BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 15482939)

  • 1. Synthesis of 5'-substituted fluoro-neplanocin A analogues: importance of a hydrogen bonding donor at 5'-position for the inhibitory activity of S-adenosylhomocysteine hydrolase.
    Moon HR; Lee HJ; Kim KR; Lee KM; Lee SK; Kim HO; Chun MW; Jeong LS
    Bioorg Med Chem Lett; 2004 Nov; 14(22):5641-4. PubMed ID: 15482939
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-activity relationship of 5'-substituted fluoro-neplanocin a analogues as potent inhibitors of S-adenosylhomocysteine hydrolase.
    Moon HR; Lee KM; Lee JH; Lee SK; Park SB; Chun MW; Jeong LS
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(5-7):707-8. PubMed ID: 16248019
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of halogenated 9-(dihydroxycyclopent-4'-enyl) adenines and their inhibitory activities against S-adenosylhomocysteine hydrolase.
    Jeong LS; Park JG; Choi WJ; Moon HR; Lee KM; Kim HO; Kim HD; Chun MW; Park HY; Kim K; Sheen YY
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):919-21. PubMed ID: 14565311
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis, and in vitro evaluation of APIO analogue of neplanocin A.
    Moon HR; Kwon SH; Lee JA; Yoo BN; Kim HO; Chun MW; Kim HD; Kim JH; Jeong LS
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1475-7. PubMed ID: 14565446
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis of 5'-methylenearisteromycin and its 2-fluoro derivative with potent antimalarial activity due to inhibition of the parasite S-adenosylhomocysteine hydrolase.
    Takagi C; Sukeda M; Kim HS; Wataya Y; Yabe S; Kitade Y; Matsuda A; Shuto S
    Org Biomol Chem; 2005 Apr; 3(7):1245-51. PubMed ID: 15785814
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis and biological evaluation of halo-neplanocin A as novel mechanism-based inhibitors of S-adenosylhomocysteine hydrolase.
    Jeong LS; Moon HR; Park JG; Shin DH; Choi WJ; Lee KM; Kim HO; Chun MW; Kim HD; Kim JH
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):589-92. PubMed ID: 14565234
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis of novel 4'-modified neplanocin A analogues and their inhibitory activity against S-adenosyl-L-l-homocysteine hydrolase.
    Kumamoto H; Deguchi K; Takahashi N; Tanaka H; Kitade Y
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(6-7):733-6. PubMed ID: 18066891
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and molecular modeling studies of 5'-deoxy-5'-ureidoadenosine: 5'-ureido group as multiple hydrogen bonding donor in the active site of S-adenosylhomocysteine hydrolase.
    Wang T; Lee HJ; Tosh DK; Kim HO; Pal S; Choi S; Lee Y; Moon HR; Zhao LX; Lee KM; Jeong LS
    Bioorg Med Chem Lett; 2007 Aug; 17(16):4456-9. PubMed ID: 17582766
    [TBL] [Abstract][Full Text] [Related]  

  • 9. S-Adenosylhomocysteine hydrolase of the protozoan parasite Trichomonas vaginalis: potent inhibitory activity of 9-(2-deoxy-2-fluoro-β,D-arabinofuranosyl)adenine.
    Shokar A; Au A; An SH; Tong E; Garza G; Zayas J; Wnuk SF; Land KM
    Bioorg Med Chem Lett; 2012 Jun; 22(12):4203-5. PubMed ID: 22579483
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities.
    Chandra G; Moon YW; Lee Y; Jang JY; Song J; Nayak A; Oh K; Mulamoottil VA; Sahu PK; Kim G; Chang TS; Noh M; Lee SK; Choi S; Jeong LS
    J Med Chem; 2015 Jun; 58(12):5108-20. PubMed ID: 26010585
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Truncated fluorocyclopentenyl pyrimidines as S-adenosylhomocysteine hydrolase inhibitors.
    Park YH; Choi WJ; Tipnis AS; Lee KM; Jeong LS
    Nucleosides Nucleotides Nucleic Acids; 2009 May; 28(5):601-13. PubMed ID: 20183604
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis of 4'-modified noraristeromycins to clarify the effect of the 4'-hydroxyl groups for inhibitory activity against S-adenosyl-L-homocysteine hydrolase.
    Ando T; Kojima K; Chahota P; Kozaki A; Milind ND; Kitade Y
    Bioorg Med Chem Lett; 2008 Apr; 18(8):2615-8. PubMed ID: 18374570
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 4'-Fluorinated carbocyclic nucleosides: synthesis and inhibitory activity against S-adenosyl-L-homocysteine hydrolase.
    Kitade Y; Ando T; Yamaguchi T; Hori A; Nakanishi M; Ueno Y
    Bioorg Med Chem; 2006 Aug; 14(16):5578-83. PubMed ID: 16682206
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and biological activity of novel acyclic versions of Neplanocin A.
    Wu Y; Hong JH
    Arch Pharm (Weinheim); 2005 Nov; 338(11):517-21. PubMed ID: 16281309
    [TBL] [Abstract][Full Text] [Related]  

  • 15. X-ray crystal structure and binding mode analysis of human S-adenosylhomocysteine hydrolase complexed with novel mechanism-based inhibitors, haloneplanocin A analogues.
    Lee KM; Choi WJ; Lee Y; Lee HJ; Zhao LX; Lee HW; Park JG; Kim HO; Hwang KY; Heo YS; Choi S; Jeong LS
    J Med Chem; 2011 Feb; 54(4):930-8. PubMed ID: 21226494
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis of 2-modified aristeromycins and their analogs as potent inhibitors against Plasmodium falciparum S-adenosyl-L-homocysteine hydrolase.
    Ando T; Iwata M; Zulfiqar F; Miyamoto T; Nakanishi M; Kitade Y
    Bioorg Med Chem; 2008 Apr; 16(7):3809-15. PubMed ID: 18295495
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis of apio analogues of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase.
    Lee JA; Yoo BN; Choi WJ; Moon HR; Jeong LS
    Nucleic Acids Res Suppl; 2003; (3):15-6. PubMed ID: 14510357
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis of novel apio carbocyclic nucleoside analogues as selective a(3) adenosine receptor agonists.
    Lee JA; Moon HR; Kim HO; Kim KR; Lee KM; Kim BT; Hwang KJ; Chun MW; Jacobson KA; Jeong LS
    J Org Chem; 2005 Jun; 70(13):5006-13. PubMed ID: 15960499
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and biological evaluation of fluoroneplanocin A as the novel mechanism-based inhibitor of S-adenosylhomocysteine hydrolase.
    Jeong LS; Yoo SJ; Lee KM; Koo MJ; Choi WJ; Kim HO; Moon HR; Lee MY; Park JG; Lee SK; Chun MW
    J Med Chem; 2003 Jan; 46(2):201-3. PubMed ID: 12519056
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 4'-modified analogues of aristeromycin and neplanocin A: synthesis and inhibitory activity toward S-adenosyl-L-homocysteine hydrolase.
    Wolfe MS; Lee Y; Bartlett WJ; Borcherding DR; Borchardt RT
    J Med Chem; 1992 May; 35(10):1782-91. PubMed ID: 1588558
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.