231 related articles for article (PubMed ID: 15501990)
1. Aberrant methylation of DPYD promoter, DPYD expression, and cellular sensitivity to 5-fluorouracil in cancer cells.
Noguchi T; Tanimoto K; Shimokuni T; Ukon K; Tsujimoto H; Fukushima M; Noguchi T; Kawahara K; Hiyama K; Nishiyama M
Clin Cancer Res; 2004 Oct; 10(20):7100-7. PubMed ID: 15501990
[TBL] [Abstract][Full Text] [Related]
2. Methylation of the DPYD promoter: an alternative mechanism for dihydropyrimidine dehydrogenase deficiency in cancer patients.
Ezzeldin HH; Lee AM; Mattison LK; Diasio RB
Clin Cancer Res; 2005 Dec; 11(24 Pt 1):8699-705. PubMed ID: 16361556
[TBL] [Abstract][Full Text] [Related]
3. Hypermethylation of the DPYD promoter region is not a major predictor of severe toxicity in 5-fluorouracil based chemotherapy.
Amstutz U; Farese S; Aebi S; Largiadèr CR
J Exp Clin Cancer Res; 2008 Oct; 27(1):54. PubMed ID: 18937829
[TBL] [Abstract][Full Text] [Related]
4. Sequence analysis of the 5'-flanking regions of human dihydropyrimidine dehydrogenase gene: identification of a new polymorphism related with effects of 5-fluorouracil.
Hasegawa T; Kim HS; Fukushima M; Wataya Y
Nucleosides Nucleotides Nucleic Acids; 2005; 24(4):233-42. PubMed ID: 16021908
[TBL] [Abstract][Full Text] [Related]
5. Activator protein accelerates dihydropyrimidine dehydrogenase gene transcription in cancer cells.
Ukon K; Tanimoto K; Shimokuni T; Noguchi T; Hiyama K; Tsujimoto H; Fukushima M; Toge T; Nishiyama M
Cancer Res; 2005 Feb; 65(3):1055-62. PubMed ID: 15705907
[TBL] [Abstract][Full Text] [Related]
6. [Dihydropyrimidine dehydrogenase activity and its genetic aberrations].
Ogura K
Gan To Kagaku Ryoho; 2006 Aug; 33(8):1041-8. PubMed ID: 16912518
[TBL] [Abstract][Full Text] [Related]
7. Two cases of 5-fluorouracil toxicity linked with gene variants in the DPYD gene.
Ofverholm A; Arkblad E; Skrtic S; Albertsson P; Shubbar E; Enerbäck C
Clin Biochem; 2010 Feb; 43(3):331-4. PubMed ID: 19822137
[TBL] [Abstract][Full Text] [Related]
8. Correlation between chemosensitivity and mRNA expression level of 5-fluorouracil-related metabolic enzymes during liver metastasis of colorectal cancer.
Okumura K; Shiomi H; Mekata E; Kaizuka M; Endo Y; Kurumi Y; Tani T
Oncol Rep; 2006 Apr; 15(4):875-82. PubMed ID: 16525674
[TBL] [Abstract][Full Text] [Related]
9. [Prediction of sensitivity to 5-fluorouracil (5-fu) by metabolic and target enzyme activities in colon cancer].
Yamada T; Tanaka N; Yokoi K; Ishikawa N; Seya T; Horiba K; Kanazawa Y; Shirakawa T; Ohkawa K; Kudoh H; Koizumi M; Yoshioka M; Shinji S; Yamashita K; Tajiri T
Gan To Kagaku Ryoho; 2006 Nov; 33(11):1603-9. PubMed ID: 17108726
[TBL] [Abstract][Full Text] [Related]
10. Role of genetic and nongenetic factors for fluorouracil treatment-related severe toxicity: a prospective clinical trial by the German 5-FU Toxicity Study Group.
Schwab M; Zanger UM; Marx C; Schaeffeler E; Klein K; Dippon J; Kerb R; Blievernicht J; Fischer J; Hofmann U; Bokemeyer C; Eichelbaum M;
J Clin Oncol; 2008 May; 26(13):2131-8. PubMed ID: 18299612
[TBL] [Abstract][Full Text] [Related]
11. Suppression of DPYD expression in RKO cells via DNA methylation in the regulatory region of the DPYD promoter: a potentially important epigenetic mechanism regulating DPYD expression.
