123 related articles for article (PubMed ID: 15509504)
1. Enhanced in vivo selection of bone marrow cells by retroviral-mediated coexpression of mutant O6-methylguanine-DNA-methyltransferase and HOXB4.
Milsom MD; Woolford LB; Margison GP; Humphries RK; Fairbairn LJ
Mol Ther; 2004 Nov; 10(5):862-73. PubMed ID: 15509504
[TBL] [Abstract][Full Text] [Related]
2. Direct reversal of DNA damage by mutant methyltransferase protein protects mice against dose-intensified chemotherapy and leads to in vivo selection of hematopoietic stem cells.
Ragg S; Xu-Welliver M; Bailey J; D'Souza M; Cooper R; Chandra S; Seshadri R; Pegg AE; Williams DA
Cancer Res; 2000 Sep; 60(18):5187-95. PubMed ID: 11016647
[TBL] [Abstract][Full Text] [Related]
3. Drug selection of mutant methylguanine methyltransferase from different oncoretroviral backbones results in multilineage hematopoietic transgene expression in primary and secondary recipients.
Davis BM; Reese JS; Lingas K; Gerson SL
J Hematother Stem Cell Res; 2003 Aug; 12(4):375-87. PubMed ID: 12965075
[TBL] [Abstract][Full Text] [Related]
4. Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea.
Davis BM; Reese JS; Koç ON; Lee K; Schupp JE; Gerson SL
Cancer Res; 1997 Nov; 57(22):5093-9. PubMed ID: 9371508
[TBL] [Abstract][Full Text] [Related]
5. G156A MGMT-transduced human mesenchymal stem cells can be selectively enriched by O6-benzylguanine and BCNU.
Lee K; Gerson SL; Maitra B; Koç ON
J Hematother Stem Cell Res; 2001 Oct; 10(5):691-701. PubMed ID: 11672516
[TBL] [Abstract][Full Text] [Related]
6. Protection and in vivo selection of hematopoietic stem cells using temozolomide, O6-benzylguanine, and an alkyltransferase-expressing retroviral vector.
Sawai N; Zhou S; Vanin EF; Houghton P; Brent TP; Sorrentino BP
Mol Ther; 2001 Jan; 3(1):78-87. PubMed ID: 11162314
[TBL] [Abstract][Full Text] [Related]
7. Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones.
Jansen M; Bardenheuer W; Sorg UR; Seeber S; Flasshove M; Moritz T
Eur J Haematol; 2001 Jul; 67(1):2-13. PubMed ID: 11553261
[TBL] [Abstract][Full Text] [Related]
8. In vivo selection of hematopoietic progenitor cells and temozolomide dose intensification in rhesus macaques through lentiviral transduction with a drug resistance gene.
Larochelle A; Choi U; Shou Y; Naumann N; Loktionova NA; Clevenger JR; Krouse A; Metzger M; Donahue RE; Kang E; Stewart C; Persons D; Malech HL; Dunbar CE; Sorrentino BP
J Clin Invest; 2009 Jul; 119(7):1952-63. PubMed ID: 19509470
[TBL] [Abstract][Full Text] [Related]
9. Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow.
Kramer BA; Lemckert FA; Alexander IE; Gunning PW; McCowage GB
J Gene Med; 2006 Sep; 8(9):1071-85. PubMed ID: 16927363
[TBL] [Abstract][Full Text] [Related]
10. Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.
Maze R; Kurpad C; Pegg AE; Erickson LC; Williams DA
J Pharmacol Exp Ther; 1999 Sep; 290(3):1467-74. PubMed ID: 10454526
[TBL] [Abstract][Full Text] [Related]
11. Vector design for expression of O6-methylguanine-DNA methyltransferase in hematopoietic cells.
Schambach A; Baum C
DNA Repair (Amst); 2007 Aug; 6(8):1187-96. PubMed ID: 17482894
[TBL] [Abstract][Full Text] [Related]
12. Enhanced in vivo regenerative potential of HOXB4-transduced hematopoietic stem cells with regulation of their pool size.
Thorsteinsdottir U; Sauvageau G; Humphries RK
Blood; 1999 Oct; 94(8):2605-12. PubMed ID: 10515864
[TBL] [Abstract][Full Text] [Related]
13. In vivo selection of MGMT(P140K) lentivirus-transduced human NOD/SCID repopulating cells without pretransplant irradiation conditioning.
Zielske SP; Reese JS; Lingas KT; Donze JR; Gerson SL
J Clin Invest; 2003 Nov; 112(10):1561-70. PubMed ID: 14617757
[TBL] [Abstract][Full Text] [Related]
14. Efficient protection of cells from the genotoxicity of nitrosoureas by the retrovirus-mediated transfer of human O6-methylguanine-DNA methyltransferase using bicistronic vectors with human multidrug resistance gene 1.
Suzuki M; Sugimoto Y; Tsuruo T
Mutat Res; 1998 Jun; 401(1-2):133-41. PubMed ID: 9639692
[TBL] [Abstract][Full Text] [Related]
15. Retroviral coexpression of two different types of drug resistance genes to protect normal cells from combination chemotherapy.
Suzuki M; Sugimoto Y; Tsukahara S; Okochi E; Gottesman MM; Tsuruo T
Clin Cancer Res; 1997 Jun; 3(6):947-54. PubMed ID: 9815770
[TBL] [Abstract][Full Text] [Related]
16. Successful treatment of murine beta-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells.
Persons DA; Allay ER; Sawai N; Hargrove PW; Brent TP; Hanawa H; Nienhuis AW; Sorrentino BP
Blood; 2003 Jul; 102(2):506-13. PubMed ID: 12663444
[TBL] [Abstract][Full Text] [Related]
17. Lentivirus-mediated expression of mutant MGMTP140K protects human CD34+ cells against the combined toxicity of O6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide.
Chinnasamy D; Fairbairn LJ; Neuenfeldt J; Treisman JS; Hanson JP; Margison GP; Chinnasamy N
Hum Gene Ther; 2004 Aug; 15(8):758-69. PubMed ID: 15319033
[TBL] [Abstract][Full Text] [Related]
18. In vivo selection of hematopoietic stem cells transduced at a low multiplicity-of-infection with a foamy viral MGMT(P140K) vector.
Cai S; Ernstberger A; Wang H; Bailey BJ; Hartwell JR; Sinn AL; Eckermann O; Linka Y; Goebel WS; Hanenberg H; Pollok KE
Exp Hematol; 2008 Mar; 36(3):283-92. PubMed ID: 18279716
[TBL] [Abstract][Full Text] [Related]
19. A pilot study of dose-intensified procarbazine, CCNU, vincristine for poor prognosis brain tumors utilizing fibronectin-assisted, retroviral-mediated modification of CD34+ peripheral blood cells with O6-methylguanine DNA methyltransferase.
Cornetta K; Croop J; Dropcho E; Abonour R; Kieran MW; Kreissman S; Reeves L; Erickson LC; Williams DA
Cancer Gene Ther; 2006 Sep; 13(9):886-95. PubMed ID: 16645619
[TBL] [Abstract][Full Text] [Related]
20. Cloning and expression of canine O6-methylguanine-DNA methyltransferase in target cells, using gammaretroviral and lentiviral vectors.
Zaboikin M; Srinivasakumar N; Zaboikina T; Schuening F
Hum Gene Ther; 2004 Apr; 15(4):383-92. PubMed ID: 15053863
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]