201 related articles for article (PubMed ID: 15481981)
1. Influence of the linker in bispyridium compounds on the inhibition of human choline kinase.
Conejo-García A; Báñez-Coronel M; Sánchez-Martín RM; Rodríguez-González A; Ramos A; Ramírez de Molina A; Espinosa A; Gallo MA; Campos JM; Lacal JC
J Med Chem; 2004 Oct; 47(22):5433-40. PubMed ID: 15481981
[TBL] [Abstract][Full Text] [Related]
2. Novel 4-amino bis-pyridinium and bis-quinolinium derivatives as choline kinase inhibitors with antiproliferative activity against the human breast cancer SKBR-3 cell line.
Gómez-Pérez V; McSorley T; See Too WC; Konrad M; Campos JM
ChemMedChem; 2012 Apr; 7(4):663-9. PubMed ID: 22278967
[TBL] [Abstract][Full Text] [Related]
3. Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line.
Sánchez-Martín R; Campos JM; Conejo-García A; Cruz-López O; Báñez-Coronel M; Rodríguez-González A; Gallo MA; Lacal JC; Espinosa A
J Med Chem; 2005 May; 48(9):3354-63. PubMed ID: 15857141
[TBL] [Abstract][Full Text] [Related]
4. Bispyridinium cyclophanes: novel templates for human choline kinase inhibitors.
Conejo-García A; Campos JM; Sánchez-Martín RM; Gallo MA; Espinosa A
J Med Chem; 2003 Aug; 46(17):3754-7. PubMed ID: 12904080
[TBL] [Abstract][Full Text] [Related]
5. Choline kinase inhibitory effect and antiproliferative activity of new 1,1',1"-(benzene-1,3,5-triylmethylene)tris[4-[(disubstituted)amino]pyridinium] tribromides.
Conejo-García A; Campos J; Sánchez RM; Rodríguez-González A; Lacal JC; Gallo MA; Espinosa A
Eur J Med Chem; 2003 Jan; 38(1):109-16. PubMed ID: 12593921
[TBL] [Abstract][Full Text] [Related]
6. LUMO energy of model compounds of bispyridinium compounds as an index for the inhibition of choline kinase.
Campos J; del Carmen Núñez M; Rodríguez V; Entrena A; Hernández-Alcoceba R; Fernández F; Lacal JC; Gallo MA; Espinosa A
Eur J Med Chem; 2001 Mar; 36(3):215-25. PubMed ID: 11337100
[TBL] [Abstract][Full Text] [Related]
7. Lead optimization-hit expansion of new asymmetrical pyridinium/quinolinium compounds as choline kinase α1 inhibitors.
Rubbini G; Buades-Martín AB; Kimatrai-Salvador M; Entrena A; Gallo-Mezo MÁ; Ríos-Marco P; Marco C; Mattiuzzo E; Bortolozzi R; Mariotto E; Greco FA; Macchiarulo A; Carrasco-Jiménez MP; Viola G; López-Cara LC
Future Med Chem; 2018 Aug; 10(15):1769-1786. PubMed ID: 30043647
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological activity of new bispyridinium salts of 4,4'-bispyridyl-5,5'-perfluoroalkyl-2,2'-bisoxazoles.
Martín-Cantalejo Y; Sáez B; Monterde MI; Murillo MT; Braña MF
Eur J Med Chem; 2011 Nov; 46(11):5662-7. PubMed ID: 21996467
[TBL] [Abstract][Full Text] [Related]
9. Bispyridinium dienes: histone deacetylase inhibitors with selective activities.
Pérez-Balado C; Nebbioso A; Rodríguez-Graña P; Minichiello A; Miceli M; Altucci L; de Lera AR
J Med Chem; 2007 May; 50(10):2497-505. PubMed ID: 17447750
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity.
Cincinelli R; Dallavalle S; Nannei R; Carella S; De Zani D; Merlini L; Penco S; Garattini E; Giannini G; Pisano C; Vesci L; Carminati P; Zuco V; Zanchi C; Zunino F
J Med Chem; 2005 Jul; 48(15):4931-46. PubMed ID: 16033272
[TBL] [Abstract][Full Text] [Related]
11. (Q)SAR studies to design new human choline kinase inhibitors as antiproliferative drugs.
