BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

265 related articles for article (PubMed ID: 15504830)

  • 1. Chemical diversity of polyene macrolides produced by Streptomyces noursei ATCC 11455 and recombinant strain ERD44 with genetically altered polyketide synthase NysC.
    Bruheim P; Borgos SE; Tsan P; Sletta H; Ellingsen TE; Lancelin JM; Zotchev SB
    Antimicrob Agents Chemother; 2004 Nov; 48(11):4120-9. PubMed ID: 15504830
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effect of glucose limitation and specific mutations in the module 5 enoyl reductase domains in the nystatin and amphotericin polyketide synthases on polyene macrolide biosynthesis.
    Borgos SE; Sletta H; Fjaervik E; Brautaset T; Ellingsen TE; Gulliksen OM; Zotchev SB
    Arch Microbiol; 2006 Apr; 185(3):165-71. PubMed ID: 16416127
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New nystatin-related antifungal polyene macrolides with altered polyol region generated via biosynthetic engineering of Streptomyces noursei.
    Brautaset T; Sletta H; Degnes KF; Sekurova ON; Bakke I; Volokhan O; Andreassen T; Ellingsen TE; Zotchev SB
    Appl Environ Microbiol; 2011 Sep; 77(18):6636-43. PubMed ID: 21764946
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Initiation of polyene macrolide biosynthesis: interplay between polyketide synthase domains and modules as revealed via domain swapping, mutagenesis, and heterologous complementation.
    Heia S; Borgos SE; Sletta H; Escudero L; Seco EM; Malpartida F; Ellingsen TE; Zotchev SB
    Appl Environ Microbiol; 2011 Oct; 77(19):6982-90. PubMed ID: 21821762
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hexaene derivatives of nystatin produced as a result of an induced rearrangement within the nysC polyketide synthase gene in S. noursei ATCC 11455.
    Brautaset T; Bruheim P; Sletta H; Hagen L; Ellingsen TE; Strøm AR; Valla S; Zotchev SB
    Chem Biol; 2002 Mar; 9(3):367-73. PubMed ID: 11927262
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.
    Brautaset T; Sekurova ON; Sletta H; Ellingsen TE; StrŁm AR; Valla S; Zotchev SB
    Chem Biol; 2000 Jun; 7(6):395-403. PubMed ID: 10873841
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhancement of nystatin production by redirecting precursor fluxes after disruption of the tetramycin gene from Streptomyces ahygroscopicus.
    Ren J; Cui Y; Zhang F; Cui H; Ni X; Chen F; Li L; Xia H
    Microbiol Res; 2014; 169(7-8):602-8. PubMed ID: 24231162
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Nystatin-like Pseudonocardia polyene B1, a novel disaccharide-containing antifungal heptaene antibiotic.
    Kim HJ; Han CY; Park JS; Oh SH; Kang SH; Choi SS; Kim JM; Kwak JH; Kim ES
    Sci Rep; 2018 Sep; 8(1):13584. PubMed ID: 30206268
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei.
    Fjaervik E; Zotchev SB
    Appl Microbiol Biotechnol; 2005 Jun; 67(4):436-43. PubMed ID: 15700127
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of the P450 monooxygenase NysL, responsible for C-10 hydroxylation during biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei.
    Volokhan O; Sletta H; Ellingsen TE; Zotchev SB
    Appl Environ Microbiol; 2006 Apr; 72(4):2514-9. PubMed ID: 16597951
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Probing the structure-function relationship of polyene macrolides: engineered biosynthesis of soluble nystatin analogues.
    Borgos SE; Tsan P; Sletta H; Ellingsen TE; Lancelin JM; Zotchev SB
    J Med Chem; 2006 Apr; 49(8):2431-9. PubMed ID: 16610786
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of a gene cluster for antibacterial polyketide-derived antibiotic biosynthesis in the nystatin producer Streptomyces noursei ATCC 11455.
    Zotchev S; Haugan K; Sekurova O; Sletta H; Ellingsen TE; Valla S
    Microbiology (Reading); 2000 Mar; 146 ( Pt 3)():611-619. PubMed ID: 10746764
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Improved antifungal polyene macrolides via engineering of the nystatin biosynthetic genes in Streptomyces noursei.
    Brautaset T; Sletta H; Nedal A; Borgos SE; Degnes KF; Bakke I; Volokhan O; Sekurova ON; Treshalin ID; Mirchink EP; Dikiy A; Ellingsen TE; Zotchev SB
    Chem Biol; 2008 Nov; 15(11):1198-206. PubMed ID: 19022180
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Biosynthesis and pathway engineering of antifungal polyene macrolides in actinomycetes.
    Kong D; Lee MJ; Lin S; Kim ES
    J Ind Microbiol Biotechnol; 2013 Jun; 40(6):529-43. PubMed ID: 23515854
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Comparative analysis of in vitro antifungal activity and in vivo acute toxicity of the nystatin analogue S44HP produced via genetic engineering].
    Treshchalin ID; Sletta H; Borgos SE; Pereverzeva EP; Voeĭkova TA; Ellingsen TE; Zotchev SB
    Antibiot Khimioter; 2005; 50(7):18-22. PubMed ID: 16768209
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterization of the biosynthetic gene cluster of the polyene macrolide antibiotic reedsmycins from a marine-derived Streptomyces strain.
    Yao T; Liu Z; Li T; Zhang H; Liu J; Li H; Che Q; Zhu T; Li D; Li W
    Microb Cell Fact; 2018 Jun; 17(1):98. PubMed ID: 29914489
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.
    Ward SL; Hu Z; Schirmer A; Reid R; Revill WP; Reeves CD; Petrakovsky OV; Dong SD; Katz L
    Antimicrob Agents Chemother; 2004 Dec; 48(12):4703-12. PubMed ID: 15561847
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Analysis of the mycosamine biosynthesis and attachment genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455.
    Nedal A; Sletta H; Brautaset T; Borgos SE; Sekurova ON; Ellingsen TE; Zotchev SB
    Appl Environ Microbiol; 2007 Nov; 73(22):7400-7. PubMed ID: 17905880
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification and Predictions Regarding the Biosynthesis Pathway of Polyene Macrolides Produced by Streptomyces roseoflavus Men-myco-93-63.
    Han X; Wang J; Liu L; Shen F; Meng Q; Li X; Li Y; Liu D
    Appl Environ Microbiol; 2021 Apr; 87(10):. PubMed ID: 33637575
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin.
    Sletta H; Borgos SE; Bruheim P; Sekurova ON; Grasdalen H; Aune R; Ellingsen TE; Zotchev SB
    Antimicrob Agents Chemother; 2005 Nov; 49(11):4576-83. PubMed ID: 16251298
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.