BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

191 related articles for article (PubMed ID: 15482257)

  • 1. Determination of the minimal functional ligand-binding domain of the GABAB1b receptor.
    Deriu D; Gassmann M; Firbank S; Ristig D; Lampert C; Mosbacher J; Froestl W; Kaupmann K; Bettler B; Grütter MG
    Biochem J; 2005 Mar; 386(Pt 3):423-31. PubMed ID: 15482257
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The heptahelical domain of GABA(B2) is activated directly by CGP7930, a positive allosteric modulator of the GABA(B) receptor.
    Binet V; Brajon C; Le Corre L; Acher F; Pin JP; Prézeau L
    J Biol Chem; 2004 Jul; 279(28):29085-91. PubMed ID: 15126507
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The C-terminal domains of the GABA(b) receptor subunits mediate intracellular trafficking but are not required for receptor signaling.
    Calver AR; Robbins MJ; Cosio C; Rice SQ; Babbs AJ; Hirst WD; Boyfield I; Wood MD; Russell RB; Price GW; Couve A; Moss SJ; Pangalos MN
    J Neurosci; 2001 Feb; 21(4):1203-10. PubMed ID: 11160390
    [TBL] [Abstract][Full Text] [Related]  

  • 4. GABA(B) receptor subunit 1 binds to proteins affected in 22q11 deletion syndrome.
    Zunner D; Deschermeier C; Kornau HC
    Biochem Biophys Res Commun; 2010 Mar; 393(2):185-9. PubMed ID: 20036641
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparative immunohistochemical localisation of GABA(B1a), GABA(B1b) and GABA(B2) subunits in rat brain, spinal cord and dorsal root ganglion.
    Charles KJ; Evans ML; Robbins MJ; Calver AR; Leslie RA; Pangalos MN
    Neuroscience; 2001; 106(3):447-67. PubMed ID: 11591450
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Functioning of the dimeric GABA(B) receptor extracellular domain revealed by glycan wedge scanning.
    Rondard P; Huang S; Monnier C; Tu H; Blanchard B; Oueslati N; Malhaire F; Li Y; Trinquet E; Labesse G; Pin JP; Liu J
    EMBO J; 2008 May; 27(9):1321-32. PubMed ID: 18388862
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Characterization of gamma-aminobutyric acid receptor GABAB(1e), a GABAB(1) splice variant encoding a truncated receptor.
    Schwarz DA; Barry G; Eliasof SD; Petroski RE; Conlon PJ; Maki RA
    J Biol Chem; 2000 Oct; 275(41):32174-81. PubMed ID: 10906333
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular mechanisms of GABA(B) receptor activation: new insights from the mechanism of action of CGP7930, a positive allosteric modulator.
    Binet V; Goudet C; Brajon C; Le Corre L; Acher F; Pin JP; Prézeau L
    Biochem Soc Trans; 2004 Nov; 32(Pt 5):871-2. PubMed ID: 15494037
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ligand-induced signal transduction within heterodimeric GABA(B) receptor.
    Margeta-Mitrovic M; Jan YN; Jan LY
    Proc Natl Acad Sci U S A; 2001 Dec; 98(25):14643-8. PubMed ID: 11724957
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Point mutations in the transmembrane region of GABAB2 facilitate activation by the positive modulator N,N'-dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) in the absence of the GABAB1 subunit.
    Dupuis DS; Relkovic D; Lhuillier L; Mosbacher J; Kaupmann K
    Mol Pharmacol; 2006 Dec; 70(6):2027-36. PubMed ID: 16966477
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cloning and characterization of a novel variant of rat GABA(B)R1 with a truncated C-terminus.
    Wei K; Jia Z; Wang YT; Yang J; Liu CC; Snead OC
    Brain Res Mol Brain Res; 2001 Apr; 89(1-2):103-10. PubMed ID: 11311980
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The sushi domains of secreted GABA(B1) isoforms selectively impair GABA(B) heteroreceptor function.
    Tiao JY; Bradaia A; Biermann B; Kaupmann K; Metz M; Haller C; Rolink AG; Pless E; Barlow PN; Gassmann M; Bettler B
    J Biol Chem; 2008 Nov; 283(45):31005-11. PubMed ID: 18765663
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Allosteric interactions between GB1 and GB2 subunits are required for optimal GABA(B) receptor function.
    Galvez T; Duthey B; Kniazeff J; Blahos J; Rovelli G; Bettler B; Prézeau L; Pin JP
    EMBO J; 2001 May; 20(9):2152-9. PubMed ID: 11331581
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation mechanism of the heterodimeric GABA(B) receptor.
    Pin JP; Kniazeff J; Binet V; Liu J; Maurel D; Galvez T; Duthey B; Havlickova M; Blahos J; Prézeau L; Rondard P
    Biochem Pharmacol; 2004 Oct; 68(8):1565-72. PubMed ID: 15451400
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Gabapentin is not a GABAB receptor agonist.
    Lanneau C; Green A; Hirst WD; Wise A; Brown JT; Donnier E; Charles KJ; Wood M; Davies CH; Pangalos MN
    Neuropharmacology; 2001 Dec; 41(8):965-75. PubMed ID: 11747901
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Native GABA(B) receptors are heteromultimers with a family of auxiliary subunits.
    Schwenk J; Metz M; Zolles G; Turecek R; Fritzius T; Bildl W; Tarusawa E; Kulik A; Unger A; Ivankova K; Seddik R; Tiao JY; Rajalu M; Trojanova J; Rohde V; Gassmann M; Schulte U; Fakler B; Bettler B
    Nature; 2010 May; 465(7295):231-5. PubMed ID: 20400944
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Signal transduction by GABA(B) receptor heterodimers.
    Jones KA; Tamm JA; Craig DA; Ph D; Yao W; Panico R
    Neuropsychopharmacology; 2000 Oct; 23(4 Suppl):S41-9. PubMed ID: 11008066
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heterodimerization is required for the formation of a functional GABA(B) receptor.
    White JH; Wise A; Main MJ; Green A; Fraser NJ; Disney GH; Barnes AA; Emson P; Foord SM; Marshall FH
    Nature; 1998 Dec; 396(6712):679-82. PubMed ID: 9872316
    [TBL] [Abstract][Full Text] [Related]  

  • 19. GABAB receptor complex as a potential target for tumor therapy.
    Jiang X; Su L; Zhang Q; He C; Zhang Z; Yi P; Liu J
    J Histochem Cytochem; 2012 Apr; 60(4):269-79. PubMed ID: 22266766
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Subtype-selective interaction with the transcription factor CCAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) regulates cell surface expression of GABA(B) receptors.
    Sauter K; Grampp T; Fritschy JM; Kaupmann K; Bettler B; Mohler H; Benke D
    J Biol Chem; 2005 Sep; 280(39):33566-72. PubMed ID: 16081421
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.