Zhang X; Soong R; Wang K; Li L; Davie JR; Guarcello V; Diasio RB
Biochem Cell Biol; 2007 Jun; 85(3):337-46. PubMed ID: 17612628
[TBL] [Abstract][Full Text] [Related]
12. MicroRNA-494 sensitizes colon cancer cells to fluorouracil through regulation of DPYD.
Chai J; Dong W; Xie C; Wang L; Han DL; Wang S; Guo HL; Zhang ZL
IUBMB Life; 2015 Mar; 67(3):191-201. PubMed ID: 25873402
[TBL] [Abstract][Full Text] [Related]
13. [Anti-tumor effects of various interferons-alpha +5-fluorouracil via downregulation of dihydropyrimidine dehydrogenase in hepatoma cells].
Fan XY; Uchida H; Iwaki K; Kai S; Shibata K; Ohta M; Kitano S
Gan To Kagaku Ryoho; 2007 Jun; 34(6):957-9. PubMed ID: 17565266
[TBL] [Abstract][Full Text] [Related]
14. Up-regulation in dihydropyrimidine dehydrogenase activity by raltitrexed causes antagonism in combination with 5-fluorouracil.
Nozoe Y; Ogata Y; Araki Y; Sasatomi T; Fukumori H; Shirouzu K
Anticancer Res; 2003; 23(6C):4663-9. PubMed ID: 14981911
[TBL] [Abstract][Full Text] [Related]
15. Cloning and initial characterization of the human DPYD gene promoter.
Collie-Duguid ES; Johnston SJ; Powrie RH; Milano G; Etienne MC; Rochat B; Watson GC; McLeod HL
Biochem Biophys Res Commun; 2000 Apr; 271(1):28-35. PubMed ID: 10777676
[TBL] [Abstract][Full Text] [Related]
16. Long noncoding RNA LINC00261 induces chemosensitization to 5-fluorouracil by mediating methylation-dependent repression of DPYD in human esophageal cancer.
Lin K; Jiang H; Zhuang SS; Qin YS; Qiu GD; She YQ; Zheng JT; Chen C; Fang L; Zhang SY
FASEB J; 2019 Feb; 33(2):1972-1988. PubMed ID: 30226808
[TBL] [Abstract][Full Text] [Related]
17. Dihydropyrimidine dehydrogenase activity in 150 healthy Japanese volunteers and identification of novel mutations.
Ogura K; Ohnuma T; Minamide Y; Mizuno A; Nishiyama T; Nagashima S; Kanamaru M; Hiratsuka A; Watabe T; Uematsu T
Clin Cancer Res; 2005 Jul; 11(14):5104-11. PubMed ID: 16033824
[TBL] [Abstract][Full Text] [Related]
18. Clinical implications of dihydropyrimidine dehydrogenase (DPD) activity in 5-FU-based chemotherapy: mutations in the DPD gene, and DPD inhibitory fluoropyrimidines.
Omura K
Int J Clin Oncol; 2003 Jun; 8(3):132-8. PubMed ID: 12851836
[TBL] [Abstract][Full Text] [Related]
19. Dihydropyrimidine dehydrogenase (DPD) expression is negatively regulated by certain microRNAs in human lung tissues.
Hirota T; Date Y; Nishibatake Y; Takane H; Fukuoka Y; Taniguchi Y; Burioka N; Shimizu E; Nakamura H; Otsubo K; Ieiri I
Lung Cancer; 2012 Jul; 77(1):16-23. PubMed ID: 22306127
[TBL] [Abstract][Full Text] [Related]
20. Dihydropyrimidine dehydrogenase expression predicts survival outcome and chemosensitivity to 5-fluorouracil in patients with oral squamous cell carcinoma.
Kobayashi H; Koike T; Nakatsuka A; Kurita H; Sagara J; Taniguchi S; Kurashina K
Oral Oncol; 2005 Jan; 41(1):38-47. PubMed ID: 15598584
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
