,3,8- and 1,3,7,8-substituted xanthines as adenosine receptor antagonists.
Rodríguez-Borges JE; García-Mera X; Balo MC; Brea J; Caamaño O; Fernández F; López C; Loza MI; Nieto MI
Bioorg Med Chem; 2010 Mar; 18(5):2001-9. PubMed ID: 20137957
[TBL] [Abstract][Full Text] [Related]
16. Chalcone-based derivatives as new scaffolds for hA3 adenosine receptor antagonists.
Vazquez-Rodriguez S; Matos MJ; Santana L; Uriarte E; Borges F; Kachler S; Klotz KN
J Pharm Pharmacol; 2013 May; 65(5):697-703. PubMed ID: 23600387
[TBL] [Abstract][Full Text] [Related]
17. Structure-activity relationships of truncated adenosine derivatives as highly potent and selective human A3 adenosine receptor antagonists.
Pal S; Choi WJ; Choe SA; Heller CL; Gao ZG; Chinn M; Jacobson KA; Hou X; Lee SK; Kim HO; Jeong LS
Bioorg Med Chem; 2009 May; 17(10):3733-8. PubMed ID: 19375920
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and pharmacological evaluation of novel 1- and 8-substituted-3-furfuryl xanthines as adenosine receptor antagonists.
Balo MC; Brea J; Caamaño O; Fernández F; García-Mera X; López C; Loza MI; Nieto MI; Rodríguez-Borges JE
Bioorg Med Chem; 2009 Sep; 17(18):6755-60. PubMed ID: 19682912
[TBL] [Abstract][Full Text] [Related]
19. 2,5'-Disubstituted adenosine derivatives: evaluation of selectivity and efficacy for the adenosine A(1), A(2A), and A(3) receptor.
van Tilburg EW; von Frijtag Drabbe Kunzel J; de Groote M; IJzerman AP
J Med Chem; 2002 Jan; 45(2):420-9. PubMed ID: 11784146
[TBL] [Abstract][Full Text] [Related]
20. Selective allosteric enhancement of agonist binding and function at human A3 adenosine receptors by a series of imidazoquinoline derivatives.
Gao ZG; Kim SG; Soltysiak KA; Melman N; IJzerman AP; Jacobson KA
Mol Pharmacol; 2002 Jul; 62(1):81-9. PubMed ID: 12065758
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
