BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

338 related articles for article (PubMed ID: 15485932)

  • 1. Serine phosphorylation proximal to its phosphotyrosine binding domain inhibits insulin receptor substrate 1 function and promotes insulin resistance.
    Liu YF; Herschkovitz A; Boura-Halfon S; Ronen D; Paz K; Leroith D; Zick Y
    Mol Cell Biol; 2004 Nov; 24(21):9668-81. PubMed ID: 15485932
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Angiotensin II impairs the insulin signaling pathway promoting production of nitric oxide by inducing phosphorylation of insulin receptor substrate-1 on Ser312 and Ser616 in human umbilical vein endothelial cells.
    Andreozzi F; Laratta E; Sciacqua A; Perticone F; Sesti G
    Circ Res; 2004 May; 94(9):1211-8. PubMed ID: 15044323
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Muscarinic-receptor-mediated inhibition of insulin-like growth factor-1 receptor-stimulated phosphoinositide 3-kinase signalling in 1321N1 astrocytoma cells.
    Batty IH; Fleming IN; Downes CP
    Biochem J; 2004 May; 379(Pt 3):641-51. PubMed ID: 14769130
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Positive and negative regulation of insulin signaling through IRS-1 phosphorylation.
    Gual P; Le Marchand-Brustel Y; Tanti JF
    Biochimie; 2005 Jan; 87(1):99-109. PubMed ID: 15733744
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mammalian target of rapamycin pathway regulates insulin signaling via subcellular redistribution of insulin receptor substrate 1 and integrates nutritional signals and metabolic signals of insulin.
    Takano A; Usui I; Haruta T; Kawahara J; Uno T; Iwata M; Kobayashi M
    Mol Cell Biol; 2001 Aug; 21(15):5050-62. PubMed ID: 11438661
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In vitro phosphorylation of insulin receptor substrate 1 by protein kinase C-zeta: functional analysis and identification of novel phosphorylation sites.
    Sommerfeld MR; Metzger S; Stosik M; Tennagels N; Eckel J
    Biochemistry; 2004 May; 43(19):5888-901. PubMed ID: 15134463
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling.
    Luo M; Langlais P; Yi Z; Lefort N; De Filippis EA; Hwang H; Christ-Roberts CY; Mandarino LJ
    Endocrinology; 2007 Oct; 148(10):4895-905. PubMed ID: 17640984
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function.
    Paz K; Liu YF; Shorer H; Hemi R; LeRoith D; Quan M; Kanety H; Seger R; Zick Y
    J Biol Chem; 1999 Oct; 274(40):28816-22. PubMed ID: 10497255
    [TBL] [Abstract][Full Text] [Related]  

  • 9. PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function.
    Greene MW; Ruhoff MS; Roth RA; Kim JA; Quon MJ; Krause JA
    Biochem Biophys Res Commun; 2006 Oct; 349(3):976-86. PubMed ID: 16970908
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of major ERK-related phosphorylation sites in Gab1.
    Lehr S; Kotzka J; Avci H; Sickmann A; Meyer HE; Herkner A; Muller-Wieland D
    Biochemistry; 2004 Sep; 43(38):12133-40. PubMed ID: 15379552
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Insulin-induced serine phosphorylation of IRS-2 via ERK1/2 and mTOR: studies on the function of Ser675 and Ser907.
    Fritsche L; Neukamm SS; Lehmann R; Kremmer E; Hennige AM; Hunder-Gugel A; Schenk M; Häring HU; Schleicher ED; Weigert C
    Am J Physiol Endocrinol Metab; 2011 May; 300(5):E824-36. PubMed ID: 21098738
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Common inhibitory serine sites phosphorylated by IRS-1 kinases, triggered by insulin and inducers of insulin resistance.
    Herschkovitz A; Liu YF; Ilan E; Ronen D; Boura-Halfon S; Zick Y
    J Biol Chem; 2007 Jun; 282(25):18018-18027. PubMed ID: 17446166
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of insulin receptor substrate 1 serine/threonine phosphorylation sites using mass spectrometry analysis: regulatory role of serine 1223.
    Luo M; Reyna S; Wang L; Yi Z; Carroll C; Dong LQ; Langlais P; Weintraub ST; Mandarino LJ
    Endocrinology; 2005 Oct; 146(10):4410-6. PubMed ID: 16020478
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interferon-dependent activation of the serine kinase PI 3'-kinase requires engagement of the IRS pathway but not the Stat pathway.
    Uddin S; Majchrzak B; Wang PC; Modi S; Khan MK; Fish EN; Platanias LC
    Biochem Biophys Res Commun; 2000 Apr; 270(1):158-62. PubMed ID: 10733921
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of streptozocin diabetes and diabetes treatment by islet transplantation on in vivo insulin signaling in rat heart.
    Laviola L; Belsanti G; Davalli AM; Napoli R; Perrini S; Weir GC; Giorgino R; Giorgino F
    Diabetes; 2001 Dec; 50(12):2709-20. PubMed ID: 11723053
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Interaction of insulin receptor substrate-1 (IRS-1) with phosphatidylinositol 3-kinase: effect of substitution of serine for alanine in potential IRS-1 serine phosphorylation sites.
    Delahaye L; Mothe-Satney I; Myers MG; White MF; Van Obberghen E
    Endocrinology; 1998 Dec; 139(12):4911-9. PubMed ID: 9832428
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Molecular basis for the insulinomimetic effects of C-peptide.
    Grunberger G; Qiang X; Li Z; Mathews ST; Sbrissa D; Shisheva A; Sima AA
    Diabetologia; 2001 Oct; 44(10):1247-57. PubMed ID: 11692173
    [TBL] [Abstract][Full Text] [Related]  

  • 18. G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Galphaq/11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes.
    Usui I; Imamura T; Babendure JL; Satoh H; Lu JC; Hupfeld CJ; Olefsky JM
    Mol Endocrinol; 2005 Nov; 19(11):2760-8. PubMed ID: 15994203
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insulin-induced cell cycle progression is impaired in chinese hamster ovary cells overexpressing insulin receptor substrate-3.
    Kaburagi Y; Yamashita R; Ito Y; Okochi H; Yamamoto-Honda R; Yasuda K; Sekihara H; Sasazuki T; Kadowaki T; Yazaki Y
    Endocrinology; 2004 Dec; 145(12):5862-74. PubMed ID: 15331570
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Essential role of insulin receptor substrate 1 in differentiation of brown adipocytes.
    Fasshauer M; Klein J; Kriauciunas KM; Ueki K; Benito M; Kahn CR
    Mol Cell Biol; 2001 Jan; 21(1):319-29. PubMed ID: 11113206
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.