BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

251 related articles for article (PubMed ID: 15486077)

  • 1. Metabolism, pharmacokinetics, tissue distribution, and excretion of [14C]CP-424391 in rats.
    Khojasteh-Bakht SC; O'donnell JP; Fouda HG; Potchoiba MJ
    Drug Metab Dispos; 2005 Jan; 33(1):190-9. PubMed ID: 15486077
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Absorption, distribution, metabolism, and excretion of [¹⁴C]GDC-0449 (vismodegib), an orally active hedgehog pathway inhibitor, in rats and dogs: a unique metabolic pathway via pyridine ring opening.
    Yue Q; Chen YH; Mulder T; Deese A; Takahashi R; Rudewicz PJ; Reynolds M; Solon E; Hop CE; Wong H; Khojasteh SC
    Drug Metab Dispos; 2011 Jun; 39(6):952-65. PubMed ID: 21363998
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tissue distribution and elimination of [14C]apixaban in rats.
    Wang L; He K; Maxwell B; Grossman SJ; Tremaine LM; Humphreys WG; Zhang D
    Drug Metab Dispos; 2011 Feb; 39(2):256-64. PubMed ID: 21071521
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolism and excretion of a novel antianxiety drug candidate, CP-93,393, in Long Evans rats. Differentiation of regioisomeric glucuronides by LC/MS/MS.
    Prakash C; Soliman V
    Drug Metab Dispos; 1997 Nov; 25(11):1288-97. PubMed ID: 9351906
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Absorption, distribution, metabolism, and excretion of donepezil (Aricept) after a single oral administration to Rat.
    Matsui K; Mishima M; Nagai Y; Yuzuriha T; Yoshimura T
    Drug Metab Dispos; 1999 Dec; 27(12):1406-14. PubMed ID: 10570021
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolism, excretion, and pharmacokinetics of (3-{[4-tert-butyl-benzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid, an EP2 receptor-selective prostaglandin E2 agonist, in male and female Sprague-Dawley rats.
    Johnson KA; Prakash C
    Drug Metab Dispos; 2005 Aug; 33(8):1191-201. PubMed ID: 15886349
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolism distribution and excretion of a matrix metalloproteinase-13 inhibitor, 4-[4-(4-fluorophenoxy)-benzenesulfonylamino]tetrahydropyran-4-carboxylic acid hydroxyamide (CP-544439), in rats and dogs: assessment of the metabolic profile of CP-544439 in plasma and urine of humans.
    Dalvie D; Cosker T; Boyden T; Zhou S; Schroeder C; Potchoiba MJ
    Drug Metab Dispos; 2008 Sep; 36(9):1869-83. PubMed ID: 18566038
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacokinetics, tissue distribution, metabolism, and excretion of celecoxib in rats.
    Paulson SK; Zhang JY; Breau AP; Hribar JD; Liu NW; Jessen SM; Lawal YM; Cogburn JN; Gresk CJ; Markos CS; Maziasz TJ; Schoenhard GL; Burton EG
    Drug Metab Dispos; 2000 May; 28(5):514-21. PubMed ID: 10772629
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolism, pharmacokinetics and excretion of the GABA(A) receptor partial agonist [(14)C]CP-409,092 in rats.
    Kamel A; Obach RS; Tseng E; Sawant A
    Xenobiotica; 2010 Jun; 40(6):400-14. PubMed ID: 20334492
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolism and disposition of [14C]BMS-690514 after oral administration to rats, rabbits, and dogs.
    Hong H; Su H; Sun H; Allentoff A; Ekhato IV; Chando T; Caceres-Cortes J; Roongta V; Iyer RA; Humphreys WG; Christopher LJ
    Drug Metab Dispos; 2010 Jul; 38(7):1189-201. PubMed ID: 20363952
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Kinetics and disposition of hexarelin, a peptidic growth hormone secretagogue, in rats.
    Roumi M; Marleau S; du Souich P; Maggi T; Deghenghi R; Ong H
    Drug Metab Dispos; 2000 Jan; 28(1):44-50. PubMed ID: 10611139
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Toxicokinetics of 14C-endosulfan in male Sprague-Dawley rats following oral administration of single or repeated doses.
    Chan MP; Morisawa S; Nakayama A; Kawamoto Y; Sugimoto M; Yoneda M
    Environ Toxicol; 2005 Oct; 20(5):533-41. PubMed ID: 16161119
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Pharmacokinetics of aminomethylpropanol in rats following oral and a novel dermal study design.
    Saghir SA; Clark AJ; McClymont EL; Staley JL
    Food Chem Toxicol; 2008 Feb; 46(2):678-87. PubMed ID: 17961896
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolism, disposition, excretion, and pharmacokinetics of levormeloxifene, a selective estrogen receptor modulator, in the rat.
    Mountfield RJ; Kiehr B; John BA
    Drug Metab Dispos; 2000 May; 28(5):503-13. PubMed ID: 10772628
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Comparative metabolism of 14C-labeled apixaban in mice, rats, rabbits, dogs, and humans.
    Zhang D; He K; Raghavan N; Wang L; Mitroka J; Maxwell BD; Knabb RM; Frost C; Schuster A; Hao F; Gu Z; Humphreys WG; Grossman SJ
    Drug Metab Dispos; 2009 Aug; 37(8):1738-48. PubMed ID: 19420130
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Distribution and metabolism of the antipsychotic agent mazapertine succinate in rats.
    Caldwell GW; Wu WN; McKown LA; Diane Gauthier A; Masucci JA; Jones WJ; Leo GC; Reitz AB
    J Pharm Biomed Anal; 2006 May; 41(2):500-9. PubMed ID: 16386397
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Pharmacokinetics of prulifloxacin. 2nd communication: pharmacokinetics and effect on hepatic drug-metabolizing enzyme activities after repeated administration and transfer into fetus and milk after a single administration in rats.
    Okuyama Y; Momota K; Morino A
    Arzneimittelforschung; 1997 Mar; 47(3):285-92. PubMed ID: 9105547
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Studies on the metabolism and disposition of the new retinoid 4-[(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthyl)carbamoyl] benzoic acid. 1st communication: absorption, distribution, metabolism and excretion after topical application and subcutaneous administration in rats.
    Mizojiri K; Okabe H; Sugeno K; Esumi Y; Takaichi M; Miyake T; Seki H; Inaba A
    Arzneimittelforschung; 1997 Jan; 47(1):59-69. PubMed ID: 9037446
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Pharmacokinetics of NS-105, a novel cognition enhancer. 2nd communication: distribution and transfer into fetus and milk after single administration, and effects of repeated administration on pharmacokinetics and hepatic drug-metabolizing enzyme activities in rats.
    Mukai H; Sugimoto T; Ago M; Morino A; Takaichi M; Ogawa Y; Seki H; Matsuura C; Esumi Y
    Arzneimittelforschung; 1999 Dec; 49(12):977-85. PubMed ID: 10635441
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Absorption, distribution, metabolism, and elimination of the direct renin inhibitor aliskiren in healthy volunteers.
    Waldmeier F; Glaenzel U; Wirz B; Oberer L; Schmid D; Seiberling M; Valencia J; Riviere GJ; End P; Vaidyanathan S
    Drug Metab Dispos; 2007 Aug; 35(8):1418-28. PubMed ID: 17510248
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.