190 related articles for article (PubMed ID: 15486191)
1. The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice.
Pham NA; Jacobberger JW; Schimmer AD; Cao P; Gronda M; Hedley DW
Mol Cancer Ther; 2004 Oct; 3(10):1239-48. PubMed ID: 15486191
[TBL] [Abstract][Full Text] [Related]
2. Sulforaphane induces cell type-specific apoptosis in human breast cancer cell lines.
Pledgie-Tracy A; Sobolewski MD; Davidson NE
Mol Cancer Ther; 2007 Mar; 6(3):1013-21. PubMed ID: 17339367
[TBL] [Abstract][Full Text] [Related]
3. Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells.
Cho SD; Li G; Hu H; Jiang C; Kang KS; Lee YS; Kim SH; Lu J
Nutr Cancer; 2005; 52(2):213-24. PubMed ID: 16201852
[TBL] [Abstract][Full Text] [Related]
4. Apoptosis Induction in Primary Human Colorectal Cancer Cell Lines and Retarded Tumor Growth in SCID Mice by Sulforaphane.
Chen MJ; Tang WY; Hsu CW; Tsai YT; Wu JF; Lin CW; Cheng YM; Hsu YC
Evid Based Complement Alternat Med; 2012; 2012():415231. PubMed ID: 21804859
[TBL] [Abstract][Full Text] [Related]
5. Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.
Conaway CC; Wang CX; Pittman B; Yang YM; Schwartz JE; Tian D; McIntee EJ; Hecht SS; Chung FL
Cancer Res; 2005 Sep; 65(18):8548-57. PubMed ID: 16166336
[TBL] [Abstract][Full Text] [Related]
6. Growth inhibition, cell-cycle arrest and apoptosis in human T-cell leukemia by the isothiocyanate sulforaphane.
Fimognari C; Nüsse M; Cesari R; Iori R; Cantelli-Forti G; Hrelia P
Carcinogenesis; 2002 Apr; 23(4):581-6. PubMed ID: 11960909
[TBL] [Abstract][Full Text] [Related]
7. Effect of sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells.
Yeh CT; Yen GC
Carcinogenesis; 2005 Dec; 26(12):2138-48. PubMed ID: 16033772
[TBL] [Abstract][Full Text] [Related]
8. Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C.
Singh SV; Herman-Antosiewicz A; Singh AV; Lew KL; Srivastava SK; Kamath R; Brown KD; Zhang L; Baskaran R
J Biol Chem; 2004 Jun; 279(24):25813-22. PubMed ID: 15073169
[TBL] [Abstract][Full Text] [Related]
9. Sulforaphane generates reactive oxygen species leading to mitochondrial perturbation for apoptosis in human leukemia U937 cells.
Choi WY; Choi BT; Lee WH; Choi YH
Biomed Pharmacother; 2008 Nov; 62(9):637-44. PubMed ID: 18313257
[TBL] [Abstract][Full Text] [Related]
10. Targeting cell cycle machinery as a molecular mechanism of sulforaphane in prostate cancer prevention.
Wang L; Liu D; Ahmed T; Chung FL; Conaway C; Chiao JW
Int J Oncol; 2004 Jan; 24(1):187-92. PubMed ID: 14654956
[TBL] [Abstract][Full Text] [Related]
11. Sulforaphane: a naturally occurring mammary carcinoma mitotic inhibitor, which disrupts tubulin polymerization.
Jackson SJ; Singletary KW
Carcinogenesis; 2004 Feb; 25(2):219-27. PubMed ID: 14578157
[TBL] [Abstract][Full Text] [Related]
12. Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent.
Choi S; Singh SV
Cancer Res; 2005 Mar; 65(5):2035-43. PubMed ID: 15753404
[TBL] [Abstract][Full Text] [Related]
13. Sulforaphane suppresses TNF-alpha-mediated activation of NF-kappaB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3.
Moon DO; Kim MO; Kang SH; Choi YH; Kim GY
Cancer Lett; 2009 Feb; 274(1):132-42. PubMed ID: 18952368
[TBL] [Abstract][Full Text] [Related]
14. Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells.
Li Y; Zhang T; Korkaya H; Liu S; Lee HF; Newman B; Yu Y; Clouthier SG; Schwartz SJ; Wicha MS; Sun D
Clin Cancer Res; 2010 May; 16(9):2580-90. PubMed ID: 20388854
[TBL] [Abstract][Full Text] [Related]
15. Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells.
Gamet-Payrastre L; Li P; Lumeau S; Cassar G; Dupont MA; Chevolleau S; Gasc N; Tulliez J; Tercé F
Cancer Res; 2000 Mar; 60(5):1426-33. PubMed ID: 10728709
[TBL] [Abstract][Full Text] [Related]
16. Sulforaphane-mediated induction of a phase 2 detoxifying enzyme NAD(P)H:quinone reductase and apoptosis in human lymphoblastoid cells.
Misiewicz I; Skupińska K; Kowalska E; Lubiński J; Kasprzycka-Guttman T
Acta Biochim Pol; 2004; 51(3):711-21. PubMed ID: 15448733
[TBL] [Abstract][Full Text] [Related]
17. Sulforaphane increases the efficacy of doxorubicin in mouse fibroblasts characterized by p53 mutations.
Fimognari C; Nüsse M; Lenzi M; Sciuscio D; Cantelli-Forti G; Hrelia P
Mutat Res; 2006 Oct; 601(1-2):92-101. PubMed ID: 16843502
[TBL] [Abstract][Full Text] [Related]
18. Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line.
Herman-Antosiewicz A; Xiao H; Lew KL; Singh SV
Mol Cancer Ther; 2007 May; 6(5):1673-81. PubMed ID: 17513615
[TBL] [Abstract][Full Text] [Related]
19. Autophagy inhibition enhances sulforaphane-induced apoptosis in human breast cancer cells.
Kanematsu S; Uehara N; Miki H; Yoshizawa K; Kawanaka A; Yuri T; Tsubura A
Anticancer Res; 2010 Sep; 30(9):3381-90. PubMed ID: 20944112
[TBL] [Abstract][Full Text] [Related]
20. Cellular responses to cancer chemopreventive agent D,L-sulforaphane in human prostate cancer cells are initiated by mitochondrial reactive oxygen species.
Xiao D; Powolny AA; Antosiewicz J; Hahm ER; Bommareddy A; Zeng Y; Desai D; Amin S; Herman-Antosiewicz A; Singh SV
Pharm Res; 2009 Jul; 26(7):1729-38. PubMed ID: 19384467
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