Campos JM; Sánchez-Martín RM; Conejo-García A; Entrena A; Gallo MA; Espinosa A
Curr Med Chem; 2006; 13(11):1231-48. PubMed ID: 16712467
[TBL] [Abstract][Full Text] [Related]
12. Design, synthesis and structure-activity relationships of antiproliferative 1,3-disubstituted urea derivatives.
Li HQ; Zhu TT; Yan T; Luo Y; Zhu HL
Eur J Med Chem; 2009 Feb; 44(2):453-9. PubMed ID: 18514972
[TBL] [Abstract][Full Text] [Related]
13. Discovery of antiglioma activity of biaryl 1,2,3,4-tetrahydroisoquinoline derivatives and conformationally flexible analogues.
Mohler ML; Kang GS; Hong SS; Patil R; Kirichenko OV; Li W; Rakov IM; Geisert EE; Miller DD
J Med Chem; 2006 Sep; 49(19):5845-8. PubMed ID: 16970409
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of ChoK is an efficient antitumor strategy for Harvey-, Kirsten-, and N-ras-transformed cells.
Ramírez de Molina A; Rodríguez-González A; Penalva V; Lucas L; Lacal JC
Biochem Biophys Res Commun; 2001 Jul; 285(4):873-9. PubMed ID: 11467831
[TBL] [Abstract][Full Text] [Related]
15. Design, synthesis, crystallization and biological evaluation of new symmetrical biscationic compounds as selective inhibitors of human Choline Kinase α1 (ChoKα1).
Schiaffino-Ortega S; Baglioni E; Mariotto E; Bortolozzi R; Serrán-Aguilera L; Ríos-Marco P; Carrasco-Jimenez MP; Gallo MA; Hurtado-Guerrero R; Marco C; Basso G; Viola G; Entrena A; López-Cara LC
Sci Rep; 2016 Mar; 6():23793. PubMed ID: 27029499
[TBL] [Abstract][Full Text] [Related]
16. Noninvasive magnetic resonance spectroscopic pharmacodynamic markers of the choline kinase inhibitor MN58b in human carcinoma models.
Al-Saffar NM; Troy H; Ramírez de Molina A; Jackson LE; Madhu B; Griffiths JR; Leach MO; Workman P; Lacal JC; Judson IR; Chung YL
Cancer Res; 2006 Jan; 66(1):427-34. PubMed ID: 16397258
[TBL] [Abstract][Full Text] [Related]
17. QSAR-derived choline kinase inhibitors: how rational can antiproliferative drug design be?
Campos J; Núñez MC; Conejo-García A; Sánchez-Martín RM; Hernández-Alcoceba R; Rodríguez-González A; Lacal JC; Gallo MA; Espinosa A
Curr Med Chem; 2003 Jul; 10(13):1095-112. PubMed ID: 12678804
[TBL] [Abstract][Full Text] [Related]
18. Choline kinase inhibitors as a novel approach for antiproliferative drug design.
Hernández-Alcoceba R; Saniger L; Campos J; Núñez MC; Khaless F; Gallo MA; Espinosa A; Lacal JC
Oncogene; 1997 Nov; 15(19):2289-301. PubMed ID: 9393874
[TBL] [Abstract][Full Text] [Related]
19. Design, synthesis, enzyme inhibition, and tumor cell growth inhibition of 2-anilinobenzamide derivatives as SIRT1 inhibitors.
Suzuki T; Imai K; Imai E; Iida S; Ueda R; Tsumoto H; Nakagawa H; Miyata N
Bioorg Med Chem; 2009 Aug; 17(16):5900-5. PubMed ID: 19616958
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and evaluation of novel 7-azaindazolyl-indolyl-maleimide derivatives as antitumor agents and protein kinase C inhibitors.
Ye Q; Cao J; Zhou X; Lv D; He Q; Yang B; Hu Y
Bioorg Med Chem; 2009 Jul; 17(13):4763-72. PubMed ID: 19447039
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
