BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 15507687)

  • 1. In silico evidence for DNA polymerase-beta's substrate-induced conformational change.
    Arora K; Schlick T
    Biophys J; 2004 Nov; 87(5):3088-99. PubMed ID: 15507687
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differing conformational pathways before and after chemistry for insertion of dATP versus dCTP opposite 8-oxoG in DNA polymerase beta.
    Wang Y; Reddy S; Beard WA; Wilson SH; Schlick T
    Biophys J; 2007 May; 92(9):3063-70. PubMed ID: 17293403
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mismatch-induced conformational distortions in polymerase beta support an induced-fit mechanism for fidelity.
    Arora K; Beard WA; Wilson SH; Schlick T
    Biochemistry; 2005 Oct; 44(40):13328-41. PubMed ID: 16201758
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Regulation of DNA repair fidelity by molecular checkpoints: "gates" in DNA polymerase beta's substrate selection.
    Radhakrishnan R; Arora K; Wang Y; Beard WA; Wilson SH; Schlick T
    Biochemistry; 2006 Dec; 45(51):15142-56. PubMed ID: 17176036
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Sequential side-chain residue motions transform the binary into the ternary state of DNA polymerase lambda.
    Foley MC; Arora K; Schlick T
    Biophys J; 2006 Nov; 91(9):3182-95. PubMed ID: 16920835
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Critical role of magnesium ions in DNA polymerase beta's closing and active site assembly.
    Yang L; Arora K; Beard WA; Wilson SH; Schlick T
    J Am Chem Soc; 2004 Jul; 126(27):8441-53. PubMed ID: 15238001
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In silico studies of the African swine fever virus DNA polymerase X support an induced-fit mechanism.
    Sampoli Benítez BA; Arora K; Schlick T
    Biophys J; 2006 Jan; 90(1):42-56. PubMed ID: 16214865
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Polymerase beta simulations suggest that Arg258 rotation is a slow step rather than large subdomain motions per se.
    Yang L; Beard WA; Wilson SH; Broyde S; Schlick T
    J Mol Biol; 2002 Apr; 317(5):651-71. PubMed ID: 11955015
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Local deformations revealed by dynamics simulations of DNA polymerase Beta with DNA mismatches at the primer terminus.
    Yang L; Beard W; Wilson S; Roux B; Broyde S; Schlick T
    J Mol Biol; 2002 Aug; 321(3):459-78. PubMed ID: 12162959
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Conformational transition pathway of polymerase beta/DNA upon binding correct incoming substrate.
    Arora K; Schlick T
    J Phys Chem B; 2005 Mar; 109(11):5358-67. PubMed ID: 16863202
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Substrate-dependent millisecond domain motions in DNA polymerase β.
    Berlow RB; Swain M; Dalal S; Sweasy JB; Loria JP
    J Mol Biol; 2012 Jun; 419(3-4):171-82. PubMed ID: 22446382
    [TBL] [Abstract][Full Text] [Related]  

  • 12. An AP endonuclease 1-DNA polymerase beta complex: theoretical prediction of interacting surfaces.
    Abyzov A; Uzun A; Strauss PR; Ilyin VA
    PLoS Comput Biol; 2008 Apr; 4(4):e1000066. PubMed ID: 18437203
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The nature of the DNA substrate influences pre-catalytic conformational changes of DNA polymerase β.
    Huang J; Alnajjar KS; Mahmoud MM; Eckenroth B; Doublié S; Sweasy JB
    J Biol Chem; 2018 Sep; 293(39):15084-15094. PubMed ID: 30068550
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fidelity discrimination in DNA polymerase beta: differing closing profiles for a mismatched (G:A) versus matched (G:C) base pair.
    Radhakrishnan R; Schlick T
    J Am Chem Soc; 2005 Sep; 127(38):13245-52. PubMed ID: 16173754
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Orchestration of cooperative events in DNA synthesis and repair mechanism unraveled by transition path sampling of DNA polymerase beta's closing.
    Radhakrishnan R; Schlick T
    Proc Natl Acad Sci U S A; 2004 Apr; 101(16):5970-5. PubMed ID: 15069184
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Correct and incorrect nucleotide incorporation pathways in DNA polymerase beta.
    Radhakrishnan R; Schlick T
    Biochem Biophys Res Commun; 2006 Nov; 350(3):521-9. PubMed ID: 17022941
    [TBL] [Abstract][Full Text] [Related]  

  • 17. I260Q DNA polymerase β highlights precatalytic conformational rearrangements critical for fidelity.
    Liptak C; Mahmoud MM; Eckenroth BE; Moreno MV; East K; Alnajjar KS; Huang J; Towle-Weicksel JB; Doublié S; Loria JP; Sweasy JB
    Nucleic Acids Res; 2018 Nov; 46(20):10740-10756. PubMed ID: 30239932
    [TBL] [Abstract][Full Text] [Related]  

  • 18. DNA structure and aspartate 276 influence nucleotide binding to human DNA polymerase beta. Implication for the identity of the rate-limiting conformational change.
    Vande Berg BJ; Beard WA; Wilson SH
    J Biol Chem; 2001 Feb; 276(5):3408-16. PubMed ID: 11024043
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA polymerase beta: effects of gapped DNA substrates on dNTP specificity, fidelity, processivity and conformational changes.
    Ahn J; Kraynov VS; Zhong X; Werneburg BG; Tsai MD
    Biochem J; 1998 Apr; 331 ( Pt 1)(Pt 1):79-87. PubMed ID: 9512464
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structures of human DNA polymerase beta complexed with DNA: implications for catalytic mechanism, processivity, and fidelity.
    Pelletier H; Sawaya MR; Wolfle W; Wilson SH; Kraut J
    Biochemistry; 1996 Oct; 35(39):12742-61. PubMed ID: 8841118
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.